(Q34164894)

31 July 2017

Cortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1. (English)

1 reference

31 July 2017

1 reference

7

Paul M Stewart

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Alexander J. Lawson

object named as

Alexander J Lawson

1

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Wiebke Arlt

object named as

Wiebke Arlt

6

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author name string

Elizabeth A Walker

2

1 reference

31 July 2017

Gareth G Lavery

3

1 reference

31 July 2017

Iwona J Bujalska

4

1 reference

31 July 2017

Beverly Hughes

5

1 reference

31 July 2017

Jonathan P Ride

8

1 reference

31 July 2017

language of work or name

English

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publication date

15 February 2011

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Proceedings of the National Academy of Sciences of the United States of America

31 July 2017

1 reference

31 July 2017

108

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31 July 2017

10

1 reference

31 July 2017

4111-4116

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Mutations of key hydrophobic surface residues of 11β-hydroxysteroid dehydrogenase type 1 increase solubility and monodispersity in a bacterial expression system

31 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Hexose 6-phosphate dehydrogenase (H6PD) and corticosteroid metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Mechanisms of disease: Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

UCSF Chimera--a visualization system for exploratory research and analysis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Close-range electrostatic interactions in proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Critical residues for structure and catalysis in short-chain dehydrogenases/reductases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Functional expression, characterization, and purification of the catalytic domain of human 11-beta -hydroxysteroid dehydrogenase type 1.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Targeting proteins to the lumen of endoplasmic reticulum using N-terminal domains of 11beta-hydroxysteroid dehydrogenase and the 50-kDa esterase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Does central obesity reflect "Cushing's disease of the omentum"?

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Complex salt bridges in proteins: statistical analysis of structure and function

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Daily cortisol production rate in man determined by stable isotope dilution/mass spectrometry

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

11Beta-hydroxysteroid dehydrogenase type 1: purification from human liver and characterization as carbonyl reductase of xenobiotics

5 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

High-level production and optimization of monodispersity of 11beta-hydroxysteroid dehydrogenase type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

The crystal structure of guinea pig 11beta-hydroxysteroid dehydrogenase type 1 provides a model for enzyme-lipid bilayer interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Crystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Conformational flexibility in crystal structures of human 11beta-hydroxysteroid dehydrogenase type I provide insights into glucocorticoid interconversion and enzyme regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Hexose-6-phosphate dehydrogenase knock-out mice lack 11 beta-hydroxysteroid dehydrogenase type 1-mediated glucocorticoid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Hexose-6-phosphate dehydrogenase confers oxo-reductase activity upon 11 beta-hydroxysteroid dehydrogenase type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Protein stability and surface electrostatics: a charged relationship.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Electrostatic enhancement of diffusion-controlled protein-protein association: comparison of theory and experiment on barnase and barstar.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Interactions across the interface contribute the stability of homodimeric 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Thermostability of salt bridges versus hydrophobic interactions in proteins probed by statistical potentials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Defects in the HSD11 gene encoding 11 beta-hydroxysteroid dehydrogenase are not found in patients with apparent mineralocorticoid excess or 11-oxoreductase deficiency.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3054023

Tyr-179 and Lys-183 are essential for enzymatic activity of 11β-hydroxysteroid dehydrogenase

28 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Protein-protein association: investigation of factors influencing association rates by Brownian dynamics simulations

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Salt Bridges Stabilize the Folded Structure of Barnase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1014934108

Mass spectrometry in the diagnosis of steroid-related disorders and in hypertension research

21 January 2018

1 reference

12 December 2020

Apparent cortisone reductase deficiency: a unique form of hypercortisolism

1 reference

12 December 2020

Failure of cortisone acetate treatment in congenital adrenal hyperplasia because of defective 11beta-hydroxysteroid dehydrogenase reductase activity

1 reference

12 December 2020

Apparent cortisone reductase deficiency: a functional defect in 11beta-hydroxysteroid dehydrogenase type 1

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1014934108

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference