(Q34148533)

31 July 2017

title

The key function of a conserved and modified rRNA residue in the ribosomal response to the nascent peptide (English)

1 reference

31 July 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

14 June 2024

4

Krishna Kannan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

14 June 2024

author name string

Nora Vázquez-Laslop

1

1 reference

31 July 2017

Haripriya Ramu

2

1 reference

31 July 2017

Dorota Klepacki

3

1 reference

31 July 2017

Alexander S. Mankin

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

14 June 2024

language of work or name

English

0 references

publication date

30 July 2010

1 reference

full work available at URL

31 July 2017

https://europepmc.org/articles/pmc2944061?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20676057/pdf/?tool=EBI

14 June 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20676057/?tool=EBI

14 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

https://europepmc.org/articles/PMC2944061

14 June 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

https://europepmc.org/articles/PMC2944061?pdf=render

14 June 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

https://doi.org/10.1038/emboj.2010.180

14 June 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20676057

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1038%2Femboj.2010.180

14 June 2024

1 reference

DOI

10.1038/EMBOJ.2010.180

https://api.crossref.org/works/10.1038/EMBOJ.2010.180

14 June 2024

1 reference

31 July 2017

volume

29

1 reference

31 July 2017

issue

18

1 reference

31 July 2017

page(s)

3108-3117

1 reference

The role of the universally conserved A2450-C2063 base pair in the ribosomal peptidyl transferase center.

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Divergent stalling sequences sense and control cellular physiology.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Structural insight into nascent polypeptide chain-mediated translational stalling.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Genetic identification of nascent peptides that induce ribosome stalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

A ribosome-nascent chain sensor of membrane protein biogenesis in Bacillus subtilis.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

The plasticity of a translation arrest motif yields insights into nascent polypeptide recognition inside the ribosome tunnel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Statics of the ribosomal exit tunnel: implications for cotranslational peptide folding, elongation regulation, and antibiotics binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

23S rRNA nucleotides in the peptidyl transferase center are essential for tryptophanase operon induction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Programmed drug-dependent ribosome stalling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Identification of 8-methyladenosine as the modification catalyzed by the radical SAM methyltransferase Cfr that confers antibiotic resistance in bacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Effects on translation pausing of alterations in protein and RNA components of the ribosome exit tunnel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Mutations Outside the Anisomycin-Binding Site Can Make Ribosomes Drug-Resistant

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Translational attenuation and mRNA stabilization as mechanisms of erm(B) induction by erythromycin

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Induction of erm(C) expression by noninducing antibiotics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

The methyltransferase YfgB/RlmN is responsible for modification of adenosine 2503 in 23S rRNA

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Expanding the nucleotide repertoire of the ribosome with post-transcriptional modifications

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Messenger RNA conformations in the ribosomal E site revealed by X-ray crystallography.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Binding site of the bridged macrolides in the Escherichia coli ribosome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

A nascent polypeptide domain that can regulate translation elongation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

The chemistry of protein synthesis and voyage through the ribosomal tunnel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Structural insights into peptide bond formation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Ribosome structure and the mechanism of translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

The ribosomal exit tunnel functions as a discriminating gate

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Regulatory nascent peptides in the ribosomal tunnel

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Structural basis for the interaction of antibiotics with the peptidyl transferase centre in eubacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

A conformational change in the ribosomal peptidyl transferase center upon active/inactive transition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Upstream open reading frames as regulators of mRNA translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

The structural basis of ribosome activity in peptide bond synthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

The complete atomic structure of the large ribosomal subunit at 2.4 A resolution

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

An Escherichia coli strain with all chromosomal rRNA operons inactivated: complete exchange of rRNA genes between bacteria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Insights into erythromycin action from studies of its activity as inducer of resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Posttranscriptional modification of mRNA conformation: mechanism that regulates erythromycin-induced resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Conformational alteration of mRNA structure and the posttranscriptional regulation of erythromycin-induced drug resistance

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Nucleotide sequence of ermA, a macrolide-lincosamide-streptogramin B determinant in Staphylococcus aureus

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Extension inhibition analysis of translation initiation complexes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Ribosomal RNA and translation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Transcriptional attenuation control of ermK, a macrolide-lincosamide-streptogramin B resistance determinant from Bacillus licheniformis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Regulation of the macrolide-lincosamide-streptogramin B resistance gene ermD

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2944061

Features of ribosome-peptidyl-tRNA interactions essential for tryptophan induction of tna operon expression

5 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Instruction of translating ribosome by nascent peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

ErmK leader peptide : amino acid sequence critical for induction by erythromycin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Genetically encoded but nonpolypeptide prolyl-tRNA functions in the A site for SecM-mediated ribosomal stall.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Crystal Structures of the Ribosome in Complex with Release Factors RF1 and RF2 Bound to a Cognate Stop Codon

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Molecular mechanism of drug-dependent ribosome stalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Translation arrest requires two-way communication between a nascent polypeptide and the ribosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

Translational Operator of mRNA on the Ribosome: How Repressor Proteins Exclude Ribosome Binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2010.180

[Some structural aspects of the peptidyltransferase reaction]

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20676057

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2010.180

1 reference

31 July 2017

1 reference

31 July 2017

1 reference