(Q34102615)

31 July 2017

title

Peroxisome proliferator-activated receptor delta is a specific sensor for teratogenic valproic acid derivatives (English)

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31 July 2017

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ChEBI release 2020-05-28

Lampen A

1

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31 July 2017

Carlberg C

series ordinal

2

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31 July 2017

Nau H

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

1 November 2001

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European Journal of Pharmacology

31 July 2017

published in

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31 July 2017

volume

431

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31 July 2017

issue

1

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31 July 2017

page(s)

25-33

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Further branching of valproate-related carboxylic acids reduces the teratogenic activity, but not the anticonvulsant effect

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901423-6

Studies on the teratogen pharmacophore of valproic acid analogues: evidence of interactions at a hydrophobic centre.

7 January 2021

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Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

7 January 2021

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Possible mechanisms of valproate in migraine prophylaxis

7 January 2021

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The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling

7 January 2021

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Spina bifida aperta induced by valproic acid and by all-trans-retinoic acid in the mouse: distinct differences in morphology and periods of sensitivity

7 January 2021

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Anticonvulsant and neurotoxic activities of twelve analogues of valproic acid

7 January 2021

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

7 January 2021

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Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor

7 January 2021

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The enantiomers of the valproic acid analogue 2-n-propyl-4-pentynoic acid (4-yn-VPA): asymmetric synthesis and highly stereoselective teratogenicity in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0014-2999%2801%2901423-6

PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs

7 January 2021

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Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators

7 January 2021

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DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5'-flanking region

7 January 2021

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Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers

7 January 2021

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Differential expression and activation of a family of murine peroxisome proliferator-activated receptors

7 January 2021

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Fatty acids and eicosanoids regulate gene expression through direct interactions with peroxisome proliferator-activated receptors alpha and gamma

7 January 2021

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New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: activation of the peroxisomal proliferator-activated receptor (PPARdelta).

7 January 2021

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Ligand selectivity of the peroxisome proliferator-activated receptor alpha

7 January 2021

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The RXR heterodimers and orphan receptors

7 January 2021

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Developmental toxicity and structure-activity relationships of aliphatic acids, including dose-response assessment of valproic acid in mice and rats

7 January 2021

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Valproic Acid-Induced Neural Tube Defects in Mouse and Human: Aspects of Chirality, Alternative Drug Development, Pharmacokinetics and Possible Mechanisms

7 January 2021

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Physical-chemical model for the entry of water-insoluble compounds into cells. Studies of fatty acid uptake by the liver

7 January 2021

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Fatty acid-binding protein in small intestine. Identification, isolation, and evidence for its role in cellular fatty acid transport

7 January 2021

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A selective peroxisome proliferator-activated receptor delta agonist promotes reverse cholesterol transport

7 January 2021

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Ligand-triggered stabilization of vitamin D receptor/retinoid X receptor heterodimer conformations on DR4-type response elements

7 January 2021

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Peroxisome proliterator-activated receptors, orphans with ligands and functions

7 January 2021

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Valproate: a new drug in migraine prophylaxis.

7 January 2021

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Induction of differentiation in F9 cells and activation of peroxisome proliferator-activated receptor delta by valproic acid and its teratogenic derivatives.

7 January 2021

1 reference

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Molecular recognition of fatty acids by peroxisome proliferator-activated receptors

7 January 2021

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10.1016/S0014-2999(01)01423-6

7 January 2021

Identifiers

DOI

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31 July 2017

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