(Q34082684)

30 July 2017

title

Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation (English)

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30 July 2017

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17

Leroy Hood

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Gerold Schmitt-Ulms

14

object named as

Gerold Schmitt-Ulms

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30 July 2017

David Westaway

1

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30 July 2017

Sacha Genovesi

2

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30 July 2017

Nathalie Daude

3

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30 July 2017

Rebecca Brown

4

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30 July 2017

Agnes Lau

5

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30 July 2017

Inyoul Lee

6

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30 July 2017

Charles E Mays

7

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30 July 2017

Janaky Coomaraswamy

8

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30 July 2017

Brenda Canine

9

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30 July 2017

Rose Pitstick

10

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30 July 2017

Allen Herbst

11

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30 July 2017

Jing Yang

12

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30 July 2017

Kerry W S Ko

13

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30 July 2017

Stephen J Dearmond

15

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30 July 2017

Debbie McKenzie

16

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30 July 2017

George A Carlson

18

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30 July 2017

publication date

17 November 2011

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30 July 2017

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30 July 2017

volume

7

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30 July 2017

issue

11

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30 July 2017

page(s)

e1002391

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Creative Commons Attribution 4.0 International

30 July 2017

copyright license

start time

17 November 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Conserved stress-protective activity between prion protein and Shadoo

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Peripheral protein quality control removes unfolded CFTR from the plasma membrane

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5 July 2018

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Agent-specific Shadoo responses in transmissible encephalopathies

5 July 2018

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Generating a prion with bacterially expressed recombinant prion protein

5 July 2018

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Interactome analyses identify ties of PrP and its mammalian paralogs to oligomannosidic N-glycans and endoplasmic reticulum-derived chaperones

5 July 2018

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Frequent missense and insertion/deletion polymorphisms in the ovine Shadoo gene parallel species-specific variation in PrP.

5 July 2018

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Comparative prion disease gene expression profiling using the prion disease mimetic, cuprizone

5 July 2018

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Shadoo (Sprn) and prion disease incubation time in mice

5 July 2018

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Prion protein library of recombinant constructs for structural biology

5 July 2018

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5 July 2018

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Association of a null allele of SPRN with variant Creutzfeldt-Jakob disease

5 July 2018

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A general model of prion strains and their pathogenicity

5 July 2018

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The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections

5 July 2018

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5 July 2018

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Cortical neuronal and glial pathology in TgTauP301L transgenic mice: neuronal degeneration, memory disturbance, and phenotypic variation

5 July 2018

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Dissociated phenotypes in presenilin transgenic mice define functionally distinct gamma-secretases

5 July 2018

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Synthetic mammalian prions

5 July 2018

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Murine scrapie infection causes an abnormal germinal centre reaction in the spleen

5 July 2018

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Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein

5 July 2018

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Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme

5 July 2018

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Scrapie strains maintain biological phenotypes on propagation in a cell line in culture

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Strain-specified relative conformational stability of the scrapie prion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

PrP(Sc) typing by N-terminal sequencing and mass spectrometry.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Eight prion strains have PrP(Sc) molecules with different conformations

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

A conformational transition at the N terminus of the prion protein features in formation of the scrapie isoform

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

5 July 2018

1 reference

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High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Observations on oligodendrocyte degeneration, the resolution of status spongiosus and remyelination in cuprizone intoxication in mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Mice devoid of PrP are resistant to scrapie

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

5 July 2018

1 reference

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In-vitro growth of pieces of brain from scrapie-affected mice

5 July 2018

1 reference

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Clinical and Histological Observations on Cuprizonc Toxicity and Scrapie in Mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

A comparison of the biochemical changes induced in mouse brain by cuprizone toxicity and by scrapie infection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Genetics and polymorphism of the mouse prion gene complex: control of scrapie incubation time

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Distinct prion proteins in short and long scrapie incubation period mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

A cellular gene encodes scrapie PrP 27-30 protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Identification of glycoinositol phospholipid linked and truncated forms of the scrapie prion protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

The Scrapie Agent In Vitro

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

N-terminal truncation of the scrapie-associated form of PrP by lysosomal protease(s): implications regarding the site of conversion of PrP to the protease-resistant state

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Are Sinc and the PrP gene congruent? Evidence from PrP gene analysis in Sinc congenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Synthesis and trafficking of prion proteins in cultured cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Regional mapping of prion proteins in brain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Biochemical and physical properties of the prion protein from two strains of the transmissible mink encephalopathy agent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Chimeric prion protein expression in cultured cells and transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Mice with gene targetted prion protein alterations show that Prnp, Sinc and Prni are congruent

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Spongiform encephalopathy induced in rats and guinea pigs by cuprizone

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Release of the cellular prion protein from cultured cells after loss of its glycoinositol phospholipid anchor

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Microglial/macrophage accumulation during cuprizone-induced demyelination in C57BL/6 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Prion clearance in bigenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Genetic analysis of the SPRN gene in ruminants reveals polymorphisms in the alanine-rich segment of shadoo protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

An optimized freeze-squeeze method for the recovery of DNA fragments from agarose gels

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Antibodies inhibit prion propagation and clear cell cultures of prion infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1002391

Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3219720

Strain characterization of natural sheep scrapie and comparison with BSE

28 October 2018

1 reference

12 December 2020

Overexpression of Shadoo protein in transgenic mice does not impact the pathogenesis of scrapie

1 reference

12 December 2020

Linkage of prion protein and scrapie incubation time genes

1 reference

12 December 2020

Transmissible spongiform encephalopathy strain-associated diversity of N-terminal proteinase K cleavage sites of PrP(Sc) from scrapie-infected and bovine spongiform encephalopathy-infected mice

1 reference

12 December 2020

10.1371/JOURNAL.PPAT.1002391

Identifiers

DOI

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30 July 2017

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30 July 2017

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