(Q34041550)

30 July 2017

title

Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance (English)

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30 July 2017

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3

Florent Allagnat

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30 July 2017

Alessandra K. Cardozo

object named as

Alessandra K Cardozo

6

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Esteban N. Gurzov

object named as

Esteban N Gurzov

5

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author name string

Maikel L Colli

1

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30 July 2017

Tatiane C Nogueira

2

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30 July 2017

Daniel A Cunha

4

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30 July 2017

Merja Roivainen

7

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30 July 2017

Anne Op de Beeck

8

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30 July 2017

Decio L Eizirik

9

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30 July 2017

publication date

22 September 2011

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30 July 2017

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30 July 2017

volume

7

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30 July 2017

issue

9

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30 July 2017

page(s)

e1002267

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

22 September 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.

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PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells

5 July 2018

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Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

5 July 2018

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The imbalance between Bim and Mcl-1 expression controls the survival of human myeloma cells

5 July 2018

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Mechanisms of coxsackievirus B5 mediated beta-cell death depend on the multiplicity of infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

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5 July 2018

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5 July 2018

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A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Glucose promotes survival of rat pancreatic beta cells by activating synthesis of proteins which suppress a constitutive apoptotic program

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Relative abundance of enterovirus serotypes in sewage differs from that in patients: clinical and epidemiological implications

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Increased Incidence of Insulin-Dependent Diabetes Mellitus Following an Epidemic of Coxsackievirus B5

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines

5 July 2018

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Isolation of a virus from the pancreas of a child with diabetic ketoacidosis

5 July 2018

1 reference

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Inverse relationship between cytotoxicity of free fatty acids in pancreatic islet cells and cellular triglyceride accumulation.

5 July 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002267

Central nervous system apoptosis in human herpes simplex virus and cytomegalovirus encephalitis

21 January 2018

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Disruption of Mcl-1.Bim complex in granzyme B-mediated mitochondrial apoptosis

21 January 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002267

Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis

21 January 2018

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Mechanisms of coxsackievirus-induced damage to human pancreatic beta-cells

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3178579

Increased level of interferon-alpha in blood of patients with insulin-dependent diabetes mellitus: relationship with coxsackievirus B infection

28 October 2018

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12 December 2020

Apoptosis in myocarditis and dilated cardiomyopathy: does enterovirus genome persistence protect from apoptosis? An endomyocardial biopsy study

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12 December 2020

Coxsackieviral-mediated diabetes: induction requires antigen-presenting cells and is accompanied by phagocytosis of beta cells

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12 December 2020

A new in vitro model for the study of pancreatic A and B cells

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12 December 2020

A prospective study of the role of coxsackie B and other enterovirus infections in the pathogenesis of IDDM. Childhood Diabetes in Finland (DiMe) Study Group

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12 December 2020

Interferon-alpha as a mediator of polyinosinic:polycytidylic acid-induced type 1 diabetes

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12 December 2020

Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002267

Identifiers

DOI

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30 July 2017

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30 July 2017

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