(Q84285839)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

Signaling by IL-1beta+IFN-gamma and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic beta-cell apoptosis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

Fernanda Ortis

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

author name string

D A Cunha

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

G Gosset

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

M Li

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

A K Cardozo

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

D L Eizirik

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

publication date

24 July 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

3 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

page(s)

1539-1550

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/cdd.2009.99

3 February 2020

exact match

0 references

cites work

The burden of mortality attributable to diabetes: realistic estimates for the year 2000

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Death-defying immunity: do apoptotic cells influence antigen processing and presentation?

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

An immune origin of type 2 diabetes?

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Exposure of human islets to cytokines can result in disproportionately elevated proinsulin release

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

The cytokine interleukin-1beta reduces the docking and fusion of insulin granules in pancreatic beta-cells, preferentially decreasing the first phase of exocytosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Cytokines suppress human islet function irrespective of their effects on nitric oxide generation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Transcriptional regulation of the endoplasmic reticulum stress gene chop in pancreatic insulin-producing cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

The role for endoplasmic reticulum stress in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Nitric oxide-induced apoptosis in pancreatic beta cells is mediated by the endoplasmic reticulum stress pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

The BCL-2 protein family: opposing activities that mediate cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Apoptosis-inducing factor: vital and lethal

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Molecular cloning of a novel polypeptide, DP5, induced during programmed neuronal death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

harakiri, a novel regulator of cell death, encodes a protein that activates apoptosis and interacts selectively with survival-promoting proteins Bcl-2 and Bcl-X(L)

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Discovery of Gene Networks Regulating Cytokine-Induced Dysfunction and Apoptosis in Insulin-Producing INS-1 Cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

dp5/HRK is a c-Jun target gene and required for apoptosis induced by potassium deprivation in cerebellar granule neurons

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Initiation and execution of lipotoxic ER stress in pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

AP-1 as a regulator of cell life and death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Role of NF-kappaB in beta-cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Transcriptional regulation via the NF-kappaB signaling module.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

A peptide inhibitor of c-Jun N-terminal kinase protects against excitotoxicity and cerebral ischemia

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Mitochondria and endoplasmic reticulum: the lethal interorganelle cross-talk

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

The endoplasmic reticulum in apoptosis and autophagy: role of the BCL-2 protein family.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Translational control of proinsulin synthesis by glucose

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Expression of neuronal traits in pancreatic beta cells. Implication of neuron-restrictive silencing factor/repressor element silencing transcription factor, a neuron-restrictive silencer.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Use of a systems biology approach to understand pancreatic beta-cell death in Type 1 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Regulation of transcription factors by nitric oxide in neurons and in neural-derived tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

ER stress triggers apoptosis by activating BH3-only protein Bim

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Bcl-2 family on guard at the ER.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.99

7 January 2021

Identifiers

DOI

10.1038/CDD.2009.99

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19629134%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference