(Q34007685)

30 July 2017

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title

Pathophysiology of the blood-brain barrier: animal models and methods (English)

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30 July 2017

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1

Brian T Hawkins

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30 July 2017

Richard D Egleton

2

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30 July 2017

publication date

1 January 2008

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Current Topics in Developmental Biology

30 July 2017

published in

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30 July 2017

volume

80

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30 July 2017

page(s)

277-309

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Inflammatory mediators and modulation of blood-brain barrier permeability

30 July 2017

cites work

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7 January 2021

Evidence for bulk flow of brain interstitial fluid: significance for physiology and pathology

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7 January 2021

Dynamics of CNS barriers: evolution, differentiation, and modulation

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7 January 2021

Tightness of the blood-brain barrier and evidence for brain interstitial fluid flow in the cuttlefish, Sepia officinalis.

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7 January 2021

Astrocyte-endothelial interactions at the blood-brain barrier

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7 January 2021

Regulation of blood-brain barrier Na,K,2Cl-cotransporter through phosphorylation during in vitro stroke conditions and nicotine exposure

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7 January 2021

Cytochrome P450 Cyp4x1 is a major P450 protein in mouse brain

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7 January 2021

Is the pial microvessel a good model for blood-brain barrier studies?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Isolating vessels from the mouse brain for gene expression analysis using laser capture microdissection.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Effect of diabetes mellitus on the permeability of the blood-brain barrier to insulin.

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

HIV-1 protein gp120 crosses the blood-brain barrier: role of adsorptive endocytosis

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Transport of human immunodeficiency virus type 1 pseudoviruses across the blood-brain barrier: role of envelope proteins and adsorptive endocytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Triglycerides induce leptin resistance at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The effects of high fat diets on the blood-brain barrier transport of leptin: failure or adaptation?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Magnetic resonance imaging-monitored acute blood-brain barrier changes in experimental traumatic brain injury

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Modulation of p-glycoprotein transport function at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

What is the blood-brain barrier (not)?

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https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor-related protein-mediated transcytosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

How to measure drug transport across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

A one-step procedure for isolation of poly(A)+ mRNA from isolated brain capillaries and endothelial cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Role of the pro-inflammatory cytokines TNF-alpha and IL-1beta in HIV-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Junctions between intimately apposed cell membranes in the vertebrate brain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Transcytosis of macromolecules through the blood-brain barrier: a cell biological perspective and critical appraisal

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Chronic inflammatory pain leads to increased blood-brain barrier permeability and tight junction protein alterations

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Biphasic cytoarchitecture and functional changes in the BBB induced by chronic inflammatory pain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Calcium modulation of adherens and tight junction function: a potential mechanism for blood-brain barrier disruption after stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Mannitol opening of the blood-brain barrier: regional variation in the permeability of sucrose, but not 86Rb+ or albumin.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier genomics and proteomics: elucidating phenotype, identifying disease targets and enabling brain drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Ultrastructure and blood-nerve barrier of chordotonal organs in the Drosophila embryo.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood barriers of the insect

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

6-Hydroxydopamine-induced alterations in blood-brain barrier permeability

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Drug metabolizing enzyme activities and superoxide formation in primary and immortalized rat brain endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Development of an in situ mouse brain perfusion model and its application to mdr1a P-glycoprotein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Multidrug resistance-associated proteins: expression and function in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier tight junction disruption in human immunodeficiency virus-1 encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Endocytosis of horseradish peroxidase by brain microvascular and umbilical vein endothelial cells in culture: an ultrastructural and morphometric study.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier permeability of novel [D-arg2]dermorphin (1-4) analogs: transport property is related to the slow onset of antinociceptive activity in the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Vascular matrix adhesion and the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Tissue- and cell type-specific expression of cytochrome P450 1A1 and cytochrome P450 1A2 mRNA in the mouse localized in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

