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Mitochondria in cell death: novel targets for neuroprotection and cardioprotection
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
review article
1 reference
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Europe PubMed Central
title
Mitochondria in cell death: novel targets for neuroprotection and cardioprotection
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
main subject
mitochondrion
1 reference
based on heuristic
inferred from title
cell death
1 reference
based on heuristic
inferred from title
author
Guido Kroemer
series ordinal
2
object named as
Guido Kroemer
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Mark Mattson
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1
object named as
Mark P Mattson
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
publication date
1 May 2003
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
published in
Trends in Molecular Medicine
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stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
issue
5
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
page(s)
196-205
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Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
cites work
Mitochondria, AIF and caspases--rivaling for cell death execution.
1 reference
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Crossref
reference URL
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Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?
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Permeability transition-independent release of mitochondrial cytochrome c induced by valinomycin
1 reference
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Cytoprotective role of Ca2+- activated K+ channels in the cardiac inner mitochondrial membrane
1 reference
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reference URL
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Apoptotic and antiapoptotic mechanisms in stroke.
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reference URL
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7 January 2021
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Mitochondrial participation in ischemic and traumatic neural cell death
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Neuroprotection by the inhibition of apoptosis
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7 January 2021
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Evidence for the involvement of Par-4 in ischemic neuron cell death
1 reference
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reference URL
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Activation of mitochondrial ATP-dependent potassium channels protects neurons against ischemia-induced death by a mechanism involving suppression of Bax translocation and cytochrome c release
1 reference
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Liposome-mediated transfer of the bcl-2 gene results in neuroprotection after in vivo transient focal cerebral ischemia in an animal model.
1 reference
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reference URL
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7 January 2021
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Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Excitotoxicity and mitochondria
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7 January 2021
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Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility?
1 reference
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reference URL
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7 January 2021
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Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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Activation of the caspase-3 apoptotic cascade in traumatic spinal cord injury
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Posttreatment with the immunosuppressant cyclosporin A in transient focal ischemia.
1 reference
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7 January 2021
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Cyclosporin ameliorates traumatic brain-injury-induced alterations of hippocampal synaptic plasticity.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Apoptosis in neurodegenerative disorders
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Mechanisms for neuronal cell death and dysfunction in Huntington's disease: pathological cross-talk between the nucleus and the mitochondria?
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Par-4 is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer disease
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.
1 reference
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Crossref
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7 January 2021
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Presenilin mutations and calcium signaling defects in the nervous and immune systems
1 reference
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Chemical preconditioning with 3-nitropropionic acid in hearts: role of mitochondrial K(ATP) channel
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p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism
1 reference
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7 January 2021
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Accomplices to neuronal death
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7 January 2021
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Mitochondrial DNA mutations activate the mitochondrial apoptotic pathway and cause dilated cardiomyopathy.
1 reference
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Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice
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Elucidating the molecular mechanism of the permeability transition pore and its role in reperfusion injury of the heart
1 reference
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse heat shock transcription factor 1 deficiency alters cardiac redox homeostasis and increases mitochondrial oxidative damage
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Calpain and mitochondria in ischemia/reperfusion injury
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
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Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
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Cyclosporin A increases resting mitochondrial membrane potential in SY5Y cells and reverses the depressed mitochondrial membrane potential of Alzheimer's disease cybrids.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporin A attenuates the decrease in tyrosine hydroxylase immunoreactivity in nigrostriatal dopaminergic neurons and in striatal dopamine content in rats with intrastriatal injection of 6-hydroxydopamine.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Modification of brain aging and neurodegenerative disorders by genes, diet, and behavior
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
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Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Caloric restriction restores the cardioprotective effect of preconditioning in the rat heart
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular and mitochondrial changes in glutamate-induced HT4 neuronal cell death
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice.
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
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Neuroprotective abilities of resveratrol and other red wine constituents against nitric oxide-related toxicity in cultured hippocampal neurons
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Folate and homocysteine metabolism in neural plasticity and neurodegenerative disorders
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Protection of cardiac mitochondria by diazoxide and protein kinase C: implications for ischemic preconditioning
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial ATP-dependent potassium channels. Viable candidate effectors of ischemic preconditioning.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential actions of cardioprotective agents on the mitochondrial death pathway
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
Volatile anesthetics mimic cardiac preconditioning by priming the activation of mitochondrial K(ATP) channels via multiple signaling pathways.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
K(ATP) channel gene expression is induced by urocortin and mediates its cardioprotective effect.
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cardioprotective effects of diltiazem infusion in the perioperative period
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
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7 January 2021
based on heuristic
inferred from DOI database lookup
BH4 domain of antiapoptotic Bcl-2 family members closes voltage-dependent anion channel and inhibits apoptotic mitochondrial changes and cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Opening of the mitochondrial permeability transition pore causes depletion of mitochondrial and cytosolic NAD+ and is a causative event in the death of myocytes in postischemic reperfusion of the heart.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sanglifehrin A acts as a potent inhibitor of the mitochondrial permeability transition and reperfusion injury of the heart by binding to cyclophilin-D at a different site from cyclosporin A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporin A protects striatal neurons in vitro and in vivo from 3-nitropropionic acid toxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
K+ channel openers protect hippocampal neurons against oxidative injury and amyloid beta-peptide toxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic treatment with a superoxide dismutase mimetic prevents vascular remodeling and progression of hypertension in salt-loaded stroke-prone spontaneously hypertensive rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protective effects of cyclosporin A from endotoxin-induced myocardial dysfunction and apoptosis in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extending myocardial viability during heart preservation with cyclosporine A.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondria as target for antiischemic drugs
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Metabolic plasticity and the promotion of cardiac protection in ischemia and ischemic preconditioning
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-mediated suppression of glutamate (AMPA) receptor channel activity in hippocampal neurons in response to DNA damage promotes apoptosis and prevents necrosis: implications for neurological side effects of cancer therapy and neurodegenerative
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1471-4914%2803%2900046-7
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1471-4914(03)00046-7
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
PubMed ID
12763524
1 reference
stated in
Europe PubMed Central
PubMed ID
12763524
retrieved
6 August 2017
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