(Q34184384)

31 July 2017

title

p53 regulates cell cycle and microRNAs to promote differentiation of human embryonic stem cells (English)

1 reference

human embryonic stem cell

31 July 2017

1 reference

1 reference

Kendra Allton

2

0 references

Abhinav K Jain

object named as

Abhinav K Jain

1

0 references

Michelle Craig Barton

object named as

Michelle Craig Barton

8

0 references

Michael Kyba

object named as

Michael Kyba

7

0 references

author name string

Michelina Iacovino

3

1 reference

31 July 2017

Elisabeth Mahen

4

1 reference

31 July 2017

Robert J Milczarek

5

1 reference

31 July 2017

Thomas P Zwaka

6

1 reference

31 July 2017

language of work or name

English

0 references

publication date

28 February 2012

1 reference

31 July 2017

1 reference

31 July 2017

volume

10

1 reference

31 July 2017

issue

2

1 reference

31 July 2017

page(s)

e1001268

1 reference

Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

28 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states

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miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells

5 July 2018

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Opposing microRNA families regulate self-renewal in mouse embryonic stem cells

5 July 2018

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Direct cell reprogramming is a stochastic process amenable to acceleration

5 July 2018

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5 July 2018

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

5 July 2018

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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells

5 July 2018

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

5 July 2018

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The Ink4/Arf locus is a barrier for iPS cell reprogramming

5 July 2018

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Linking the p53 tumour suppressor pathway to somatic cell reprogramming

5 July 2018

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Tumour suppression by p53: the importance of apoptosis and cellular senescence

5 July 2018

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Trim24 targets endogenous p53 for degradation

5 July 2018

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Blinded by the Light: The Growing Complexity of p53

5 July 2018

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MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

5 July 2018

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p53 represses c-Myc through induction of the tumor suppressor miR-145

5 July 2018

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p53 regulates hematopoietic stem cell quiescence.

5 July 2018

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An isogenetic myoblast expression screen identifies DUX4-mediated FSHD-associated molecular pathologies

5 July 2018

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MicroRNAs in embryonic stem cells

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

miR-34a repression of SIRT1 regulates apoptosis

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

A complex barcode underlies the heterogeneous response of p53 to stress

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells.

5 July 2018

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Downregulation of CCND1 and CDK6 by miR-34a induces cell cycle arrest

5 July 2018

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Comprehensive microRNA profiling reveals a unique human embryonic stem cell signature dominated by a single seed sequence

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

An extended transcriptional network for pluripotency of embryonic stem cells

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Stem cells, the molecular circuitry of pluripotency and nuclear reprogramming

5 July 2018

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Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p53 regulates maternal reproduction through LIF

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Induced pluripotent stem cell lines derived from human somatic cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

MicroRNA expression pattern of undifferentiated and differentiated human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p53 enters the microRNA world

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Cell cycle control of embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Self-renewal of human embryonic stem cells is supported by a shortened G1 cell cycle phase

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Dissecting self-renewal in stem cells with RNA interference

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Control of developmental regulators by Polycomb in human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p53 ubiquitination: Mdm2 and beyond

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

miRBase: microRNA sequences, targets and gene nomenclature

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Core transcriptional regulatory circuitry in human embryonic stem cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p63 deficiency activates a program of cellular senescence and leads to accelerated aging

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Combinatorial microRNA target predictions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p53 induces differentiation of mouse embryonic stem cells by suppressing Nanog expression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Curcumin, a novel p300/CREB-binding protein-specific inhibitor of acetyltransferase, represses the acetylation of histone/nonhistone proteins and histone acetyltransferase-dependent chromatin transcription

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Second-generation tetracycline-regulatable promoter: repositioned tet operator elements optimize transactivator synergy while shorter minimal promoter offers tight basal leakiness

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

MicroRNAs: genomics, biogenesis, mechanism, and function

5 July 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

5 July 2018

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

Prediction of mammalian microRNA targets

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Pluripotent cell division cycles are driven by ectopic Cdk2, cyclin A/E and E2F activities

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Germline transmission and tissue-specific expression of transgenes delivered by lentiviral vectors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Regulation of the G2/M transition by p53.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Myc represses the p21(WAF1/CIP1) promoter and interacts with Sp1/Sp3.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

High metastatic potential in mice inheriting a targeted p53 missense mutation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Regulation of p53 stability

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Human embryonic stem cells.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p63 is a p53 homologue required for limb and epidermal morphogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Embryonic stem cell lines derived from human blastocysts

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

WAF1, a potential mediator of p53 tumor suppression

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells

5 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

Acetylation of p53 inhibits its ubiquitination by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

p53 suppresses the self-renewal of adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

Modeling disease in human ESCs using an efficient BAC-based homologous recombination system

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

High-frequency developmental abnormalities in p53-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PBIO.1001268

Clonal analysis of differentiating embryonic stem cells reveals a hematopoietic progenitor with primitive erythroid and adult lymphoid-myeloid potential

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289600

Contrasting patterns of retinoblastoma protein expression in mouse embryonic stem cells and embryonic fibroblasts

28 October 2018

1 reference

12 December 2020

A subset of p53-deficient embryos exhibit exencephaly

1 reference

12 December 2020

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

1 reference

12 December 2020

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

1 reference

12 December 2020

Regulation of apoptosis and differentiation by p53 in human embryonic stem cells

1 reference

12 December 2020

Expression profiles of miRNAs in human embryonic stem cells during hepatocyte differentiation

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.1001268

Identifiers

DOI

1 reference

31 July 2017

1 reference

31 July 2017

1 reference