(Q34098353)

31 July 2017

1 reference

title

Neurotrophin small-molecule mimetics (English)

1 reference

31 July 2017

Y Xie

1

1 reference

31 July 2017

F M Longo

series ordinal

2

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31 July 2017

publication date

1 January 2000

1 reference

Progress in Brain Research

31 July 2017

published in

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31 July 2017

volume

128

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31 July 2017

page(s)

333-347

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Kinetics of trkA tyrosine kinase activity and inhibition by K-252a

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

p75NTR: A study in contrasts

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Disruption of NGF binding to the low affinity neurotrophin receptor p75LNTR reduces NGF binding to TrkA on PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Solution Structure and Internal Motion of a Bioactive Peptide Derived from Nerve Growth Factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

NGF and neurotrophin-3 both activate TrkA on sympathetic neurons but differentially regulate survival and neuritogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Differential effects of the protein kinase inhibitor K-252a on the in vitro survival of chick embryonic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

CEP-1347/KT7515, a JNK pathway inhibitor, supports the in vitro survival of chick embryonic neurons.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nerve growth factor: structure/function relationships

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

p75NTR and the concept of cellular dependence: seeing how the other half die.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Induction of NGF by isoproterenol, 4-methylcatechol and serum occurs by three distinct mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophin receptors: mediators of life and death

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

TrkA cross-linking mimics neuronal responses to nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

The role of neuronal growth factors in neurodegenerative disorders of the human brain

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

1 reference

7 January 2021

Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophic factors prevent the death of CNS neurons after spinal cord lesions in newborn rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nerve growth factor: two receptors, multiple functions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Induction of cell death by endogenous nerve growth factor through its p75 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nonpeptidic ligands for peptide and protein receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophin signaling via Trks and p75.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Effect of AIT-082, a purine analog, on working memory in normal and aged mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

AIT-082, a novel purine derivative with neuroregenerative properties.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Early events in neurotrophin signalling via Trk and p75 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Cellular delivery of neurotrophin-3 promotes corticospinal axonal growth and partial functional recovery after spinal cord injury.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Guanosine enhances NGF-stimulated neurite outgrowth in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Pharmacology of neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Emerging approaches in the molecular design of receptor-selective peptide ligands: conformational, topographical and dynamic considerations

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophic factors: from structure-function studies to designing effective therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Signal transduction by the neurotrophin receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Dictyophorines A and B, two stimulators of NGF-synthesis from the mushroom Dictyophora indusiata

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Efficacy in drug receptor theory: outdated concept or under-valued tool?

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Therapeutic peptides and peptidomimetics

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Talpha1-tubulin mRNA expression, and promote axonal regeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

K-252b selectively potentiates cellular actions and trk tyrosine phosphorylation mediated by neurotrophin-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neutralizing intraspinal nerve growth factor blocks autonomic dysreflexia caused by spinal cord injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Two restricted sites on the surface of the nerve growth factor molecule independently determine specific TrkA receptor binding and activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Small peptide mimics of nerve growth factor bind TrkA receptors and affect biological responses

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nerve growth factor: from neurotrophin to neurokine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

New directions in pain research: molecules to maladies

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Evaluation of partial beta-adrenoceptor agonist activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Minimized hormones grow in stature

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Synthetic NGF peptide derivatives prevent neuronal death via a p75 receptor-dependent mechanism.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nerve growth factor- and neurotrophin-3-induced changes in nociceptive threshold and the release of substance P from the rat isolated spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Optimal nerve growth factor trophic signals mediated by synergy of TrkA and p75 receptor-specific ligands.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Motoneuron apoptosis is blocked by CEP-1347 (KT 7515), a novel inhibitor of the JNK signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Structural determinants of neurotrophin action.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

New protein fold revealed by a 2.3-A resolution crystal structure of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

AIT-082, a unique purine derivative, enhances nerve growth factor mediated neurite outgrowth from PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Intraventricular infusion of nerve growth factor as the cause of sympathetic fiber sprouting in sensory ganglia

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

In vitro and in vivo effects of a peptide mimetic (SC-47643) of RGD as an antiplatelet and antithrombotic agent

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Oral administration of idebenone induces nerve growth factor in the brain and improves learning and memory in basal forebrain-lesioned rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Peptide antagonists of the human estrogen receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Stimulation of neurotrophic factor secretion from 1321N1 human astrocytoma cells by novel diterpenoids, scabronines A and G.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophins promote regeneration of sensory axons in the adult rat spinal cord

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Distinct neurite outgrowth signaling pathways converge on ERK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Partial agonism: mechanisms based on ligand-receptor interactions and on stimulus-response coupling

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Evidence for nerve growth factor-potentiating activities of the nonpeptidic compound SR 57746A in PC12 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Induction of apoptosis by the low-affinity NGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Zinc alters conformation and inhibits biological activities of nerve growth factor and related neurotrophins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Reciprocal modulation of TrkA and p75NTR affinity states is mediated by direct receptor interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Intracranial delivery of recombinant nerve growth factor: release kinetics and protein distribution for three delivery systems

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

A TrkA-selective, fast internalizing nerve growth factor-antibody complex induces trophic but not neuritogenic signals

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Intracellular signaling pathways activated by neurotrophic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophin-3 prevents death of axotomized Clarke's nucleus neurons in adult rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Stimulation of nerve growth factor synthesis/secretion by propentofylline in cultured mouse astroglial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Neurotrophic molecules: strategies for designing effective therapeutic molecules in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

PD 90780, a non peptide inhibitor of nerve growth factor's binding to the P75 NGF receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Experimental strategies to promote axonal regeneration after traumatic central nervous system injury

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Stimulation of nerve growth factor synthesis/secretion by 1,4-benzoquinone and its derivatives in cultured mouse astroglial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Suppression of p140trkA does not abolish nerve growth factor-mediated rescue of serum-free PC12 cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

A small, nonpeptidyl mimic of granulocyte-colony-stimulating factor [see commetns].

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Characterization of histidine residues essential for receptor binding and activity of nerve growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Characterization of the recombinant extracellular domain of the neurotrophin receptor TrkA and its interaction with nerve growth factor (NGF)

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Increased potency of an erythropoietin peptide mimetic through covalent dimerization

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Nerve growth factor (NGF) loop 4 dimeric mimetics activate ERK and AKT and promote NGF-like neurotrophic effects

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Orally active NGF synthesis stimulators: potential therapeutic agents in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Early BDNF, NT-3, and NT-4 signaling events

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Discovery of a Small Molecule Insulin Mimetic with Antidiabetic Activity in Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

K-252 compounds: modulators of neurotrophin signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

The in vitro biological effect of nerve growth factor is inhibited by synthetic peptides

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

Response of rubrospinal and corticospinal neurons to injury and neurotrophins

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6123%2800%2928030-8

7 January 2021

10.1016/S0079-6123(00)28030-8

Identifiers

DOI

1 reference

31 July 2017

1 reference