New prospects for glycopeptide based analgesia: glycoside-induced penetration of the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Overexpression of multiple drug resistance genes in endothelial cells from patients with refractory epilepsy.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Studies on the internalization mechanism of cationic cell-penetrating peptides.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Development of neuropeptide drugs that cross the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Cerebral Vessels Have the Capacity to Transport Sodium and Potassium

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood–brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Molecular features, regulation, and function of monocarboxylate transporters: implications for drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The rat blood-brain barrier transcriptome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Patlak plots of Gd-DTPA MRI data yield blood-brain transfer constants concordant with those of 14C-sucrose in areas of blood-brain opening

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Experimental acute pancreatitis results in increased blood-brain barrier permeability in the rat: a potential role for tumor necrosis factor and interleukin 6.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Cyclooxygenase-2-positive macrophages infiltrate the Alzheimer's disease brain and damage the blood-brain barrier.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Gene and protein expression profiling of human cerebral endothelial cells activated with tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Expression polymorphism of the blood-brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

An intravital microscopy study of radiation-induced changes in permeability and leukocyte-endothelial cell interactions in the microvessels of the rat pia mater and cremaster muscle.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Where is the blood-brain barrier ... really?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Microglial reaction in the rat cerebral cortex induced by cortical spreading depression

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Isolation of metabolically active capillaries from rat brain1,2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

CYP1A1 and CYP1B1 in blood-brain interfaces: CYP1A1-dependent bioactivation of 7,12-dimethylbenz(a)anthracene in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Fluid-phase endocytosis by primary cultures of bovine brain microvessel endothelial cell monolayers

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Cortical spreading depression activates and upregulates MMP-9.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The function and integrity of the neurovascular unit rests upon the integration of the vascular and inflammatory cell systems

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Could chronic pain and spread of pain sensation be induced and maintained by glial activation?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Alcohol-induced oxidative stress in brain endothelial cells causes blood-brain barrier dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Protein markers of ischemic insult in brain endothelial cells identified using 2D gel electrophoresis and ICAT-based quantitative proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Regional brain uptake of noradrenaline following mechanical or osmotic opening of the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Regulation of tight junctions and loss of barrier function in pathophysiology

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Differential protein expression in brain capillary endothelial cells induced by hypoxia and posthypoxic reoxygenation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Effect of lambda-carrageenan-induced inflammatory pain on brain uptake of codeine and antinociception

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The blood-brain barrier/neurovascular unit in health and disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Increased blood-brain barrier permeability and altered tight junctions in experimental diabetes in the rat: contribution of hyperglycaemia and matrix metalloproteinases.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Decreased blood-brain barrier permeability to fluorescein in streptozotocin-treated rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Structure of the blood-brain barrier and its role in the transport of amino acids

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Comparative changes in the blood-brain barrier and cerebral infarction of SHR and WKY rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Prolonged and extensive IgG immunoreactivity after severe fluid-percussion injury in rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Astrocytic and neuronal biochemical markers in the sera of subjects with diabetes mellitus.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Molecular physiology and pathophysiology of tight junctions in the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Inflammatory pain alters blood-brain barrier permeability and tight junctional protein expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier tight junctions are altered during a 72-h exposure to lambda-carrageenan-induced inflammatory pain.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Alterations in blood-brain barrier ICAM-1 expression and brain microglial activation after lambda-carrageenan-induced inflammatory pain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Astrocytes induce blood–brain barrier properties in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Transferrin receptor on endothelium of brain capillaries

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Quantitative evaluation of BBB permeability after embolic stroke in rat using MRI.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Degeneration of noradrenergic fibres from the locus coeruleus causes tight-junction disorganisation in the rat brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Effects of first- and second-generation histamine-H1-receptor antagonists on the pentobarbital-induced loss of the righting reflex in streptozotocin-induced diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Organic anion-transporting polypeptide (OATP) transporter family and drug disposition

