(Q34103369)

31 July 2017

Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT) (English)

1 reference

31 July 2017

1 reference

0 references

Wagner EF

6

0 references

author name string

Behrens A

1

1 reference

31 July 2017

Sabapathy K

2

1 reference

31 July 2017

Graef I

3

1 reference

31 July 2017

Cleary M

4

1 reference

31 July 2017

Crabtree GR

5

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 February 2001

1 reference

Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

1 reference

31 July 2017

98

1 reference

31 July 2017

1769-1774

1 reference

31 July 2017

4

1 reference

c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1.

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

JNK is required for effector T-cell function but not for T-cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Regulation of c-Jun NH(2)-terminal kinase (Jnk) gene expression during T cell activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Tumor necrosis factor receptor and Fas signaling mechanisms.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

5 July 2018

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Control of cell cycle progression by c-Jun is p53 dependent

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Requirement for transcription factor NFAT in interleukin-2 expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Differentiation of CD4+ T cells to Th1 cells requires MAP kinase JNK2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

The transcription factor NFAT4 is involved in the generation and survival of T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Solution structure of the core NFATC1/DNA complex

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

The transcription factor NF-ATc1 regulates lymphocyte proliferation and Th2 cytokine production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Nuclear accumulation of NFAT4 opposed by the JNK signal transduction pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Transcription factors of the NFAT family: regulation and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Tumor necrosis factor alpha-induced activation of c-jun N-terminal kinase is mediated by TRAF2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Unusual Rel-like architecture in the DNA-binding domain of the transcription factor NFATc

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Activation of SAPK/JNK by TNF receptor 1 through a noncytotoxic TRAF2-dependent pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Induction of c-fos expression through JNK-mediated TCF/Elk-1 phosphorylation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Selective interaction of JNK protein kinase isoforms with transcription factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Hyperproliferation and dysregulation of IL-4 expression in NF-ATp-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Activation of ternary complex factor Elk-1 by stress-activated protein kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Characterization of the nuclear and cytoplasmic components of the lymphoid-specific nuclear factor of activated T cells (NF-AT) complex.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

p21ras and calcineurin synergize to regulate the nuclear factor of activated T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

The stress-activated protein kinase subfamily of c-Jun kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Activation of cAMP and mitogen responsive genes relies on a common nuclear factor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Identification of the immunophilins capable of mediating inhibition of signal transduction by cyclosporin A and FK506: roles of calcineurin binding and cellular location

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Identification of a putative regulator of early T cell activation genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Contingent genetic regulatory events in T lymphocyte activation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

5 July 2018

https://pubmed.ncbi.nlm.nih.gov/11172026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

Nuclear factor of activated T cells contains Fos and Jun.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development.

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Reprogramming the signalling requirement for AP-1 (activator protein-1) activation during differentiation of precursor CD4+ T-cells into effector Th1 and Th2 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Defects in actin-cap formation in Vav-deficient mice implicate an actin requirement for lymphocyte signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

c-Jun is essential for normal mouse development and hepatogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Defective T Cell Differentiation in the Absence of Jnk1

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Generation of normal T and B lymphocytes by c-jun deficient embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=29332

A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.98.4.1769

The regulation of CD4 T cell differentiation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11172026

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.98.4.1769

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference