(Q37786003)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

Epigenetics and transcriptional control in African trypanosomes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1

Gloria Rudenko

1 reference

23 August 2017

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20822495

8 July 2024

publication date

1 September 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

20 September 2010

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20822495

full work available at URL

8 July 2024

https://portlandpress.com/essaysbiochem/article-pdf/doi/10.1042/bse0480201/854090/bse0480201.pdf

file format

Portable Document Format

1 reference

8 July 2024

published in

Essays in Biochemistry

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

volume

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

page(s)

201-219

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20822495%20AND%20SRC:MED&resulttype=core&format=json

Eukaryotic evolution, changes and challenges

13 February 2020

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The trypanosome transcriptome is remodelled during differentiation but displays limited responsiveness within life stages

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Trypanosomal TBP functions with the multisubunit transcription factor tSNAP to direct spliced-leader RNA gene expression

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Characterization of a multisubunit transcription factor complex essential for spliced-leader RNA gene transcription in Trypanosoma brucei

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Transcription of Leishmania major Friedlin chromosome 1 initiates in both directions within a single region.

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Four histone variants mark the boundaries of polycistronic transcription units in Trypanosoma brucei

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The actin gene promoter of Trypanosoma brucei

21 January 2018

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What the genome sequence is revealing about trypanosome antigenic variation

21 January 2018

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Analysis of the VSG gene silent archive in Trypanosoma brucei reveals that mosaic gene expression is prominent in antigenic variation and is favored by archive substructure

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Telomeric expression sites are highly conserved in Trypanosoma brucei

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The architecture of variant surface glycoprotein gene expression sites in Trypanosoma brucei

21 January 2018

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Isolation and analysis of the genetic diversity of repertoires of VSG expression site containing telomeres from Trypanosoma brucei gambiense, T. b. brucei and T. equiperdum.

21 January 2018

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Control of variant surface glycoprotein gene-expression sites in Trypanosoma brucei

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Antigenic variation and allelic exclusion

21 January 2018

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Predominance of duplicative VSG gene conversion in antigenic variation in African trypanosomes

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Expression site activation in Trypanosoma brucei with three marked variant surface glycoprotein gene expression sites

21 January 2018

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Efficient transcription of a protein-coding gene from the RNA polymerase I promoter in transfected cells

21 January 2018

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RNA polymerase I-promoted HIS4 expression yields uncapped, polyadenylated mRNA that is unstable and inefficiently translated in Saccharomyces cerevisiae

21 January 2018

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The PARP promoter of Trypanosoma brucei is developmentally regulated in a chromosomal context.

21 January 2018

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Unravelling the procyclin coat of Trypanosoma brucei.

21 January 2018

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Position effect at S. cerevisiae telomeres: reversible repression of Pol II transcription

21 January 2018

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Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae.

21 January 2018

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Repression of polymerase I-mediated gene expression at Trypanosoma brucei telomeres

21 January 2018

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Deletion of a trypanosome telomere leads to loss of silencing and progressive loss of terminal DNA in the absence of cell cycle arrest

21 January 2018

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The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability

21 January 2018

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Phenotypic switching in Candida albicans is controlled by a SIR2 gene

21 January 2018

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Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites

21 January 2018

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Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

21 January 2018

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A sirtuin in the African trypanosome is involved in both DNA repair and telomeric gene silencing but is not required for antigenic variation.

21 January 2018

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A chromosomal SIR2 homologue with both histone NAD-dependent ADP-ribosyltransferase and deacetylase activities is involved in DNA repair in Trypanosoma brucei

21 January 2018

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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

21 January 2018

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Yeast Ku protein plays a direct role in telomeric silencing and counteracts inhibition by rif proteins.

21 January 2018

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Telomere length regulation and transcriptional silencing in KU80-deficient Trypanosoma brucei

21 January 2018

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RAP1 is essential for silencing telomeric variant surface glycoprotein genes in Trypanosoma brucei.

21 January 2018

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A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation

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Antigenic variation: extending the reach of telomeric silencing.

21 January 2018

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Genomic DNA methylation: the mark and its mediators

21 January 2018

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African trypanosomes contain 5-methylcytosine in nuclear DNA.

