(Q34092461)

31 July 2017

Ras-mediated activation of the TORC2-PKB pathway is critical for chemotaxis (English)

1 reference

31 July 2017

TORC2 complex binding

1 reference

Gene Ontology release 2020-05-02

1 reference

6

Peter N Devreotes

1 reference

31 July 2017

Huaqing Cai

1

1 reference

31 July 2017

Satarupa Das

2

1 reference

31 July 2017

Yoichiro Kamimura

3

1 reference

31 July 2017

Yu Long

4

1 reference

31 July 2017

Carole A Parent

5

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 July 2010

1 reference

31 July 2017

Journal of Cell Biology

1 reference

31 July 2017

190

1 reference

31 July 2017

233-245

1 reference

31 July 2017

2

1 reference

describes a project that uses

31 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2930282/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Phosphoinositide-dependent protein kinase (PDK) activity regulates phosphatidylinositol 3,4,5-trisphosphate-dependent and -independent protein kinase B activation and chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Chemotaxis: finding the way forward with Dictyostelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Spatiotemporal regulation of Ras activity provides directional sensing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

PIP3-independent activation of TorC2 and PKB at the cell's leading edge mediates chemotaxis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Ras oncogenes: split personalities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

The TSC1-TSC2 complex is required for proper activation of mTOR complex 2

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Navigating through models of chemotaxis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

G protein-independent Ras/PI3K/F-actin circuit regulates basic cell motility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Navigating signaling networks: chemotaxis in Dictyostelium discoideum

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Localized Ras signaling at the leading edge regulates PI3K, cell polarity, and directional cell movement

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

A rapid and efficient method to generate multiple gene disruptions in Dictyostelium discoideum using a single selectable marker and the Cre-loxP system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Chemoattractant-induced Ras activation during Dictyostelium aggregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Receptor-mediated regulation of PI3Ks confines PI(3,4,5)P3 to the leading edge of chemotaxing cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Ras superfamily monomeric G proteins in carcinoma cell motility

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

The phosphoinositide 3-kinase pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

A novel Ras-interacting protein required for chemotaxis and cyclic adenosine monophosphate signal relay in Dictyostelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Chemoattractant-mediated transient activation and membrane localization of Akt/PKB is required for efficient chemotaxis to cAMP in Dictyostelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Dynamic distribution of chemoattractant receptors in living cells during chemotaxis and persistent stimulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Phosphatidylinositol-3-OH kinase as a direct target of Ras

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

FMLP activates Ras and Raf in human neutrophils. Potential role in activation of MAP kinase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Chemoattractant and GTP gamma S-mediated stimulation of adenylyl cyclase in Dictyostelium requires translocation of CRAC to membranes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2930282

Spatial and temporal regulation of 3-phosphoinositides by PI 3-kinase and PTEN mediates chemotaxis

5 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

Tumor suppressor PTEN mediates sensing of chemoattractant gradients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

Receptor-mediated activation of heterotrimeric G-proteins in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

Assays for chemotaxis and chemoattractant-stimulated TorC2 activation and PKB substrate phosphorylation in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

Group migration and signal relay in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

Adenylyl cyclase localization regulates streaming during chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

A novel Akt/PKB-related kinase is essential for morphogenesis in Dictyostelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

A Lim protein involved in the progression of cytokinesis and regulation of the mitotic spindle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

An extrachromosomal, inducible expression system for Dictyostelium discoideum

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201001129

Chemotactic peptide-induced activation of Ras in human neutrophils is associated with inhibition of p120-GAP activity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20660630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

G protein signaling events are activated at the leading edge of chemotactic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20660630

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1083/JCB.201001129

1 reference

31 July 2017

1 reference

31 July 2017

1 reference