(Q34175578)

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Sortilin: an unusual suspect in cholesterol metabolism: from GWAS identification to in vivo biochemical analyses, sortilin has been identified as a novel mediator of human lipoprotein metabolism

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

Sortilin: an unusual suspect in cholesterol metabolism: from GWAS identification to in vivo biochemical analyses, sortilin has been identified as a novel mediator of human lipoprotein metabolism (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

genome-wide association study

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1 reference

based on heuristic

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Robert A. Hegele

3

object named as

Robert A Hegele

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author name string

Joseph B Dubé

1

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Europe PubMed Central

PubMed publication ID

31 July 2017

Christopher T Johansen

2

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Europe PubMed Central

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31 July 2017

language of work or name

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publication date

4 April 2011

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Europe PubMed Central

PubMed publication ID

31 July 2017

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Europe PubMed Central

PubMed publication ID

31 July 2017

33

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Europe PubMed Central

PubMed publication ID

31 July 2017

6

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Europe PubMed Central

PubMed publication ID

31 July 2017

430-437

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Europe PubMed Central

PubMed publication ID

31 July 2017

describes a project that uses

genome-wide association study

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based on heuristic

inferred from title

Atherosclerosis

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Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials

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Translating molecular discoveries into new therapies for atherosclerosis

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Monogenic hypercholesterolemia: new insights in pathogenesis and treatment

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Plasma lipoproteins: genetic influences and clinical implications

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Complement factor H polymorphism in age-related macular degeneration

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High-resolution whole-genome association study of Parkinson disease.

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Genetic mapping in human disease

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Genomewide association analysis of coronary artery disease

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https://api.crossref.org/works/10.1002%2FBIES.201100003

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Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

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https://api.crossref.org/works/10.1002%2FBIES.201100003

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The novel genetic variant predisposing to coronary artery disease in the region of the PSRC1 and CELSR2 genes on chromosome 1 associates with serum cholesterol

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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Newly identified loci that influence lipid concentrations and risk of coronary artery disease

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https://api.crossref.org/works/10.1002%2FBIES.201100003

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LDL-cholesterol concentrations: a genome-wide association study

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https://api.crossref.org/works/10.1002%2FBIES.201100003

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Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia

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Large scale association analysis of novel genetic loci for coronary artery disease

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Common variants at 30 loci contribute to polygenic dyslipidemia

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Replication of genetic associations with plasma lipoprotein traits in a multiethnic sample

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Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip

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Biological, clinical and population relevance of 95 loci for blood lipids

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

The carboxy-terminal domain of the receptor-associated protein binds to the Vps10p domain of sortilin

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

The Vps10p-domain receptor family.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

The luminal Vps10p domain of sortilin plays the predominant role in targeting to insulin-responsive Glut4-containing vesicles

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Sortilin is essential for proNGF-induced neuronal cell death

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Endocytosis of apolipoprotein A-V by members of the low density lipoprotein receptor and the VPS10p domain receptor families

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

21 January 2018

Mapping the genetic architecture of gene expression in human liver

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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The inactivation of the sortilin gene leads to a partial disruption of prosaposin trafficking to the lysosomes

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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Roles for the pro-neurotrophin receptor sortilin in neuronal development, aging and brain injury

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Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin.

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https://api.crossref.org/works/10.1002%2FBIES.201100003

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Small animal models of cardiovascular disease: tools for the study of the roles of metabolic syndrome, dyslipidemia, and atherosclerosis

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https://api.crossref.org/works/10.1002%2FBIES.201100003

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Short-term adaptation of postprandial lipoprotein secretion and intestinal gene expression to a high-fat diet.

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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Integrated hepatic transcriptome and proteome analysis of mice with high-fat diet-induced nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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Sortilin is upregulated during osteoblastic differentiation of mesenchymal stem cells and promotes extracellular matrix mineralization

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201100003

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Gene expression profiling of human mesenchymal stem cells derived from bone marrow during expansion and osteoblast differentiation

1 reference

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21 January 2018

Identifiers

10.1002/BIES.201100003

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

ResearchGate publication ID

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