(Q34013656)

30 July 2017

title

Evidence for hitchhiking of deleterious mutations within the human genome (English)

1 reference

30 July 2017

Sung Chun

1

0 references

Justin C Fay

object named as

Justin C Fay

series ordinal

2

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publication date

25 August 2011

1 reference

30 July 2017

1 reference

30 July 2017

volume

7

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30 July 2017

issue

8

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30 July 2017

page(s)

e1002240

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

25 August 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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5 July 2018

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Identification of deleterious mutations within three human genomes

5 July 2018

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

5 July 2018

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Constructing genomic maps of positive selection in humans: where do we go from here?

5 July 2018

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Signals of recent positive selection in a worldwide sample of human populations

5 July 2018

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Pervasive hitchhiking at coding and regulatory sites in humans

5 July 2018

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Assessing the evolutionary impact of amino acid mutations in the human genome

5 July 2018

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ASIP and TYR pigmentation variants associate with cutaneous melanoma and basal cell carcinoma

5 July 2018

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5 July 2018

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Proportionally more deleterious genetic variation in European than in African populations.

5 July 2018

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5 July 2018

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5 July 2018

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A new approach for using genome scans to detect recent positive selection in the human genome

5 July 2018

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5 July 2018

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Genomic signatures of positive selection in humans and the limits of outlier approaches

5 July 2018

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5 July 2018

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AN ESTIMATE OF THE MUTATIONAL DAMAGE IN MAN FROM DATA ON CONSANGUINEOUS MARRIAGES

5 July 2018

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A map of recent positive selection in the human genome

5 July 2018

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The accumulation of deleterious mutations in rice genomes: a hypothesis on the cost of domestication

5 July 2018

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SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans

5 July 2018

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Genomic regions exhibiting positive selection identified from dense genotype data

5 July 2018

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An evolutionary framework for common diseases: the ancestral-susceptibility model

5 July 2018

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Fitting background-selection predictions to levels of nucleotide variation and divergence along the human autosomes

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Initial sequence of the chimpanzee genome and comparison with the human genome

5 July 2018

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Soft sweeps: molecular population genetics of adaptation from standing genetic variation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The genetic association database

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Genetic signatures of strong recent positive selection at the lactase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Sequence Divergence, Functional Constraint, and Selection in Protein Evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Diabetes mellitus: a "thrifty" genotype rendered detrimental by "progress"?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Sequencing the chimpanzee genome: insights into human evolution and disease

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Dobzhansky-Muller incompatibilities in protein evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Sequence variation and haplotype structure at the human HFE locus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

A coalescent-based method for detecting and estimating recombination from gene sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Detecting a local signature of genetic hitchhiking along a recombining chromosome.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The neutral theory in the genomic era.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

On the allelic spectrum of human disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Positive and negative selection on the human genome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Prediction of deleterious human alleles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Hitchhiking under positive Darwinian selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Cysteine substitutions in epidermal growth factor-like domains of fibrillin-1: distinct effects on biochemical and clinical phenotypes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

When less is more: gene loss as an engine of evolutionary change

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The effect of deleterious mutations on neutral molecular variation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The origin of the major cystic fibrosis mutation (delta F508) in European populations.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Disruption of a GATA motif in the Duffy gene promoter abolishes erythroid gene expression in Duffy-negative individuals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Fifteen novel FBN1 mutations causing Marfan syndrome detected by heteroduplex analysis of genomic amplicons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

HLA disease associations: models for the study of complex human genetic disorders

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Cystic Fibrosis Heterozygote Resistance to Cholera Toxin in the Cystic Fibrosis Mouse Model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Linkage and the limits to natural selection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The evolutionary advantage of recombination

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The hitch-hiking effect of a favourable gene

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

5 July 2018

12 December 2020

Genetic hitchhiking and the evolution of reduced genetic activity of the Y sex chromosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Effects of linkage on rates of molecular evolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The legacy of domestication: accumulation of deleterious mutations in the dog genome

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002240

T-13910 DNA variant associated with lactase persistence interacts with Oct-1 and stimulates lactase promoter activity in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002240

Do ΔF508 heterozygotes have a selective advantage?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002240

THE DISTINCTIVE FOOTPRINTS OF LOCAL HITCHHIKING IN A VARIED ENVIRONMENT AND GLOBAL HITCHHIKING IN A SUBDIVIDED POPULATION

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1002240

Recombination and hitchhiking of deleterious alleles

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

The effect of deleterious alleles on adaptation in asexual populations.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3161959

Denaturing HPLC-identified novel FBN1 mutations, polymorphisms, and sequence variants in Marfan syndrome and related connective tissue disorders

29 October 2018

1 reference

12 December 2020

The origin and spread of the HFE-C282Y haemochromatosis mutation

1 reference

12 December 2020

Adaptive evolution of asexual populations under Muller's ratchet

1 reference

12 December 2020

Congenital bilateral absence of the vas deferens. A primarily genital form of cystic fibrosis

1 reference

12 December 2020

The Human Gene Mutation Database (HGMD) and its exploitation in the study of mutational mechanisms

1 reference

12 December 2020

Mutation-selection balance and the evolutionary advantage of sex and recombination

1 reference

12 December 2020

MUTATION LOAD AND THE SURVIVAL OF SMALL POPULATIONS.

1 reference

12 December 2020

MULLER'S RATCHET AND MUTATIONAL MELTDOWNS

1 reference

12 December 2020

Risk of Population Extinction from Fixation of New Deleterious Mutations

1 reference

12 December 2020

The effect of recombination on background selection

1 reference

12 December 2020

Natural selection and the evolutionary history of major histocompatibility complex loci

1 reference

12 December 2020

10.1371/JOURNAL.PGEN.1002240

Identifiers

DOI

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30 July 2017

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30 July 2017

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