(Q34065926)

30 July 2017

title

Short inverted repeats initiate gene amplification through the formation of a large DNA palindrome in mammalian cells (English)

1 reference

30 July 2017

Hisashi Tanaka

1

1 reference

30 July 2017

Stephen J Tapscott

series ordinal

2

1 reference

30 July 2017

Barbara J Trask

series ordinal

3

1 reference

30 July 2017

Meng-Chao Yao

series ordinal

4

1 reference

30 July 2017

language of work or name

English

0 references

publication date

11 June 2002

1 reference

Proceedings of the National Academy of Sciences of the United States of America

30 July 2017

published in

1 reference

30 July 2017

volume

99

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30 July 2017

issue

13

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30 July 2017

page(s)

8772-8777

1 reference

Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions

30 July 2017

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1 reference

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DNA ligase IV deficiency in mice leads to defective neurogenesis and embryonic lethality via the p53 pathway

5 July 2018

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Amplification of the human dihydrofolate reductase gene via double minutes is initiated by chromosome breaks

5 July 2018

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Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

5 July 2018

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Mechanisms of sod2 gene amplification in Schizosaccharomyces pombe

5 July 2018

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Genetic instabilities in human cancers

5 July 2018

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Warner-Lambert/Parke-Davis Award Lecture. Pathological and physiological double-strand breaks: roles in cancer, aging, and the immune system

5 July 2018

1 reference

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Urea improves efficiency of bisulphite-mediated sequencing of 5'-methylcytosine in genomic DNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

5 July 2018

1 reference

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Interstitial deletions and intrachromosomal amplification initiated from a double-strand break targeted to a mammalian chromosome

5 July 2018

1 reference

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A transposon-based strategy for sequencing repetitive DNA in eukaryotic genomes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Expression of fragile sites triggers intrachromosomal mammalian gene amplification and sets boundaries to early amplicons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Genomic instability and its role in neoplasia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

An intramolecular recombination mechanism for the formation of the rRNA gene palindrome of Tetrahymena thermophila

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Isolation of Chinese hamster cell mutants deficient in dihydrofolate reductase activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Isolation of the amplified dihydrofolate reductase domain from methotrexate-resistant Chinese hamster ovary cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

The multicopy appearance of a large inverted duplication and the sequence at the inversion joint suggest a new model for gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Formation of an inverted duplication can be an initial step in gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Structure of an inverted duplication formed as a first step in a gene amplification event: implications for a model of gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Charomids: cosmid vectors for efficient cloning and mapping of large or small restriction fragments

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Resistance to antimycin A in yeast by amplification of ADH4 on a linear, 42 kb palindromic plasmid.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Large inverted duplications are associated with gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

The controlling sequence for site-specific chromosome breakage in Tetrahymena.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Direct and inverted DNA repeats associated with P-glycoprotein gene amplification in drug resistant Leishmania.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Improved vectors for stable expression of foreign genes in mammalian cells by use of the untranslated leader sequence from EMC virus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Fusions near telomeres occur very early in the amplification of CAD genes in Syrian hamster cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=124374

Biased distribution of inverted and direct Alus in the human genome: implications for insertion, exclusion, and genome stability.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132275999

Chromosomal rearrangements occur in S. cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132275999

Structure of ribosomal DNA in Physarum polycephalum

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132275999

The macronuclear ribosomal DNA of Tetrahymena pyriformis is a palindrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132275999

Short inverted repeats at a free end signal large palindromic DNA formation in Tetrahymena

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132275999

Induction of large DNA palindrome formation in yeast: implications for gene amplification and genome stability in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.132275999

The Mre11 complex is required for repair of hairpin-capped double-strand breaks and prevention of chromosome rearrangements

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12060719

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.132275999

1 reference

30 July 2017

0 references

1 reference

30 July 2017

1 reference