(Q34117494)

31 July 2017

title

p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells (English)

1 reference

31 July 2017

0 references

Stephen James Griffiths

Stephen J Griffiths

6

0 references

Natalie E Riddell

Natalie E Riddell

3

0 references

Sian M Henson

Sian M Henson

1

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Anna Katharina Simon

Anna Katharina Simon

9

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Arne N Akbar

Arne N Akbar

11

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Sharon Tooze

Sharon A Tooze

10

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author name string

Alessio Lanna

2

1 reference

31 July 2017

Ornella Franzese

4

1 reference

31 July 2017

Richard Macaulay

5

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31 July 2017

Daniel J Puleston

7

1 reference

31 July 2017

Alexander Scarth Watson

8

1 reference

31 July 2017

language of work or name

English

0 references

publication date

1 August 2014

1 reference

Journal of Clinical Investigation

31 July 2017

published in

1 reference

31 July 2017

volume

124

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31 July 2017

issue

9

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31 July 2017

page(s)

4004-4016

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Metabolic regulation of T lymphocytes

31 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Molecular signature of CD8+ T cell exhaustion during chronic viral infection.

5 July 2018

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5 July 2018

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5 July 2018

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Increased mitochondrial mass characterizes the survival defect of HIV-specific CD8(+) T cells

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Alternative p38 activation pathway mediated by T cell receptor-proximal tyrosine kinases

5 July 2018

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5 July 2018

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A DNA damage checkpoint response in telomere-initiated senescence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Reversal of human cellular senescence: roles of the p53 and p16 pathways

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Lack of proliferative capacity of human effector and memory T cells expressing killer cell lectinlike receptor G1 (KLRG1)

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Telomeres in T and B cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Mammalian MAP kinase signalling cascades

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Structures containing Atg9A and the ULK1 complex independently target depolarized mitochondria at initial stages of Parkin-mediated mitophagy.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Reversal of functional defects in highly differentiated young and old CD8 T cells by PDL blockade

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Reversible senescence in human CD4+CD45RA+CD27- memory T cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Are senescence and exhaustion intertwined or unrelated processes that compromise immunity?

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Cytomegalovirus infection reduces telomere length of the circulating T cell pool.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Four functionally distinct populations of human effector-memory CD8+ T lymphocytes.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Direct measurement of T cell subset kinetics in vivo in elderly men and women

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Proliferative arrest and cell cycle regulation in CD8(+)CD28(-) versus CD8(+)CD28(+) T cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Memory T cells constitute a subset of the human CD8+CD45RA+ pool with distinct phenotypic and migratory characteristics.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4151208

Genetic manipulation of telomerase in HIV-specific CD8+ T cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization

28 October 2018

1 reference

12 December 2020

Circulating Tumor-reactive CD8(+) T cells in melanoma patients contain a CD45RA(+)CCR7(-) effector subset exerting ex vivo tumor-specific cytolytic activity

1 reference

12 December 2020

The road to recovery: translating PD-1 biology into clinical benefit

1 reference

12 December 2020

Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI75051

1 reference

31 July 2017

1 reference

31 July 2017

1 reference