(Q34117841)

31 July 2017

title

Further support to the uncoupling-to-survive theory: the genetic variation of human UCP genes is associated with longevity (English)

1 reference

31 July 2017

1 reference

Francesco De Rango

3

0 references

Alberto Montesanto

object named as

Alberto Montesanto

4

0 references

Giuseppina Rose

object named as

Giuseppina Rose

1

0 references

author name string

Paolina Crocco

2

1 reference

31 July 2017

Giuseppe Passarino

5

1 reference

31 July 2017

language of work or name

English

0 references

publication date

27 December 2011

1 reference

31 July 2017

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31 July 2017

volume

6

1 reference

31 July 2017

issue

12

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31 July 2017

page(s)

e29650

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

27 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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5 July 2018

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UCP-2 and UCP-3 proteins are differentially regulated in pancreatic beta-cells

5 July 2018

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Mitochondrial uncoupling proteins--what is their physiological role?

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Transgenic mice with a reduced core body temperature have an increased life span

5 July 2018

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Regulation of insulin secretion by uncoupling protein

5 July 2018

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Mitochondrial UCP4 mediates an adaptive shift in energy metabolism and increases the resistance of neurons to metabolic and oxidative stress

5 July 2018

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Uncoupling protein homologs may provide a link between mitochondria, metabolism and lifespan

5 July 2018

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5 July 2018

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Energy metabolism and oxidative stress: impact on the metabolic syndrome and the aging process

5 July 2018

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5 July 2018

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Mitochondrial uncoupling proteins in the CNS: in support of function and survival.

5 July 2018

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Sarcopenia of aging and its metabolic impact

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells.

5 July 2018

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A note on exact tests of Hardy-Weinberg equilibrium

5 July 2018

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Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Ageing, oxidative stress, and mitochondrial uncoupling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Haploview: analysis and visualization of LD and haplotype maps

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Brown adipose tissue: function and physiological significance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Uncoupling protein 2: a novel player in neuroprotection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Mutational analysis of the UCP2 core promoter and relationships of variants with obesity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Invited review: Aging and energy balance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Mitochondrial uncoupling protein 2 in the central nervous system: neuromodulator and neuroprotector

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Mitochondria in cell death: novel targets for neuroprotection and cardioprotection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Oxidative damage and phospholipid fatty acyl composition in skeletal muscle mitochondria from mice underexpressing or overexpressing uncoupling protein 3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

UCP5/BMCP1 transcript isoforms in human skeletal muscle: relationship of the short-insert isoform with lipid oxidation and resting metabolic rates

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Score tests for association between traits and haplotypes when linkage phase is ambiguous

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Superoxide activates mitochondrial uncoupling proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Genetic and physiological analysis of the role of uncoupling proteins in human energy homeostasis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Frailty in older adults: evidence for a phenotype

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Uncoupling to survive? The role of mitochondrial inefficiency in ageing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Energy metabolism in uncoupling protein 3 gene knockout mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Skeletal muscle UCP3 and UCP2 gene expression in response to inhibition of free fatty acid flux through mitochondrial beta-oxidation.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Association between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabolism/obesity in Pima indians.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Functional characterization of a Drosophila mitochondrial uncoupling protein

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Characterization of survival and phenotype throughout the life span in UCP2/UCP3 genetically altered mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Sex and age specificity of susceptibility genes modulating survival at old age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Trend tests for case-control studies of genetic markers: power, sample size and robustness

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Improving strategies for detecting genetic patterns of disease susceptibility in association studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Ala55Val polymorphism on UCP2 gene predicts greater weight loss in morbidly obese patients undergoing gastric banding

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Uncoupling protein-2 polymorphisms in type 2 diabetes, obesity, and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Association of the ins/del polymorphisms of uncoupling protein 2 (UCP2) with BMI in a Korean population

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Uncoupling proteins in human heart

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Uncoupling protein-2: evidence for its function as a metabolic regulator

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Resting metabolic rate and respiratory quotient in human longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

A novel polymorphism in the proximal UCP3 promoter region: effect on skeletal muscle UCP3 mRNA expression and obesity in male non-diabetic Pima Indians

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Skeletal muscle uncoupling protein 3 expression is a determinant of energy expenditure in Pima Indians.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

The effect of UCP3 overexpression on mitochondrial ROS production in skeletal muscle of young versus aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

The brain uncoupling protein UCP4 attenuates mitochondrial toxin-induced cell death: role of extracellular signal-regulated kinases in bioenergetics adaptation and cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

A homozygous genetic variant of mitochondrial uncoupling protein 4 exerts protection against the occurrence of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

A homozygous genetic variant of mitochondrial uncoupling protein 4 affects the occurrence of leukoaraiosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Transcription of the human uncoupling protein 3 gene is governed by a complex interplay between the promoter and intronic sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

Linkage Between Markers in the Vicinity of the Uncoupling Protein 2 Gene and Resting Metabolic Rate in Humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029650

UCP2 -866G/A and Ala55Val, and UCP3 -55C/T polymorphisms in association with type 2 diabetes susceptibility: a meta-analysis study.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Constitutive UCP3 overexpression at physiological levels increases mouse skeletal muscle capacity for fatty acid transport and oxidation

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

Energy metabolism of adipose tissue--physiological aspects and target in obesity treatment.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3246500

The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency

28 October 2018

1 reference

12 December 2020

To: Saleh MC, Wheeler MB, Chan CB (2002) Uncoupling protein-2: evidence for its function as a metabolic regulator. Diabetologia 45:174-187

1 reference

12 December 2020

A common polymorphism in the UCP3 promoter influences hand grip strength in elderly people

1 reference

12 December 2020

Two variants located in the upstream enhancer region of human UCP1 gene affect gene expression and are correlated with human longevity

1 reference

12 December 2020

Bacterial lipopolysaccharide induces uncoupling protein-2 expression in hepatocytes by a tumor necrosis factor-alpha-dependent mechanism

1 reference

12 December 2020

A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation

1 reference

12 December 2020

Impact of the v/v 55 polymorphism of the uncoupling protein 2 gene on 24-h energy expenditure and substrate oxidation

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029650

Identifiers

DOI

1 reference

31 July 2017

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1 reference

31 July 2017

1 reference