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Impaired glucose transport into the brain: the expanding spectrum of glucose transporter type 1 deficiency syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Quantitation and localization of blood-to-brain influx by magnetic resonance imaging and quantitative autoradiography in a model of transient focal ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Aquaporin subtypes in rat cerebral microvessels.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier dysfunction in parkinsonian midbrain in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Distribution and functional activity of P-glycoprotein and multidrug resistance-associated proteins in human brain microvascular endothelial cells in hippocampal sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Active efflux across the blood-brain barrier: role of the solute carrier family

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The critical component to establish in vitro BBB model: Pericyte

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Peroxidase Uptake by Glial Cells in Desheathed Ganglia of the Cockroach

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Studies on perineural junctional complexes and the sites of uptake of microperoxidase and lanthanum in the cockroach central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Early blood-brain barrier disruption in human focal brain ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

MDR1, the blood-brain barrier transporter, is associated with Parkinson's disease in ethnic Chinese

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Impaired function and expression of P-glycoprotein in blood-brain barrier of streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Mechanisms, challenges and opportunities in stroke

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

In vivo monitoring of fluorescent nanosphere delivery in anesthetized rats using an implantable fiber-optic microprobe.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Cation transport specificity at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Perinatal overfeeding in rats results in increased levels of plasma leptin but unchanged cerebrospinal leptin in adulthood.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Mammalian tight junctions in the regulation of epithelial differentiation and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Oligoclonal banding of IgG in CSF, blood-brain barrier function, and MRI findings in patients with sarcoidosis, systemic lupus erythematosus, and Behçet's disease involving the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Using real-time quantitative TaqMan RT-PCR to evaluate the role of dexamethasone in gene regulation of rat P-glycoproteins mdr1a/1b and cytochrome P450 3A1/2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Low-density lipoprotein receptor on endothelium of brain capillaries

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Development of rapid staining protocols for laser-capture microdissection of brain vessels from human and rat coupled to gene expression analyses.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Statins ameliorate endothelial barrier permeability changes in the cerebral tissue of streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

A putative nicotine pump at the metabolic blood-brain barrier of the tobacco hornworm

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Acute neurovascular unit protection by simvastatin in transient cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Possible involvement of gap junctions in the barrier function of tight junctions of brain and lung endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Carnitine: transport and physiological functions in the brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Disruption of the blood-brain barrier during TNBS colitis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Osmotic Blood-Brain Barrier Modification and Combination Chemotherapy: Concurrent Tumor Regression in Areas of Barrier Opening and Progression in Brain Regions Distant to Barrier Opening

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The blood-brain barrier and epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Cerebral microvascular endothelial cell Na-K-Cl cotransport: regulation by astrocyte-conditioned medium

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Modulation and compensation of the mRNA expression of energy related transporters in the brain of glucose transporter 1-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Measurement of brain uptake of radiolabeled substances using a tritiated water internal standard

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Fluorescein labelled dextrans as tracers for vascular permeability studies in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Evaluation of the effect of stress on the blood--brain barrier: critical role of the brain perfusion time

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Influence of surgical pain stress on the blood-brain barrier permeability in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Intravenous, non-viral RNAi gene therapy of brain cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The blood-brain barrier: bottleneck in brain drug development

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Tyrosine hydroxylase replacement in experimental Parkinson's disease with transvascular gene therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier genomics

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Human blood-brain barrier insulin receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Diabetes mellitus and dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Phenobarbital alters hepatic Mrp2 function by direct and indirect interactions.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Hyperglycemia and blood-brain barrier glucose transport

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Permeability of the blood-brain barrier to mannitol in the rat following 2450 MHz microwave irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Permeability of the developing blood-brain barrier to 14C-mannitol using the rat in situ brain perfusion technique

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Glucose transport to the brain: a systems model

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Fine structural localization of a blood-brain barrier to exogenous peroxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Verge: a novel vascular early response gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Mitosis and apoptosis of microglia in vivo induced by an anti-CR3 antibody which crosses the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Neurodegenerative disorders associated with diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Changes in cytoskeletal and tight junctional proteins correlate with decreased permeability induced by dexamethasone in cultured rat brain endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Identification, induction and localization of cytochrome P450s of the 3A-subfamily in mouse brain.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

