(Q34154104)

31 July 2017

Effects of antalarmin, a CRF type 1 receptor antagonist, on anxiety-like behavior and motor activation in the rat. (English)

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31 July 2017

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4

George F Koob

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31 July 2017

Eric P Zorrilla

1

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31 July 2017

Glenn R Valdez

series ordinal

2

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31 July 2017

Joachim Nozulak

series ordinal

3

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31 July 2017

Athina Markou

series ordinal

5

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31 July 2017

language of work or name

English

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publication date

1 October 2002

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31 July 2017

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31 July 2017

952

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31 July 2017

188-199

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31 July 2017

2

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Handling history of rats modifies behavioural effects of drugs in the elevated plus-maze test of anxiety.

31 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing hormone and animal models of anxiety: gene-environment interactions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Reduction of stress-induced behavior by antagonism of corticotropin-releasing hormone 2 (CRH2) receptors in lateral septum or CRH1 receptors in amygdala.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

CRF antagonist reverses the "anxiogenic" response to ethanol withdrawal in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The CRF1 receptor mediates the excitatory actions of corticotropin releasing factor (CRF) in the developing rat brain: in vivo evidence using a novel, selective, non-peptide CRF receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin releasing factor (CRF) binding protein: a novel regulator of CRF and related peptides

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Previous maze experience required to increase open arms avoidance in rats submitted to the elevated plus-maze model of anxiety.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Role of endogenous corticotropin-releasing factor in mediation of neuroendocrine and behavioral responses to cholecystokinin octapeptide sulfate ester in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Chronic effects of a nonpeptide corticotropin-releasing hormone type I receptor antagonist on pituitary-adrenal function, body weight, and metabolic regulation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Antalarmin blockade of corticotropin releasing hormone-induced hypertension in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin releasing factor (CRF) receptor antagonist blocks activating and 'anxiogenic' actions of CRF in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Design and synthesis of a series of non-peptide high-affinity human corticotropin-releasing factor1 receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Synthesis and oral efficacy of a 4-(butylethylamino)pyrrolo[2,3-d]pyrimidine: a centrally active corticotropin-releasing factor1 receptor antagonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Central administration of a CRF antagonist blocks the development of stress-induced behavioral sensitization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Low doses of corticotropin-releasing factor potentiate amphetamine-induced stereotyped behavior

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Reduced anxiety-like and cognitive performance in mice lacking the corticotropin-releasing factor receptor 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Dissociation of locomotor activation and suppression of food intake induced by CRF in CRFR1-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Ethopharmacological analysis of rat behavior on the elevated plus-maze.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor receptors: physiology, pharmacology, biochemistry and role in central nervous system and immune disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Behavioral responses to stress are intact in CRF-deficient mice.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The influence of open arm ledges and maze experience in the elevated plus-maze.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Factor analysis shows that female rat behaviour is characterized primarily by activity, male rats are driven by sex and anxiety.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Trial 2 in the elevated plus-maze: a different form of fear?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin releasing factor (CRF) receptor modulators: progress and opportunities for new therapeutic agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Effects of the CRH receptor antagonist CP-154,526 on intravenous cocaine self-administration in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Characterization of the behavioral profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents. Comparison with diazepam and buspirone.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

4-(2-Chloro-4-methoxy-5-methylphenyl)-N-[(1S)-2-cyclopropyl-1-(3-fluoro-4-methylphenyl)ethyl]5-methyl-N-(2-propynyl)-1, 3-thiazol-2-amine hydrochloride (SSR125543A), a potent and selective corticotrophin-releasing factor(1) receptor antagonist. II.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Oral administration of a corticotropin-releasing hormone receptor antagonist significantly attenuates behavioral, neuroendocrine, and autonomic responses to stress in primates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The effects of CRA 1000, a non-peptide antagonist of corticotropin-releasing factor receptor type 1, on adaptive behaviour in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

4-(1,3-Dimethoxyprop-2-ylamino)-2,7-dimethyl-8-(2, 4-dichlorophenyl)pyrazolo[1,5-a]-1,3,5-triazine: a potent, orally bioavailable CRF(1) receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor CRF1, but not CRF2, receptors mediate anxiogenic-like behavior

