(Q34046241)

30 July 2017

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title

Antimalarial drug development and new targets (English)

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30 July 2017

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Macreadie I

1

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30 July 2017

Ginsburg H

series ordinal

2

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30 July 2017

Sirawaraporn W

series ordinal

3

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30 July 2017

Tilley L

series ordinal

4

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30 July 2017

publication date

1 October 2000

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30 July 2017

published in

Trends in Parasitology

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30 July 2017

volume

16

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30 July 2017

issue

10

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30 July 2017

page(s)

438-444

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An overview of chemotherapeutic targets for antimalarial drug discovery

30 July 2017

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Yeast as a model system to study drugs effective against apicomplexan proteins

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Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites

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Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Inhibition by chloroquine of a novel haem polymerase enzyme activity in malaria trophozoites

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7 January 2021

Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action

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7 January 2021

Inhibition of the peroxidative degradation of haem as the basis of action of chloroquine and other quinoline antimalarials

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7 January 2021

The chemical basis for the ferriprotoporphyrin IX-chloroquine complex induced lipid peroxidation

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7 January 2021

Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite

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7 January 2021

Complex polymorphisms in an approximately 330 kDa protein are linked to chloroquine-resistant P. falciparum in Southeast Asia and Africa

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7 January 2021

Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum

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7 January 2021

Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross

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7 January 2021

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7 January 2021

Kinetic characterization of Na+/H+ antiport of Plasmodium falciparum membrane

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7 January 2021

Structure, function and regulation of the vacuolar (H+)-ATPase

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7 January 2021

Cloning and characterization of the vacuolar ATPase B subunit from Plasmodium falciparum

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7 January 2021

Cloning and characterization of a vacuolar ATPase A subunit homologue from Plasmodium falciparum

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7 January 2021

A nutrient-permeable channel on the intraerythrocytic malaria parasite

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7 January 2021

Passive Ca(2+) transport and Ca(2+)-dependent K(+) transport in Plasmodium falciparum-infected red cells

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7 January 2021

L-nucleoside analogues as potential antimalarials that selectively target Plasmodium falciparum adenosine deaminase

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7 January 2021

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7 January 2021

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7 January 2021

A plastid of probable green algal origin in Apicomplexan parasites.

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7 January 2021

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7 January 2021

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7 January 2021

Apicomplexan plastids as drug targets

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7 January 2021

Invasion of hereditary ovalocytes by Plasmodium falciparum in vitro and its relation to intracellular ATP concentration

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7 January 2021

Three-dimensional structure of M. tuberculosis dihydrofolate reductase reveals opportunities for the design of novel tuberculosis drugs

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7 January 2021

In the human malaria parasite Plasmodium falciparum, polyamines are synthesized by a bifunctional ornithine decarboxylase, S-adenosylmethionine decarboxylase

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7 January 2021

Polyamines as targets for therapeutic intervention

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7 January 2021

10.1016/S0169-4758(00)01758-0

Identifiers

DOI

1 reference

release_ovrpcpthizanxol74p2h566ujy

30 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ovrpcpthizanxol74p2h566ujy

24 November 2022

mapped directly with Wikidata item

1 reference