(Q33998634)

24880126

30 July 2017

title

Heat shock protein 90β stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells (English)

1 reference

30 July 2017

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

author name string

Xiangyang Xiong

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Chengmei Liu

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Quqin Lu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Tao Liu

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Guoan Chen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Hai Rao

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Shiwen Luo

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

language of work or name

English

0 references

publication date

28 May 2014

1 reference

24880126

Experimental Cell Research

30 July 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

volume

326

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

page(s)

78-89

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4120946/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase

5 July 2018

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Cell surface heat shock protein 90 modulates prostate cancer cell adhesion and invasion through the integrin-β1/focal adhesion kinase/c-Src signaling pathway

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

5 July 2018

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Therapeutic efficacy of a novel focal adhesion kinase inhibitor TAE226 in ovarian carcinoma

5 July 2018

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Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress

5 July 2018

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Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

5 July 2018

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5 July 2018

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Cellular characterization of a novel focal adhesion kinase inhibitor

5 July 2018

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Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

5 July 2018

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Inhibitors of the HSP90 molecular chaperone: current status

5 July 2018

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Hsp90: a novel target for cancer therapy

5 July 2018

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Simultaneous activation of multiple signal transduction pathways confers poor prognosis in acute myelogenous leukemia

5 July 2018

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Lipid rafts serve as a signaling platform for nicotinic acetylcholine receptor clustering.

5 July 2018

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Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin

5 July 2018

1 reference

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HSP90 and the chaperoning of cancer

5 July 2018

1 reference

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The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

5 July 2018

1 reference

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Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers

5 July 2018

1 reference

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Cdc42 and Ras cooperate to mediate cellular transformation by intersectin-L.

5 July 2018

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The RAF proteins take centre stage

5 July 2018

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A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

5 July 2018

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Integrin alphavbeta3, requirement for VEGFR2-mediated activation of SAPK2/p38 and for Hsp90-dependent phosphorylation of focal adhesion kinase in endothelial cells activated by VEGF

5 July 2018

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Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

5 July 2018

1 reference

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Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1

5 July 2018

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Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co-chaperone p23.

5 July 2018

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Vascular endothelial growth factor (VEGF)-driven actin-based motility is mediated by VEGFR2 and requires concerted activation of stress-activated protein kinase 2 (SAPK2/p38) and geldanamycin-sensitive phosphorylation of focal adhesion kinase

5 July 2018

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5 July 2018

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The benzoquinone ansamycin geldanamycin stimulates proteolytic degradation of focal adhesion kinase

5 July 2018

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5 July 2018

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5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120946

Heat-shock protein hsp90 governs the activity of pp60v-src kinase

5 July 2018

1 reference

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A new technique for the assay of infectivity of human adenovirus 5 DNA

5 July 2018

1 reference

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5 July 2018

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5 July 2018

1 reference

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Safety, pharmacokinetic, and pharmacodynamic phase I dose-escalation trial of PF-00562271, an inhibitor of focal adhesion kinase, in advanced solid tumors

5 July 2018

1 reference

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Significance of heat-shock protein (HSP) 90 expression in acute myeloid leukemia cells

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120946

Inhibition of heat shock protein 90 function by 17-allylamino-17-demethoxy-geldanamycin in Hodgkin's lymphoma cells down-regulates Akt kinase, dephosphorylates extracellular signal-regulated kinase, and induces cell cycle arrest and cell death

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120946

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

29 October 2018

1 reference

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Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors.

29 October 2018

1 reference

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Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis

29 October 2018

1 reference

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Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120946

Structural basis for recruitment of the ATPase activator Aha1 to the Hsp90 chaperone machinery.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4120946

Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas

29 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.05.018

Focal adhesion kinase and its potential involvement in tumor invasion and metastasis

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.05.018

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

7 January 2021

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2014.05.018

Inhibition of mouse bladder tumor proliferation by murine interferon-gamma and its synergism with interferon-beta

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24880126

12 December 2020

inferred from PubMed ID database lookup

Overexpression of the focal adhesion kinase (p125FAK) in invasive human tumors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24880126

12 December 2020

inferred from PubMed ID database lookup

Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24880126

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.YEXCR.2014.05.018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24880126%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

24880126

1 reference