(Q34058380)

30 July 2017

A mild impairment of mitochondrial electron transport has sex-specific effects on lifespan and aging in mice (English)

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30 July 2017

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Bryan G Hughes

1

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Siegfried Hekimi

object named as

Siegfried Hekimi

series ordinal

2

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language of work or name

English

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publication date

10 October 2011

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30 July 2017

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30 July 2017

6

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30 July 2017

10

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30 July 2017

e26116

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Creative Commons Attribution 4.0 International

30 July 2017

start time

10 October 2011

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3189954/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1+/- mouse mutants

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Mice deficient in both Mn superoxide dismutase and glutathione peroxidase-1 have increased oxidative damage and a greater incidence of pathology but no reduction in longevity

5 July 2018

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5 July 2018

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Overexpression of Mn superoxide dismutase does not increase life span in mice

5 July 2018

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Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels

5 July 2018

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Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice

5 July 2018

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Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

5 July 2018

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Early mitochondrial dysfunction in long-lived Mclk1+/- mice

5 July 2018

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Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice

5 July 2018

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Reduction in glutathione peroxidase 4 increases life span through increased sensitivity to apoptosis

5 July 2018

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Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: association with increased AGER1 expression

5 July 2018

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5 July 2018

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Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

5 July 2018

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Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency

5 July 2018

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5 July 2018

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5 July 2018

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Mitochondrial dysfunction and type 2 diabetes

5 July 2018

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Metabolism and function of coenzyme Q.

5 July 2018

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5 July 2018

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Constitutive knockout of Surf1 is associated with high embryonic lethality, mitochondrial disease and cytochrome c oxidase deficiency in mice

5 July 2018

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IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice

5 July 2018

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A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity

5 July 2018

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A mutant mitochondrial respiratory chain assembly protein causes complex III deficiency in patients with tubulopathy, encephalopathy and liver failure.

5 July 2018

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5 July 2018

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Influence of cholinergic system on motor learning during aging in mice

5 July 2018

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

5 July 2018

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Mutations of SURF-1 in Leigh disease associated with cytochrome c oxidase deficiency

5 July 2018

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Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex

5 July 2018

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Electron transfer by domain movement in cytochrome bc1

5 July 2018

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Cellular energy utilization and molecular origin of standard metabolic rate in mammals

5 July 2018

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Superoxide production by the mitochondrial respiratory chain

5 July 2018

1 reference

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Mitochondrial decay in hepatocytes from old rats: membrane potential declines, heterogeneity and oxidants increase

5 July 2018

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Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

5 July 2018

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Mice lacking both subunits of lysosomal beta-hexosaminidase display gangliosidosis and mucopolysaccharidosis

5 July 2018

1 reference

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Measuring nitric oxide and superoxide: rate constants for aconitase reactivity

5 July 2018

1 reference

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Structure and function of the mitochondrial bc1 complex. A mutational analysis of the yeast Rieske iron-sulfur protein

5 July 2018

1 reference

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Inbred SAM-P/10 as a Mouse Model of Spontaneous, Inherited Brain Atrophy

5 July 2018

1 reference

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Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Mitochondrial dysfunction as a cause of ageing

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Respiratory uncoupling in skeletal muscle delays death and diminishes age-related disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

The differential effects of superoxide anion, hydrogen peroxide and hydroxyl radical on cardiac mitochondrial oxidative phosphorylation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Do the serum oxidative stress biomarkers provide a reasonable index of the general oxidative stress status?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Mitochondrial oxidative phosphorylation is defective in the long-lived mutant clk-1.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Short and long-term motor skill learning in an accelerated rotarod training paradigm.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Rates of behavior and aging specified by mitochondrial function during development

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Control of oxidative phosphorylation by Complex I in rat liver mitochondria: implications for aging

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Metabolic mass, metabolic rate, caloric restriction, and aging in male Fischer 344 rats.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Energy thresholds in brain mitochondria. Potential involvement in neurodegeneration.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

Threshold effects and control of oxidative phosphorylation in nonsynaptic rat brain mitochondria.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3189954

The control of mitochondrial oxidations by complex III in rat muscle and liver mitochondria. Implications for our understanding of mitochondrial cytopathies in man

28 October 2018

1 reference

12 December 2020

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

1 reference

12 December 2020

Mitochondrial disorders

1 reference

12 December 2020

Decline in respiratory control ratio of rat liver mitochondria in old age

1 reference

12 December 2020

Increased longevity and refractoriness to Ca(2+)-dependent neurodegeneration in Surf1 knockout mice

1 reference

12 December 2020

1 reference

12 December 2020

Threshold effect and tissue specificity. Implication for mitochondrial cytopathies

1 reference

12 December 2020

Practical methodology of evaluation of mortality curves and detection of aging-related interventions

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0026116

Identifiers

DOI

1 reference

release_duagjpd5l5eehabec3ecvyasja

30 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/duagjpd5l5eehabec3ecvyasja

24 November 2022

mapped directly with Wikidata item

PMCID

3189954

1 reference

30 July 2017

1 reference

PubMed ID

22028811