(Q34150236)

English

On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

On the perils of poor editing: regulation of peptide loading by HLA-DQ and H2-A molecules associated with celiac disease and type 1 diabetes (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

type-1 diabetes

0 references

author name string

Robert Busch

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Alessandra De Riva

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Andreas V Hadjinicolaou

3

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Wei Jiang

4

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Tieying Hou

5

1 reference

Europe PubMed Central

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31 July 2017

Elizabeth D Mellins

6

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

publication date

6 July 2012

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Europe PubMed Central

PubMed publication ID

31 July 2017

Expert Reviews in Molecular Medicine

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Europe PubMed Central

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31 July 2017

14

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e15

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Thymic negative selection is functional in NOD mice

1 reference

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5 July 2018

How the TCR balances sensitivity and specificity for the recognition of self and pathogens.

1 reference

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5 July 2018

Towards a systems understanding of MHC class I and MHC class II antigen presentation.

1 reference

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5 July 2018

Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion

1 reference

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5 July 2018

Important lessons derived from animal models of celiac disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

T cell recognition of autoantigens in human type 1 diabetes: clinical perspectives

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

T helper cell differentiation more than just cytokines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Invariant chain processing is independent of cathepsin variation between primary human B cells/dendritic cells and B-lymphoblastoid cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

I-Ag7 is subject to post-translational chaperoning by CLIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The diabetogenic mouse MHC class II molecule I-Ag7 is endowed with a switch that modulates TCR affinity

1 reference

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5 July 2018

Measurement of protein synthesis using heavy water labeling and peptide mass spectrometry: Discrimination between major histocompatibility complex allotypes

1 reference

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5 July 2018

Nomenclature for factors of the HLA system, 2010

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5 July 2018

Targeted regulation of self-peptide presentation prevents type I diabetes in mice without disrupting general immunocompetence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Unique autoreactive T cells recognize insulin peptides generated within the islets of Langerhans in autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Multiple common variants for celiac disease influencing immune gene expression

1 reference

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5 July 2018

Chromogranin A is an autoantigen in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Overcoming self-destruction in the pancreas.

1 reference

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5 July 2018

Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

First signature of islet beta-cell-derived naturally processed peptides selected by diabetogenic class II MHC molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Large-scale characterization of natural ligands explains the unique gluten-binding properties of HLA-DQ2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Posttranslational regulation of I-Ed by affinity for CLIP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

A structural and immunological basis for the role of human leukocyte antigen DQ8 in celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Noncognate interaction with MHC class II molecules is essential for maintenance of T cell metabolism to establish optimal memory CD4 T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Thymic development and peripheral homeostasis of regulatory T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Genes, environment and immunity in the development of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The wide diversity and complexity of peptides bound to class II MHC molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The insulin A-chain epitope recognized by human T cells is posttranslationally modified

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The relationship between immunodominance, DM editing, and the kinetic stability of MHC class II:peptide complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The lysosomal cysteine proteases in MHC class II antigen presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Interaction of HLA-DR with an acidic face of HLA-DM disrupts sequence-dependent interactions with peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Nonobese diabetic (NOD) mouse dendritic cells stimulate insulin secretion by prediabetic islets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Impaired processing and presentation by MHC class II proteins in human diabetic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Projection of an immunological self shadow within the thymus by the aire protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Structural basis for gluten intolerance in celiac sprue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Restricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Genetic control of MHC class II expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Specificity of tissue transglutaminase explains cereal toxicity in celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Electrostatics of nanosystems: application to microtubules and the ribosome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Islet endocrine-cell behavior from birth onward in mice with the nonobese diabetic genetic background

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Nonobese diabetic mice display elevated levels of class II-associated invariant chain peptide associated with I-Ag7 on the cell surface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

CLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The down-regulation of HLA-DM gene expression in rheumatoid arthritis is not related to their promoter polymorphism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The I-Ag7 MHC class II molecule linked to murine diabetes is a promiscuous peptide binder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The MHC class II molecule I-Ag7 exists in alternate conformations that are peptide dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Accessory molecules for MHC class II peptide loading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Extracellular antigen processing and presentation by immature dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

pH-dependent peptide binding properties of the type I diabetes-associated I-Ag7 molecule: rapid release of CLIP at an endosomal pH.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Analysis of the role of variation of major histocompatibility complex class II expression on nonobese diabetic (NOD) peripheral T cell response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Exceptional stability of the HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC molecule associated with protection from insulin-dependent diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Crystal structure of mouse H2-M

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Secondary structure composition and pH-dependent conformational changes of soluble recombinant HLA-DM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The inability of the nonobese diabetic class II molecule to form stable peptide complexes does not reflect a failure to interact productively with DM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA-DO is a negative modulator of HLA-DM-mediated MHC class II peptide loading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Negative regulation by HLA-DO of MHC class II-restricted antigen processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

In the absence of the invariant chain, HLA-DR molecules display a distinct array of peptides which is influenced by the presence or absence of HLA-DM

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA-DM interactions with intermediates in HLA-DR maturation and a role for HLA-DM in stabilizing empty HLA-DR molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Genetics of coeliac disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

