Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34059286)
Watch
English
Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
title
Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
author
Boris Chernyak
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Peter M. Chumakov
series ordinal
5
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Alexandra Evstafieva
series ordinal
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
author name string
Anastasia A Khutornenko
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Vladimir V Roudko
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
Andrey B Vartapetian
series ordinal
4
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
language of work or name
English
0 references
publication date
21 June 2010
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
published in
Proceedings of the National Academy of Sciences of the United States of America
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
volume
107
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
issue
29
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
page(s)
12828-12833
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
cites work
Ubiquitin-independent p53 proteasomal degradation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Homeostatic functions of the p53 tumor suppressor: regulation of energy metabolism and antioxidant defense
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Versatile functions of p53 protein in multicellular organisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
The transcription stress response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
RPA and ATR link transcriptional stress to p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Oxygen-dependent regulation of mitochondrial respiration by hypoxia-inducible factor 1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
A pivotal role for p53: balancing aerobic respiration and glycolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
NRH:quinone oxidoreductase 2 and NAD(P)H:quinone oxidoreductase 1 protect tumor suppressor p53 against 20s proteasomal degradation leading to stabilization and activation of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Adriamycin-induced oxidative mitochondrial cardiotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Mitochondria: more than just a powerhouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Cytoprotective effects of hypoxia against cisplatin-induced tubular cell apoptosis: involvement of mitochondrial inhibition and p53 suppression.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
p53 ubiquitination: Mdm2 and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Transcription-independent pro-apoptotic functions of p53.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Manganese superoxide dismutase induces p53-dependent senescence in colorectal cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Hereditary paraganglioma/pheochromocytoma and inherited succinate dehydrogenase deficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Stress-induced activation of the p53 tumor suppressor in leukemia cells and normal lymphocytes requires mitochondrial activity and reactive oxygen species.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
A mechanism of ubiquitin-independent proteasomal degradation of the tumor suppressors p53 and p73
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Nuclear oncoprotein prothymosin alpha is a partner of Keap1: implications for expression of oxidative stress-protecting genes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Severe impairment of nucleotide synthesis through inhibition of mitochondrial respiration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
AIF deficiency compromises oxidative phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Crystal structure of quinone reductase 2 in complex with resveratrol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Mechanisms of hepatotoxicity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Differential gene expression in p53-mediated G(1) arrest of human fibroblasts after gamma-irradiation or N-phosphoacetyl-L-aspartate treatment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
p53: death star
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Redox regulation of p53 during hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Stress signals utilize multiple pathways to stabilize p53
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
The ARF/p53 pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
A p53-dependent S-phase checkpoint helps to protect cells from DNA damage in response to starvation for pyrimidine nucleotides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Isolation of human cell lines lacking mitochondrial DNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Inhibition of dihydroorotate dehydrogenase by the immunosuppressive agent leflunomide
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2919937
retrieved
5 July 2018
Reactive oxygen species production by the mitochondrial respiratory chain in isolated rat hepatocytes and liver mitochondria: studies using myxothiazol
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0910885107
retrieved
21 January 2018
Oligomycin, inhibitor of the F0 part of H+-ATP-synthase, suppresses the TNF-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1073%2FPNAS.0910885107
retrieved
21 January 2018
Sensing prothymosin alpha origin, mutations and conformation with monoclonal antibodies
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20566882
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
[Influence of prothymosin alpha and its mutants on activity of the p53 tumor suppressor]
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/20566882
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1073/PNAS.0910885107
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
ADS bibcode
2010PNAS..10712828K
0 references
PMC publication ID
2919937
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
PubMed publication ID
20566882
1 reference
stated in
Europe PubMed Central
PMC publication ID
2919937
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20566882%20AND%20SRC:MED&resulttype=core&format=json
retrieved
6 February 2020
ResearchGate publication ID
44691348
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit