(Q34017103)

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New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells

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Europe PubMed Central

PubMed publication ID

30 July 2017

New pyrazolo-[3,4-d]-pyrimidine derivative Src kinase inhibitors lead to cell cycle arrest and tumor growth reduction of human medulloblastoma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

medulloblastoma

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Francesca Pentimalli

object named as

Francesca Pentimalli

6

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Adriano Angelucci

object named as

Adriano Angelucci

3

0 references

object named as

Mauro Bologna

10

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Antonio Giordano

object named as

Antonio Giordano

12

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object named as

Biagio Pucci

8

0 references

11

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Maurizio Botta

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Silvia Schenone

2

object named as

Silvia Schenone

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

4

object named as

Martina Cozzi

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

7

object named as

Andrew Puca

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Valentina Caracciolo

5

object named as

Valentina Caracciolo

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Alessandra Rossi

1

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Europe PubMed Central

PubMed publication ID

30 July 2017

Raffaele La Montagna

9

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Europe PubMed Central

PubMed publication ID

30 July 2017

language of work or name

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publication date

30 March 2010

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Europe PubMed Central

PubMed publication ID

30 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

24

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Europe PubMed Central

PubMed publication ID

30 July 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

2881-2892

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Kinome profiling in pediatric brain tumors as a new approach for target discovery

1 reference

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28 July 2018

Combined radio- and chemotherapy of brain tumours in adult patients.

1 reference

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28 July 2018

Improving the prognosis for patients with glioblastoma: the rationale for targeting Src.

1 reference

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28 July 2018

The antiretroviral nucleoside analogue Abacavir reduces cell growth and promotes differentiation of human medulloblastoma cells

1 reference

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28 July 2018

Novel agents on the horizon for cancer therapy

1 reference

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28 July 2018

Medulloblastoma in children under the age of three years: a retrospective Canadian review

1 reference

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28 July 2018

Inhibition of matrix metalloproteinase-2 enhances radiosensitivity by abrogating radiation-induced FoxM1-mediated G2/M arrest in A549 lung cancer cells

1 reference

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28 July 2018

Analysis of apoptosis and expression of genes related to apoptosis in cultures of follicles derived from vitrified and non-vitrified ovaries

1 reference

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28 July 2018

Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy

1 reference

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28 July 2018

Evidence that resistance to nilotinib may be due to BCR-ABL, Pgp, or Src kinase overexpression

1 reference

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28 July 2018

Signaling pathways in medulloblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Flexibility and charge asymmetry in the activation loop of Src tyrosine kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Medulloblastoma: from molecular pathology to therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Antiproliferative and proapoptotic activities of new pyrazolo[3,4-d]pyrimidine derivative Src kinase inhibitors in human osteosarcoma cells

1 reference

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Apoptosis by dietary factors: the suicide solution for delaying cancer growth

1 reference

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28 July 2018

Pyrazolo[3,4-d]pyrimidines c-Src inhibitors reduce epidermal growth factor-induced migration in prostate cancer cells

1 reference

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28 July 2018

Role of ABC transporters in the chemoresistance of human gliomas.

1 reference

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28 July 2018

Pyrazolo[3,4-d]pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Garcinol modulates tyrosine phosphorylation of FAK and subsequently induces apoptosis through down-regulation of Src, ERK, and Akt survival signaling in human colon cancer cells

1 reference

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28 July 2018

Antiproliferative activity of new 1-aryl-4-amino-1H-pyrazolo[3,4-d]pyrimidine derivatives toward the human epidermoid carcinoma A431 cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

S-phase inhibition of cell cycle progression by a novel class of pyridopyrimidine tyrosine kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

New pyrazolo[3,4-d]pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Up-regulation of GADD34 mediates the synergistic anticancer activity of mitomycin C and a gamma134.5 deleted oncolytic herpes virus (G207).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Pyrazolo[3,4-d]pyrimidines endowed with antiproliferative activity on ductal infiltrating carcinoma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

28 July 2018

Src family kinases in tumor progression and metastasis

1 reference

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28 July 2018

Src in cancer: deregulation and consequences for cell behaviour

1 reference

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Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells

1 reference

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28 July 2018

When X-ray-inducible proteins meet DNA double strand break repair

1 reference

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28 July 2018

BCL-2 family members and the mitochondria in apoptosis

1 reference

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28 July 2018

Mitochondria and apoptosis

1 reference

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Caspases: enemies within

1 reference

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28 July 2018

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

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Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation

1 reference

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Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

1 reference

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cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

1 reference

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Immunolocalization of the cellular src protein in interphase and mitotic NIH c-src overexpresser cells

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

29 October 2018

SRC directly phosphorylates Bif-1 and prevents its interaction with Bax and the initiation of anoikis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2909284

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Different thresholds of MPF inactivation are responsible for controlling different mitotic events in mammalian cell division.

1 reference

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Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.

1 reference

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Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest

1 reference

https://pubmed.ncbi.nlm.nih.gov/20354138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyrazolo-pyrimidine-derived c-Src inhibitor reduces angiogenesis and survival of squamous carcinoma cells by suppressing vascular endothelial growth factor production and signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20354138

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1096/FJ.09-148593

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

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