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Anti-stress action of a corticotropin-releasing factor antagonist on behavioral reactivity to stressors of varying type and intensity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor antagonist reduces emotionality in socially defeated rats via direct neurotropic action.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Suppression of conditioned fear by administration of CRF receptor antagonist CP-154,526.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

A review of the validity and variability of the elevated plus-maze as an animal model of anxiety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The rationale for corticotropin-releasing hormone receptor (CRH-R) antagonists to treat depression and anxiety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor receptor type 1 mediates emotional stress-induced inhibition of food intake and behavioral changes in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

CRHR1 Receptor binding and lipophilicity of pyrrolopyrimidines, potential nonpeptide corticotropin-releasing hormone type 1 receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Differential effects of two corticotropin-releasing factor antagonists on conditioned defeat in male Syrian hamsters (Mesocricetus auratus)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Alpha-helical CRF(9-41) prevents anxiogenic-like effect of NPY Y1 receptor antagonist BIBP3226 in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The anxiolytic effect of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Effects of the CRF(1) receptor antagonist, CP 154,526, in the separation-induced vocalization anxiolytic test in rat pups.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Brain pharmacokinetics of a nonpeptidic corticotropin-releasing factor receptor antagonist

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Involvement of corticotropin-releasing factor in the retrieval process of fear-conditioned ultrasonic vocalization in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

A role for corticotropin releasing factor and urocortin in behavioral responses to stressors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Effects of Alpha-Flupenthixol and Naloxone on CRF-Induced Locomotor Activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Differential behavioural effects of chronic infusion of CRH 1 and CRH 2 receptor antisense oligonucleotides into the rat brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Chronic infusion of a CRH1 receptor antisense oligodeoxynucleotide into the central nucleus of the amygdala reduced anxiety-related behavior in socially defeated rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

A non peptidic corticotropin releasing factor receptor antagonist attenuates fever and exhibits anxiolytic-like activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Role of CRF receptor 1 in central CRF-induced stimulation of colonic propulsion in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Involvement of hypothalamic corticotropin-releasing factor neurons in behavioral responses to novelty in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Anxiolytic properties of the selective, non-peptidergic CRF(1) antagonists, CP154,526 and DMP695: a comparison to other classes of anxiolytic agent

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Urocortin, a novel neuropeptide with anxiogenic-like properties

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Design, synthesis and structure-affinity relationships of 4-methylidenepiperidine and 4-aryl-1,2,3,6-tetrahydropyridine derivatives as corticotropin-releasing factor1 receptor antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The role of the CRH type 1 receptor in autonomic responses to corticotropin- releasing hormone in the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Urocortin in the ventromedial hypothalamic nucleus acts as an inhibitor of feeding behavior in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor antagonists in affective disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: a novel test of anxiety in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing hormone receptor type 1-deficiency enhances hippocampal serotonergic neurotransmission: an in vivo microdialysis study in mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Intraclass correlations: uses in assessing rater reliability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor is a potent inhibitor of sexual receptivity in the female rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing hormone receptor (type I) antisense targeting reduces anxiety.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Appetite-suppressing effects of urocortin, a CRF-related neuropeptide.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Behavioral effects of central administration of the novel CRF antagonist astressin in rats.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Overproduction of corticotropin-releasing factor in transgenic mice: a genetic model of anxiogenic behavior.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Separate neural substrates of the locomotor-activating properties of amphetamine, heroin, caffeine and corticotropin releasing factor (CRF) in the rat.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

The neural substrates for the motor-activating properties of psychostimulants: a review of recent findings.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Behavioral activation by CRF: evidence for the involvement of the ventral forebrain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Human urocortin II: mild locomotor suppressive and delayed anxiolytic-like effects of a novel corticotropin-releasing factor related peptide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Ethological confirmatory factor analysis of anxiety-like behaviour in the murine elevated plus-maze.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

In vivo and in vitro characterization of antalarmin, a nonpeptide corticotropin-releasing hormone (CRH) receptor antagonist: suppression of pituitary ACTH release and peripheral inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2802%2903189-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-8993(02)03189-X

1 reference

31 July 2017

1 reference