B lymphocytes are essential for the initiation of T cell-mediated autoimmune diabetes: analysis of a new "speed congenic" stock of NOD.Ig mu null mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Invariant chain and DM edit self-peptide presentation by major histocompatibility complex (MHC) class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Developing and shedding inhibitions: how MHC class II molecules reach maturity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Isolation of nonobese diabetic mouse T-cells that recognize novel autoantigens involved in the early events of diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

A genome-wide search for human type 1 diabetes susceptibility genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Assembly, transport, and function of MHC class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

T cells from the peripheral blood of coeliac disease patients recognize gluten antigens when presented by HLA-DR, -DQ, or -DP molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

MHC ligands and peptide motifs: first listing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Binding of major histocompatibility complex class II to the invariant chain-derived peptide, CLIP, is regulated by allelic polymorphism in class II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Aspartate at position 57 of nonobese diabetic I-Ag7 beta-chain diminishes the spontaneous incidence of insulin-dependent diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

An ion pair in class II major histocompatibility complex heterodimers critical for surface expression and peptide presentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Structural features of the invariant chain fragment CLIP controlling rapid release from HLA-DR molecules and inhibition of peptide binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA-DM induces clip dissociation from MHC class II αβ dimers and facilitates peptide loading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Mediation by HLA-DM of dissociation of peptides from HLA-DR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The structure of an intermediate in class II MHC maturation: CLIP bound to HLA-DR3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Breeding of a non-obese, diabetic strain of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Autoimmunity and HLA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Absence of insulitis and overt diabetes in athymic nude mice with NOD genetic background.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

HLA-DQ beta gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

5 July 2018

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Measurement of cell proliferation by heavy water labeling.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Measurement of protein turnover rates by heavy water labeling of nonessential amino acids.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Measurement of proliferation and disappearance of regulatory T cells in human studies using deuterium-labeled glucose.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Both central and peripheral tolerance mechanisms play roles in diabetes prevention in NOD-E transgenic mice.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

An insertion mutant in DQA1*0501 restores susceptibility to HLA-DM: implications for disease associations.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Marginal-zone B-cells of nonobese diabetic mice expand with diabetes onset, invade the pancreatic lymph nodes, and present autoantigen to diabetogenic T-cells

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Intestinal digestive resistance of immunodominant gliadin peptides

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Gluten-dependent enteropathy and atypical human leukocyte antigen alleles

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease-associated HLA-DQ2 molecule.

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Elevated Lymphocyte Expression of CLIP Is Associated with Type 1 Diabetes and May Be a Useful Marker of Autoimmune Susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

28 October 2018

Molecular characterization of the diabetes-associated mouse MHC class II protein, I-Ag7

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4157902

28 October 2018

Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Peptide binding inhibits protein aggregation of invariant-chain free class II dimers and promotes surface expression of occupied molecules

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Prevention of insulin-dependent diabetes mellitus in non-obese diabetic mice by transgenes encoding modified I-A β-chain or normal I-E α-chain

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

21 January 2018

Dissecting MHC class II export, B cell maturation, and DM stability defects in invariant chain mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Susceptibility to develop celiac disease is primarily associated with HLA-DQ alleles

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated T lymphocytes in the celiac lesion: non-proliferative activation (CD25) of CD4+ alpha/beta cells in the lamina propria but proliferation (Ki-67) of alpha/beta and gamma/delta cells in the epithelium

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of Autoimmune Diabetes from Diabetic NOD Mice to NOD Athymic Nude Mice: The Roles of T Cell Subsets in the Pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An autoantigenic T cell epitope forms unstable complexes with class II MHC: a novel route for escape from tolerance induction

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Self peptides isolated from MHC glycoproteins of non-obese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of invariant chain protects nonobese diabetic mice against type 1 diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glutenin is involved in the gluten-driven mucosal T cell response

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The arthritogenic T cell receptor and its ligand in a model of spontaneous arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The association of HLA-DM genes with rheumatoid arthritis in Eastern France

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A defect in bone marrow derived dendritic cell maturation in the nonobesediabetic mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of lysozyme peptides bound to class II MHC molecules indicates very large differences in levels of presentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DM loss in k haplotype mice reveals isotype-specific chaperone requirements

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Editing of an immunodominant epitope of glutamate decarboxylase by HLA-DM

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MHC-linked susceptibility to type 1 diabetes: a structural perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential contributions of APC subsets to T cell activation in nonobese diabetic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High frequency of low-risk human leukocyte antigen class II genotypes in latent celiac disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding type 1 diabetes through genetics: advances and prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The class II MHC I-Ag7 molecules from non-obese diabetic mice are poor peptide binders

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-dependent diabetes mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dermatitis herpetiformis and celiac disease are both primarily associated with the HLA-DQ (α1*0501, (β1*02) or the HLA-DQ (α1*03, (β1*0302) heterodimers

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HLA-DM stabilizes empty HLA-DR molecules in a chaperone-like fashion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22805744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls

1 reference

https://api.crossref.org/works/10.1017%2FERM.2012.9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1017/ERM.2012.9

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

0 references

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