(Q34003319)

30 July 2017

Glycerol kinase deficiency alters expression of genes involved in lipid metabolism, carbohydrate metabolism, and insulin signaling (English)

1 reference

glycerol kinase deficiency

30 July 2017

1 reference

1 reference

3

Steve Horvath

1 reference

30 July 2017

Lola Rahib

1

1 reference

30 July 2017

Nicole K MacLennan

series ordinal

2

1 reference

30 July 2017

James C Liao

series ordinal

4

1 reference

30 July 2017

Katrina M Dipple

series ordinal

5

1 reference

30 July 2017

4 April 2007

1 reference

European Journal of Human Genetics

30 July 2017

1 reference

30 July 2017

15

1 reference

30 July 2017

6

1 reference

30 July 2017

646-657

1 reference

https://scigraph.springernature.com/pub.10.1038/sj.ejhg.5201801

30 July 2017

0 references

cites work

Phenotypes of patients with "simple" Mendelian disorders are complex traits: thresholds, modifiers, and systems dynamics

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Glycerol kinase deficiency: evidence for complexity in a single gene disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Single-gene disorders: what role could moonlighting enzymes play?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Consequences of complexity within biological networks: robustness and health, or vulnerability and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Glycerol as a correlate of impaired glucose tolerance: dissection of a complex system by use of a simple genetic trait

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Characterization of the human glycerol kinase promoter: identification of a functional HNF-4alpha binding site and evidence for transcriptional activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Mutations in the hepatocyte nuclear factor-4alpha gene in maturity-onset diabetes of the young (MODY1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Regulation of hepatic fasting response by PPARgamma coactivator-1alpha (PGC-1): requirement for hepatocyte nuclear factor 4alpha in gluconeogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Polymorphisms in both promoters of hepatocyte nuclear factor 4-alpha are associated with type 2 diabetes in the Amish

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The role of HNF4A variants in the risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Genetic variation near the hepatocyte nuclear factor-4 alpha gene predicts susceptibility to type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Sulfated glycans stimulate endocytosis of the cellular isoform of the prion protein, PrPC, in cultured cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

A futile metabolic cycle activated in adipocytes by antidiabetic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Type 2 diabetes mellitus: not quite exciting enough?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The brown adipose cell: a unique model for understanding the molecular mechanism of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The brown adipose cell: a model for understanding the molecular mechanisms of insulin resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The brown adipocyte: update on its metabolic role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Control of glyceroneogenic activity in rat brown adipose tissue.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Network component analysis: reconstruction of regulatory signals in biological systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli by using network component analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

X-linked glycerol kinase deficiency in the mouse leads to growth retardation, altered fat metabolism, autonomous glucocorticoid secretion and neonatal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Targeted disruption of glycerol kinase gene in mice: expression analysis in liver shows alterations in network partners related to glycerol kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Identifying biological themes within lists of genes with EASE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Gene therapy for murine glycerol kinase deficiency: importance of murine ortholog

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Oncogene jun encodes a sequence-specific trans-activator similar to AP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Signal transduction by the c-Jun N-terminal kinase (JNK)--from inflammation to development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Conserved family of glycerol kinase loci in Drosophila melanogaster

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Microcompartmentation of energy metabolism at the outer mitochondrial membrane: role in diabetes mellitus and other diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The voltage-dependent anion channel is the target for a new class of inhibitors of the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The mechanism of protein kinase C activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Regulation of phospholipase D2 activity by protein kinase C alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

The anti-apoptotic and growth stimulatory actions of leptin in human colon cancer cells involves activation of JNK mitogen activated protein kinase, JAK2 and PI3 kinase/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Role of Sp1 in insulin regulation of gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Transgenic angiopoietin-like (angptl)4 overexpression and targeted disruption of angptl4 and angptl3: regulation of triglyceride metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Adaptation to fasting by glycerol transport through aquaporin 7 in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Aquaporin 7 deficiency is associated with development of obesity through activation of adipose glycerol kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

Activation of the insulin gene promoter through a direct effect of hepatocyte nuclear factor 4 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Genetic analysis of HNF4A polymorphisms in Caucasian-American type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Subcellular distribution and kinetic properties of soluble and particulate-associated bovine adrenal 21vcerol kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

In vivo insulin regulation of skeletal muscle glycogen synthase in calorie-restricted and in ad libitum-fed rhesus monkeys.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

The role of glucose 6-phosphate in the control of glycogen synthase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Hyperinsulinaemia accelerates accumulation of cholesterol ester in aorta of rats with transplanted pancreas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Alterations in the expression and cellular localization of protein kinase C isozymes epsilon and theta are associated with insulin resistance in skeletal muscle of the high-fat-fed rat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.EJHG.5201801

7 January 2021

Identifiers

DOI

10.1038/SJ.EJHG.5201801

1 reference

30 July 2017

1 reference