In vivo evidence for ATP-dependent and P-glycoprotein-mediated transport of cyclosporin A at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Regulation of cytochrome P-450p by phenobarbital and phenobarbital-like inducers in adult rat hepatocytes in primary monolayer culture and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

GPCR signaling is required for blood-brain barrier formation in drosophila

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Brain-specific expression of an exogenous gene after i.v. administration

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier genomics, proteomics, and new transporter discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Vascular genomics of the human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Vascular proteomics and subtractive antibody expression cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Signaling at the gliovascular interface.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier glucose transporter: effects of hypo- and hyperglycemia revisited

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Species variation in pesticide-induced blood-brain barrier dysfunction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Endocytosis at the blood-brain barrier: from basic understanding to drug delivery strategies

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Kinetics and distribution volumes for tracers of different sizes in the brain plasma space

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Enhanced neuroprotective effects of basic fibroblast growth factor in regional brain ischemia after conjugation to a blood-brain barrier delivery vector

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Mechanisms of brain ion homeostasis during acute and chronic variations of plasma potassium

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Astroglial cell-induced expression of Na-K-Cl cotransporter in brain microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Analysis of MDR1 haplotypes in Parkinson's disease in a white population.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Effect of MDR1 haplotype on risk of Parkinson disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Minocycline reduces the lipopolysaccharide-induced inflammatory reaction, peroxynitrite-mediated nitration of proteins, disruption of the blood-brain barrier, and damage in the nigral dopaminergic system

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Capillary depletion method for quantification of blood-brain barrier transport of circulating peptides and plasma proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Small molecular drug transfer across the blood-brain barrier via carrier-mediated transport systems

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier leakage may lead to progression of temporal lobe epilepsy

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Brain inflammation in epilepsy: experimental and clinical evidence

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

VE-cadherin: adhesion at arm's length

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Synthetic amino acids and the nature of L-DOPA transport at the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Localization of norepinephrine and serotonin transporter in mouse brain capillary endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Nicotine downregulates alpha 2 isoform of Na,K-ATPase at the blood-brain barrier and brain in rats

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Assessment of stereoselectivity of trimethylphenylalanine analogues of delta-opioid [D-Pen(2),D-Pen(5)]-enkephalin.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Pain and the blood-brain barrier: obstacles to drug delivery

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Role of the MEOX2 homeobox gene in neurovascular dysfunction in Alzheimer disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Comparative analysis of cortical gene expression in mouse models of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Changes in cerebral perfusion precede plaque formation in multiple sclerosis: a longitudinal perfusion MRI study

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Role of constitutive androstane receptor in the in vivo induction of Mrp3 and CYP2B1/2 by phenobarbital.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

IgG-immunostaining in the intact rabbit brain: variable but significant staining of hippocampal and cerebellar neurons with anti-IgG.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Reciprocal interactions of insulin and insulin-like growth factor I in receptor-mediated transport across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Conjugation of brain-derived neurotrophic factor to a blood-brain barrier drug targeting system enables neuroprotection in regional brain ischemia following intravenous injection of the neurotrophin.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Intravenous nonviral gene therapy causes normalization of striatal tyrosine hydroxylase and reversal of motor impairment in experimental parkinsonism.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

TNF-alpha knockout and minocycline treatment attenuates blood-brain barrier leakage in MPTP-treated mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Differentially expressed genes in hypertensive rats developing cerebral ischemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Neurovascular mechanisms of Alzheimer's neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Measurement of solute transport across the blood-brain barrier in the perfused guinea pig brain: method and application to N-methyl-alpha-aminoisobutyric acid

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Determinants of benzodiazepine brain uptake: lipophilicity versus binding affinity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

Changing patterns in the neuropathogenesis of HIV during the HAART era.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2807%2980007-X

7 January 2021

10.1016/S0070-2153(07)80007-X

Identifiers

DOI

1 reference

30 July 2017

1 reference