(Q34037014)

25053236

30 July 2017

title

Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer (English)

1 reference

30 July 2017

1 reference

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

W Nathaniel Brennen

1

1 reference

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13 June 2020

D Marc Rosen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

George J Netto

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

John T Isaacs

5

1 reference

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13 June 2020

Samuel R Denmeade

6

1 reference

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13 June 2020

language of work or name

1 reference

22 July 2014

1 reference

30 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

74

1 reference

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13 June 2020

issue

13

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13 June 2020

page(s)

1308-1319

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

Targeting fibroblast activation protein in tumor stroma with chimeric antigen receptor T cells can inhibit tumor growth and augment host immunity without severe toxicity

13 June 2020

cites work

1 reference

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Fibroblast activation protein expression by stromal cells and tumor-associated macrophages in human breast cancer.

5 July 2018

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Mesenchymal stem cells as a vector for the inflammatory prostate microenvironment

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia

5 July 2018

1 reference

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Depletion of stromal cells expressing fibroblast activation protein-α from skeletal muscle and bone marrow results in cachexia and anemia.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

5 July 2018

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Quantification of Mesenchymal Stem Cells (MSCs) at sites of human prostate cancer

5 July 2018

1 reference

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Targeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug

5 July 2018

1 reference

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Engineering enzymatically activated "molecular grenades" for cancer

5 July 2018

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Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Rationale behind targeting fibroblast activation protein-expressing carcinoma-associated fibroblasts as a novel chemotherapeutic strategy

5 July 2018

1 reference

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Phase 1 and 2 studies demonstrate the safety and efficacy of intraprostatic injection of PRX302 for the targeted treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

A Trojan horse in drug development: targeting of thapsigargins towards prostate cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Carcinoma-associated fibroblast-like differentiation of human mesenchymal stem cells

5 July 2018

1 reference

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Seprase: an overview of an important matrix serine protease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

A prostate-specific antigen-activated channel-forming toxin as therapy for prostatic disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Effect of fibroblast activation protein and alpha2-antiplasmin cleaving enzyme on collagen types I, III, and IV.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Fibroblast activation protein is expressed by rheumatoid myofibroblast-like synoviocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Docetaxel-associated epiphora

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Fibroblast activation protein: a serine protease expressed at the remodeling interface in idiopathic pulmonary fibrosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Docetaxel administration schedule: from fever to tears? A review of randomised studies

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Docetaxel for treatment of solid tumours: a systematic review of clinical data

5 July 2018

1 reference

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The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Prolyl peptidases: a serine protease subfamily with high potential for drug discovery.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Targeted disruption of mouse fibroblast activation protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Docetaxel vs doxorubicin in metastatic breast cancer resistant to alkylating chemotherapy

5 July 2018

1 reference

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Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4130904

Prostate-specific antigen-activated thapsigargin prodrug as targeted therapy for prostate cancer

5 July 2018

1 reference

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Design, synthesis, and pharmacological evaluation of thapsigargin analogues for targeting apoptosis to prostatic cancer cells

21 January 2018

1 reference

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Applying linear interaction energy method for rational design of noncompetitive allosteric inhibitors of the sarco- and endoplasmic reticulum calcium-ATPase

21 January 2018

1 reference

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Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22847

Kinetics of thapsigargin-Ca(2+)-ATPase (sarcoplasmic reticulum) interaction reveals a two-step binding mechanism and picomolar inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.22847

Regulation and heteromeric structure of the fibroblast activation protein in normal and transformed cells of mesenchymal and neuroectodermal origin

21 January 2018

1 reference

12 December 2020

Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis

1 reference

12 December 2020

Thapsigargin analogues for targeting programmed death of androgen-independent prostate cancer cells

1 reference

12 December 2020

The carcinoma-associated fibroblast expressing fibroblast activation protein and escape from immune surveillance

1 reference

12 December 2020

Identifiers

DOI

10.1002/PROS.22847

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

release_qipvu5ux6naftnwavjeynqz4da

13 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qipvu5ux6naftnwavjeynqz4da

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25053236%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

25053236

1 reference