(Q34126426)

31 July 2017

title

The role of osteopontin (OPN/SPP1) haplotypes in the susceptibility to Crohn's disease (English)

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31 July 2017

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12

Darina Czamara

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author name string

Jürgen Glas

1

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31 July 2017

Julia Seiderer

2

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31 July 2017

Corinna Bayrle

3

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31 July 2017

Martin Wetzke

4

1 reference

31 July 2017

Christoph Fries

5

1 reference

31 July 2017

Cornelia Tillack

6

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31 July 2017

Torsten Olszak

7

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31 July 2017

Florian Beigel

8

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31 July 2017

Christian Steib

9

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31 July 2017

Matthias Friedrich

10

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31 July 2017

Julia Diegelmann

11

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31 July 2017

Stephan Brand

13

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31 July 2017

language of work or name

English

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publication date

29 December 2011

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31 July 2017

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31 July 2017

volume

6

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31 July 2017

issue

12

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31 July 2017

page(s)

e29309

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Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

29 December 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Osteopontin, intrinsic tissue regulator of intractable inflammatory diseases

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Identification of an IL-27/osteopontin axis in dendritic cells and its modulation by IFN-gamma limits IL-17-mediated autoimmune inflammation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Genetic variation in osteopontin gene is associated with susceptibility to sarcoidosis in Slovenian population

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

The role of osteopontin in inflammatory processes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

IL-27 is a key regulator of IL-10 and IL-17 production by human CD4+ T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Osteopontin is associated with increased arterial stiffness in rheumatoid arthritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Increased osteopontin expression in dendritic cells amplifies IL-17 production by CD4+ T cells in experimental autoimmune encephalomyelitis and in multiple sclerosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Molecular mechanisms linking wound inflammation and fibrosis: knockdown of osteopontin leads to rapid repair and reduced scarring

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

High plasma osteopontin levels in patients with inflammatory bowel disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Suppression of the bacterial antigen-specific T cell response and the dendritic cell migration to the lymph nodes by osteopontin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

A polymorphic variant inside the osteopontin gene shows association with disease course in oligoarticular juvenile idiopathic arthritis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Osteopontin/Eta-1 upregulated in Crohn's disease regulates the Th1 immune response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Osteopontin gene polymorphisms in Spanish patients with rheumatoid arthritis.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Expression of osteopontin (Eta-1) in Crohn disease of the terminal ileum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Altered wound healing in mice lacking a functional osteopontin gene (spp1).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

28 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin: a versatile regulator of inflammation and biomineralization

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin: a new emerging role in psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Increased osteopontin plasma levels in multiple sclerosis patients correlate with bone-specific markers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Genetic polymorphisms of osteopontin in association with multiple sclerosis in Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Penicillium marneffei causes osteopontin-mediated production of interleukin-12 by peripheral blood mononuclear cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin: a new addition to the constellation of cytokines which drive T helper cell type 1 responses in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin attenuation of dextran sulfate sodium-induced colitis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin as two-sided mediator of intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Association of osteopontin regulatory polymorphisms with systemic sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

The osteopontin gene +1239A/C single nucleotide polymorphism is associated with type 1 diabetes mellitus in the Italian population.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Osteopontin gene variation and cardio/cerebrovascular disease phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Association of alleles at polymorphic sites in the Osteopontin encoding gene in young type 1 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

CEACAM6 gene variants in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Age- and gender-specific modulation of serum osteopontin and interferon-alpha by osteopontin genotype in systemic lupus erythematosus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029309

Differentiation, maturation, and survival of dendritic cells by osteopontin regulation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Role of osteopontin in adhesion, migration, cell survival and bone remodeling

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3248444

Role of osteopontin in synovial Th17 differentiation in rheumatoid arthritis

28 October 2018

1 reference

12 December 2020

Osteopontin expression in ulcerative colitis is distinctly different from that in Crohn's disease and diverticulitis

1 reference

12 December 2020

IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration

1 reference

12 December 2020

Osteopontin gene haplotypes correlate with multiple sclerosis development and progression

1 reference

12 December 2020

Enhanced local production of osteopontin in rheumatoid joints

1 reference

12 December 2020

Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status

1 reference

12 December 2020

Distinct gene expression of osteopontin in patients with ulcerative colitis

1 reference

12 December 2020

Analysis of intracellular osteopontin as a marker of osteoblastic cell differentiation and mesenchymal cell migration

1 reference

12 December 2020

Two single-nucleotide polymorphisms in the 5' and 3' ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus

1 reference

12 December 2020

Osteopontin gene polymorphism in association with systemic lupus erythematosus in Chinese patients

1 reference

12 December 2020

The 795CT polymorphism in osteopontin gene is not associated with multiple sclerosis in a Spanish population

1 reference

12 December 2020

TheATG16L1Gene Variants rs2241879 and rs2241880 (T300A) Are Strongly Associated With Susceptibility to Crohn's Disease in the German Population

1 reference

12 December 2020

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD

1 reference

12 December 2020

Osteopontin, a Protein with Cytokine-like Properties, is Associated with Inflammation in Crohn's Disease

1 reference

12 December 2020

An osteopontin (SPP1) polymorphism is associated with systemic lupus erythematosus

1 reference

12 December 2020

High plasma osteopontin level and its relationship with interleukin-12-mediated type 1 T helper cell response in tuberculosis

1 reference

12 December 2020

Osteopontin gene and clinical severity of multiple sclerosis

1 reference

12 December 2020

Osteopontin augments CD3-mediated interferon-gamma and CD40 ligand expression by T cells, which results in IL-12 production from peripheral blood mononuclear cells

1 reference

12 December 2020

Osteopontin deficiency protects mice from Dextran sodium sulfate-induced colitis

1 reference

12 December 2020

A novel role for interleukin-27 (IL-27) as mediator of intestinal epithelial barrier protection mediated via differential signal transducer and activator of transcription (STAT) protein signaling and induction of antibacterial and anti-inflammatory

1 reference

12 December 2020

Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype

1 reference

12 December 2020

Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis

1 reference

12 December 2020

Circulating levels of osteopontin, osteoprotegerin, total soluble receptor activator of nuclear factor-kappa B ligand, and high-sensitivity C-reactive protein in patients with active rheumatoid arthritis randomized to etanercept alone or in combinat

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0029309

Identifiers

DOI

1 reference

release_kxuz3z5ab5flrhnpxdog5ru6j4

31 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kxuz3z5ab5flrhnpxdog5ru6j4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3248444

1 reference

31 July 2017

1 reference