(Q34139171)

31 July 2017

title

Phosphorylation and degradation of tomosyn-2 de-represses insulin secretion (English)

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31 July 2017

1 reference

1 reference

10

Joshua J Coon

1 reference

31 July 2017

4

Alexander S Hebert

1 reference

31 July 2017

Sushant Bhatnagar

1

1 reference

31 July 2017

Mufaddal S Soni

2

1 reference

31 July 2017

Lindsay S Wrighton

3

1 reference

31 July 2017

Amber S Zhou

5

1 reference

31 July 2017

Pradyut K Paul

6

1 reference

31 July 2017

Trillian Gregg

7

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31 July 2017

Mary E Rabaglia

8

1 reference

31 July 2017

Mark P Keller

9

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31 July 2017

Alan D Attie

11

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31 July 2017

language of work or name

English

0 references

publication date

7 July 2014

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Journal of Biological Chemistry

31 July 2017

published in

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31 July 2017

volume

289

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31 July 2017

issue

36

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31 July 2017

page(s)

25276-25286

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Proteasome dysfunction mediates high glucose-induced apoptosis in rodent beta cells and human islets

31 July 2017

cites work

1 reference

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5 July 2018

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Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation

5 July 2018

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5 July 2018

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Phosphorylation in protein-protein binding: effect on stability and function.

5 July 2018

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Positional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Structural and functional analysis of tomosyn identifies domains important in exocytotic regulation

5 July 2018

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5 July 2018

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Tomosyn inhibits synaptotagmin-1-mediated step of Ca2+-dependent neurotransmitter release through its N-terminal WD40 repeats.

5 July 2018

1 reference

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Insulin enhances glucose-stimulated insulin secretion in healthy humans

5 July 2018

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Fbxo45, a novel ubiquitin ligase, regulates synaptic activity

5 July 2018

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Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis

5 July 2018

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Degradation of cAMP-responsive element-binding protein by the ubiquitin-proteasome pathway contributes to glucotoxicity in beta-cells and human pancreatic islets

5 July 2018

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Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Computational identification of ubiquitylation sites from protein sequences

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release

5 July 2018

1 reference

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The roles of synoviolin in crosstalk between endoplasmic reticulum stress-induced apoptosis and p53 pathway

5 July 2018

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Receptor-mediated regulation of tomosyn-syntaxin 1A interactions in bovine adrenal chromaffin cells

5 July 2018

1 reference

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Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets

5 July 2018

1 reference

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Emerging roles for ubiquitin and protein degradation in neuronal function

5 July 2018

1 reference

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A probability-based approach for high-throughput protein phosphorylation analysis and site localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Tomosyn-1 is involved in a post-docking event required for pancreatic beta-cell exocytosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

SNARE complex regulation by phosphorylation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Essential role of ubiquitin-proteasome system in normal regulation of insulin secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

PKA-catalyzed phosphorylation of tomosyn and its implication in Ca2+-dependent exocytosis of neurotransmitter

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Interpretation of shotgun proteomic data: the protein inference problem

5 July 2018

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Role of ubiquitin-proteasome degradation pathway in biogenesis efficiency of {beta}-cell ATP-sensitive potassium channels

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Open mass spectrometry search algorithm

5 July 2018

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Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Structural basis for the inhibitory role of tomosyn in exocytosis

5 July 2018

1 reference

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5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Tomosyn inhibits priming of large dense-core vesicles in a calcium-dependent manner

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Synoviolin/Hrd1, an E3 ubiquitin ligase, as a novel pathogenic factor for arthropathy

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

SNARE regulators: matchmakers and matchbreakers

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Glucose-stimulated signaling pathways in biphasic insulin secretion

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Ubiquitin and the synapse.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Staring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

The Cell Physiology of Biphasic Insulin Secretion.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Tomosyn: a syntaxin-1-binding protein that forms a novel complex in the neurotransmitter release process

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Ubiquitin C-terminal hydrolase is an immediate-early gene essential for long-term facilitation in Aplysia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Axonal transport of synapsin I-like proteins in rabbit retinal ganglion cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Electrical activity, cAMP concentration, and insulin release in mouse islets of Langerhans

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Axonal transport kinetics and posttranslational modification of synapsin I in mouse retinal ganglion cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4155689

Tomosyn is expressed in beta-cells and negatively regulates insulin exocytosis

5 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.575985

Multiple functional domains are involved in tomosyn regulation of exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.575985

Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.575985

Ubiquitination-dependent mechanisms regulate synaptic growth and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.575985

Modulation of the voltage-gated potassium channel Kv1.5 by the SGK1 protein kinase involves inhibition of channel ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.575985

SIK2 regulates insulin secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.575985

Evidence for a Role of the Ubiquitin-Proteasome Pathway in Pancreatic Islets

21 January 2018

1 reference

12 December 2020

Control of pulsatile 5-HT/insulin secretion from single mouse pancreatic islets by intracellular calcium dynamics

1 reference

12 December 2020

Tomosyn binds t-SNARE proteins via a VAMP-like coiled coil

1 reference

12 December 2020

Tomosyn negatively regulates both synaptic transmitter and neuropeptide release at the C. elegans neuromuscular junction

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.575985

1 reference

31 July 2017

1 reference

31 July 2017

1 reference