(Q34057091)

English

Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog

scientific article

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Trypanosoma brucei translation initiation factor homolog EIF4E6 forms a tripartite cytosolic complex with EIF4G5 and a capping enzyme homolog (English)

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Trypanosoma brucei

0 references

voltage-dependent anion-selective channel 2

1 reference

5 February 2019

Eukaryotic translation initiation factor 4E type 6

1 reference

5 February 2019

Eukaryotic translation initiation factor 4 gamma 5

1 reference

6 February 2019

paraflagellar rod component, putative

1 reference

6 February 2019

G5-interacting protein

1 reference

6 February 2019

Edward Darżynkiewicz

9

object named as

Edward Darzynkiewicz

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Janaina de Freitas Nascimento

1 reference

ORCID Public Data File 2021

5

object named as

Edwin A Saada

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

James A Wohlschlegel

12

object named as

James A Wohlschlegel

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

author name string

Eden R Freire

1

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Amaranta M Malvezzi

2

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Ajay A Vashisht

3

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Joanna Zuberek

4

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Gerasimos Langousis

6

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Janaína D F Nascimento

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Danielle Moura

8

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Kent Hill

10

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Osvaldo P de Melo Neto

11

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Nancy R Sturm

13

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

David A Campbell

14

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

publication date

16 May 2014

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

Eukaryotic Cell

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

13

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

896-908

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

A new strategy of RNA interference that targets heterologous sequences reveals CITFA1 as an essential component of class I transcription factor A in Trypanosoma brucei.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Comparative ribosome profiling reveals extensive translational complexity in different Trypanosoma brucei life cycle stages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Mouse infection and pathogenesis by Trypanosoma brucei motility mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

The spliced leader trans-splicing mechanism in different organisms: molecular details and possible biological roles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Strategies to construct null and conditional null Trypanosoma brucei mutants using Cre-recombinase and loxP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Identification of essential and non-essential protein kinases by a fusion PCR method for efficient production of transgenic Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Structural Analysis of the DAP5 MIF4G Domain and Its Interaction with eIF4A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Genome organization is a major component of gene expression control in response to stress and during the cell division cycle in trypanosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Architecture of the trypanosome RNA editing accessory complex, MRB1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Developmental regulation of gene expression in the absence of transcriptional control: the case of kinetoplastids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Enzymology of RNA cap synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

A novel 4E-interacting protein in Leishmania is involved in stage-specific translation pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Independent analysis of the flagellum surface and matrix proteomes provides insight into flagellum signaling in mammalian-infectious Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Molecular mechanisms underlying the control of antigenic variation in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Epigenetics and transcriptional control in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Social motility in african trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Coordinated gene expression by post-transcriptional regulons in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

TriTrypDB: a functional genomic resource for the Trypanosomatidae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Hypermethylated cap 4 maximizes Trypanosoma brucei translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Intrinsic RNA binding by the eukaryotic initiation factor 4F depends on a minimal RNA length but not on the m7G cap.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Evolutionary changes in the Leishmania eIF4F complex involve variations in the eIF4E-eIF4G interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Protein structure prediction on the Web: a case study using the Phyre server

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Identification of a cytoplasmic complex that adds a cap onto 5'-monophosphate RNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Requirement of RNA binding of mammalian eukaryotic translation initiation factor 4GI (eIF4GI) for efficient interaction of eIF4E with the mRNA cap.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Trypanosoma brucei spliced leader RNA maturation by the cap 1 2'-O-ribose methyltransferase and SLA1 H/ACA snoRNA pseudouridine synthase complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Insights into the genome sequence of a free-living Kinetoplastid: Bodo saltans (Kinetoplastida: Euglenozoa)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Heat shock causes a decrease in polysomes and the appearance of stress granules in trypanosomes independently of eIF2(alpha) phosphorylation at Thr169

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Depletion of the cap-associated isoform of translation factor eIF4G induces germline apoptosis in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Developmental regulation of gene expression in trypanosomatid parasitic protozoa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Binding specificities and potential roles of isoforms of eukaryotic initiation factor 4E in Leishmania

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Highly efficient tandem affinity purification of trypanosome protein complexes based on a novel epitope combination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

The Genome of the African Trypanosome Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Regulation of cap-dependent translation by eIF4E inhibitory proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

eIF4E isoform 2 in Schizosaccharomyces pombe is a novel stress-response factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

GeneDB: a resource for prokaryotic and eukaryotic organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC/LC-MS/MS) for large-scale protein analysis: the yeast proteome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Life without transcriptional control? From fly to man and back again

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Evolutionary origin of SL-addition trans-splicing: still an enigma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Trypanosoma brucei RNA triphosphatase. Antiprotozoal drug target and guide to eukaryotic phylogeny

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Functional characterization of five eIF4E isoforms in Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Trypanosome capping enzymes display a novel two-domain structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

A signature for the HMG-1 box DNA-binding proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Mass spectrometry of mRNA cap 4 from trypanosomatids reveals two novel nucleosides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

New culture medium for maintenance of tsetse tissues and growth of trypanosomatids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 July 2018

Calmodulin is required for paraflagellar rod assembly and flagellum-cell body attachment in trypanosomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

Evolutionary conservation and diversification of the translation initiation apparatus in trypanosomatids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

High-throughput phenotyping using parallel sequencing of RNA interference targets in the African trypanosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

The four trypanosomatid eIF4E homologues fall into two separate groups, with distinct features in primary sequence and biological properties.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

Functional overlap between eIF4G isoforms in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

Evidence for a capping enzyme with specificity for the trypanosome spliced leader RNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

RNA regulons: coordination of post-transcriptional events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

eIF4E is a central node of an RNA regulon that governs cellular proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

The two eIF4A helicases in Trypanosoma brucei are functionally distinct.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

Novel and essential subunits in the 300-kilodalton nuclear cap binding complex of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

trans and cis splicing in trypanosomatids: mechanism, factors, and regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

eIF4G functionally differs from eIFiso4G in promoting internal initiation, cap-independent translation, and translation of structured mRNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

Stabilization of eukaryotic initiation factor 4E binding to the mRNA 5'-Cap by domains of eIF4G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

A novel protein targeting domain directs proteins to the anterior cytoplasmic face of the flagellar pocket in African trypanosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4135740

28 October 2018

A common pyrimidine-rich motif governs trans-splicing and polyadenylation of tubulin polycistronic pre-mRNA in trypanosomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24839125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Trypanosoma brucei encodes a bifunctional capping enzyme essential for cap 4 formation on the spliced leader RNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/24839125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

eIF4G and CBP80 share a common origin and similar domain organization: implications for the structure and function of eIF4G

1 reference

https://pubmed.ncbi.nlm.nih.gov/24839125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein transport and flagellum assembly dynamics revealed by analysis of the paralysed trypanosome mutant snl-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/24839125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

eIF4G dramatically enhances the binding of eIF4E to the mRNA 5'-cap structure

1 reference

https://pubmed.ncbi.nlm.nih.gov/24839125

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/EC.00071-14

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

30 July 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q34057091&oldid=1823216655"