21 January 2018

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Base J: Discovery, Biosynthesis, and Possible Functions

21 January 2018

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Localization of the modified base J in telomeric VSG gene expression sites of Trypanosoma brucei

21 January 2018

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The telomeric GGGTTA repeats of Trypanosoma brucei contain the hypermodified base J in both strands

21 January 2018

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Intragenic DNA methylation alters chromatin structure and elongation efficiency in mammalian cells

21 January 2018

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JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

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Trypanosoma brucei variant surface glycoprotein regulation involves coupled activation/inactivation and chromatin remodeling of expression sites

21 January 2018

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The immunoglobulin mu enhancer core establishes local factor access in nuclear chromatin independent of transcriptional stimulation

21 January 2018

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Active VSG expression sites in Trypanosoma brucei are depleted of nucleosomes

21 January 2018

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Nucleosomes are depleted at the VSG expression site transcribed by RNA polymerase I in African trypanosomes

21 January 2018

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A novel ISWI is involved in VSG expression site downregulation in African trypanosomes

21 January 2018

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Functional analysis of the DNA-stimulated ATPase domain of yeast SWI2/SNF2.

21 January 2018

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Chromatin remodeling by ATP-dependent molecular machines.

21 January 2018

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A histone methyltransferase modulates antigenic variation in African trypanosomes.

21 January 2018

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Histone modifications in Trypanosoma brucei

21 January 2018

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Epigenetic regulation in African trypanosomes: a new kid on the block

21 January 2018

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Transcription in the yeast rRNA gene locus: distribution of the active gene copies and chromatin structure of their flanking regulatory sequences

21 January 2018

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The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription

21 January 2018

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NoRC-dependent nucleosome positioning silences rRNA genes

21 January 2018

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Actively transcribed rRNA genes in S. cerevisiae are organized in a specialized chromatin associated with the high-mobility group protein Hmo1 and are largely devoid of histone molecules.

21 January 2018

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Structure and function of ribosomal RNA gene chromatin

21 January 2018

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The epigenetics of rRNA genes: from molecular to chromosome biology

21 January 2018

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Subnuclear localization of the active variant surface glycoprotein gene expression site in Trypanosoma brucei.

21 January 2018

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Nuclear repositioning of the VSG promoter during developmental silencing in Trypanosoma brucei

21 January 2018

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Allelic inactivation regulates olfactory receptor gene expression

21 January 2018

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Interchromosomal interactions and olfactory receptor choice

21 January 2018

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Cohesin regulates VSG monoallelic expression in trypanosomes

21 January 2018

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A pol I transcriptional body associated with VSG mono-allelic expression in Trypanosoma brucei

21 January 2018

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The molecular karyotype of the megabase chromosomes of Trypanosoma brucei and the assignment of chromosome markers

21 January 2018

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Identification, purification and properties of clone-specific glycoprotein antigens constituting the surface coat ofTrypanosoma brucei

8 July 2024

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Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite

8 July 2024

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Differential RNA elongation controls the variant surface glycoprotein gene expression sites of Trypanosoma brucei

8 July 2024

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Ku is important for telomere maintenance, but not for differential expression of telomeric VSG genes, in African trypanosomes

8 July 2024

51

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Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast

8 July 2024

54

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Trypanosoma brucei variant-specific glycoprotein gene chromatin is sensitive to single-strand-specific endonuclease digestion

8 July 2024

64

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In situ analysis of a variant surface glycoprotein expression-site promoter region in Trypanosoma brucei

8 July 2024

65

1 reference

Unusual histone modifications in Trypanosoma brucei

8 July 2024

75

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Acetylation of histone H4K4 is cell cycle regulated and mediated by HAT3 in Trypanosoma brucei.

8 July 2024

77

1 reference

DNA rearrangements associated with multiple consecutive directed antigenic switches in Trypanosoma brucei

8 July 2024

86

1 reference

Blurring cis and trans in gene regulation

8 July 2024

89

1 reference

A ribosomal DNA promoter replacing the promoter of a telomeric VSG gene expression site can be efficiently switched on and off in T. brucei

8 July 2024

91

1 reference