(Q34180376)

31 July 2017

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title

Molecular basis of lithium action: integration of lithium-responsive signaling and gene expression networks (English)

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31 July 2017

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R H Lenox

1

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31 July 2017

Le Wang

series ordinal

2

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31 July 2017

language of work or name

English

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publication date

1 February 2003

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31 July 2017

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31 July 2017

8

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31 July 2017

2

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31 July 2017

135-144

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https://scigraph.springernature.com/pub.10.1038/sj.mp.4001306

31 July 2017

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cites work

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Transduction of psychosocial stress into the neurobiology of recurrent affective disorder

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Risk of Recurrence Following Discontinuation of Lithium Treatment in Bipolar Disorder

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Lithium maintenance treatment of depression and mania in bipolar I and bipolar II disorders

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Signaling: cellular insights into the pathophysiology of bipolar disorder

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Initiation and adaptation: a paradigm for understanding psychotropic drug action

21 January 2018

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Definition of a metal-dependent/Li(+)-inhibited phosphomonoesterase protein family based upon a conserved three-dimensional core structure

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Molecular targets of lithium action

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Inositol phosphate biochemistry

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Ziskind-Somerfeld Research Award. Protein kinase C signaling in the brain: molecular transduction of mood stabilization in the treatment of manic-depressive illness

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium and the phosphoinositide cycle: an example of uncompetitive inhibition and its pharmacological consequences

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Reduced inositol polyphosphate accumulation and inositol supply induced by lithium in stimulated cerebral cortex slices

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Evidence that a proconvulsant action of lithium is mediated by inhibition of myo-inositol phosphatase in mouse brain

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium and myo-inositol homeostasis

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Long-term action of lithium: a role for transcriptional and posttranscriptional factors regulated by protein kinase C.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Modulation of protein kinase C isozymes and substrates by lithium: the role of myo-inositol

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

AP-1 and NF-kappaB stimulated by carbachol in human neuroblastoma SH-SY5Y cells are differentially sensitive to inhibition by lithium.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Increased membrane-associated protein kinase C activity and translocation in blood platelets from bipolar affective disorder patients

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Increased association of brain protein kinase C with the receptor for activated C kinase-1 (RACK1) in bipolar affective disorder

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Interaction among GSK-3, GBP, axin, and APC in Xenopus axis specification

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Identification of c-MYC as a target of the APC pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Activation of the Wnt signaling pathway: a molecular mechanism for lithium action.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A molecular mechanism for the effect of lithium on development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

The mood stabilizer valproic acid activates mitogen-activated protein kinases and promotes neurite growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Valproate regulates GSK-3-mediated axonal remodeling and synapsin I clustering in developing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Glycogen synthase kinase 3: an emerging therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Wnt signaling and heterotrimeric G-proteins: strange bedfellows or a classic romance?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Munc18-1 promotes large dense-core vesicle docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Lithium ions enhance cysteine string protein gene expression in vivo and in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

The DnaJ-like cysteine string protein and exocytotic neurotransmitter release

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Evoked transmitter release at neuromuscular junctions in wild type and cysteine string protein null mutant larvae of Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

The MARCKS brothers: a family of protein kinase C substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

GAP43, MARCKS, and CAP23 modulate PI(4,5)P(2) at plasmalemmal rafts, and regulate cell cortex actin dynamics through a common mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Myristoylated alanine-rich C kinase substrate (MARCKS) produces reversible inhibition of phospholipase C by sequestering phosphatidylinositol 4,5-bisphosphate in lateral domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Overexpression of myristoylated alanine-rich C-kinase substrate enhances activation of phospholipase D by protein kinase C in SK-N-MC human neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

MARCKS protein is a key molecule regulating mucin secretion by human airway epithelial cells in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A role for MARCKS, the alpha isozyme of protein kinase C and myosin I in zymosan phagocytosis by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

MARCKS deficiency in mice leads to abnormal brain development and perinatal death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Nonmyristoylated MARCKS complements some but not all of the developmental defects associated with MARCKS deficiency in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Phosphorylation and associated translocation of the 87-kDa protein, a major protein kinase C substrate, in isolated nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Regulation of angiotensin II-induced neuromodulation by MARCKS in brain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Effect of reduced myristoylated alanine-rich C kinase substrate expression on hippocampal mossy fiber development and spatial learning in mutant mice: transgenic rescue and interactions with gene background

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Transcriptional down-regulation of MARCKS gene expression in immortalized hippocampal cells by lithium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A common mechanism of action for three mood-stabilizing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Transcriptional regulation of mouse MARCKS promoter in immortalized hippocampal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

The biology of left-handed Z-DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Analysis of gene expression with cDNA microarrays in rat brain after 7 and 42 days of oral lithium administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Linking the genes: inferring quantitative gene networks from microarray data

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Genome-wide location and function of DNA binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A provisional regulatory gene network for specification of endomesoderm in the sea urchin embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

A regulatory gene network that directs micromere specification in the sea urchin embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

Outcome after rapid vs gradual discontinuation of lithium treatment in bipolar disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Nuclear lipid signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Lithium reduces the accumulation of inositol polyphosphate second messengers following cholinergic stimulation of cerebral cortex slices

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Chronic lithium-induced down-regulation of MARCKS in immortalized hippocampal cells: potentiation by muscarinic receptor activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Concurrent measures of protein kinase C and phosphoinositides in lithium-treated bipolar patients and healthy individuals: a preliminary study

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

A preliminary investigation of a protein kinase C inhibitor in the treatment of acute mania

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Increase in the pool size of releasable synaptic vesicles by the activation of protein kinase C in goldfish retinal bipolar cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Activation of protein kinase C-alpha and translocation of the myristoylated alanine-rich C-kinase substrate correlate with phorbol ester-enhanced noradrenaline release from SH-SY5Y human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Localization of the MARCKS (87 kDa) protein, a major specific substrate for protein kinase C, in rat brain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Obligatory role of protein kinase Cbeta and MARCKS in vesicular trafficking in living neurons

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Phorbol ester- and retinoic acid-induced regulation of the protein kinase C substrate MARCKS in immortalized hippocampal cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.MP.4001306

7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001306

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference