(Q34186057)

31 July 2017

title

Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice (English)

1 reference

31 July 2017

Hong-Cheng Wang

1

1 reference

31 July 2017

Vincent Peng

series ordinal

2

1 reference

31 July 2017

Ying Zhao

series ordinal

3

1 reference

31 July 2017

Xiao-Hong Sun

series ordinal

4

1 reference

31 July 2017

language of work or name

English

0 references

publication date

29 February 2012

1 reference

31 July 2017

1 reference

31 July 2017

volume

7

1 reference

31 July 2017

issue

2

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31 July 2017

page(s)

e32944

1 reference

Creative Commons Attribution 4.0 International

31 July 2017

copyright license

start time

29 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.

5 July 2018

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The favorable effect of activating NOTCH1 receptor mutations on long-term outcome in T-ALL patients treated on the ALL-BFM 2000 protocol can be separated from FBXW7 loss of function

5 July 2018

1 reference

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Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.

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Hes1 potentiates T cell lymphomagenesis by up-regulating a subset of notch target genes

5 July 2018

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5 July 2018

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Id1 attenuates Notch signaling and impairs T-cell commitment by elevating Deltex1 expression

5 July 2018

1 reference

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Inhibition of NOTCH signaling by gamma secretase inhibitor engages the RB pathway and elicits cell cycle exit in T-cell acute lymphoblastic leukemia cells.

5 July 2018

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Apoptosis in T cell acute lymphoblastic leukemia cells after cell cycle arrest induced by pharmacological inhibition of notch signaling.

5 July 2018

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Id1 potentiates NF-kappaB activation upon T cell receptor signaling

5 July 2018

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5 July 2018

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Leukemia-associated mutations within the NOTCH1 heterodimerization domain fall into at least two distinct mechanistic classes

5 July 2018

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5 July 2018

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5 July 2018

1 reference

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Notch1 promotes survival of E2A-deficient T cell lymphomas through pre-T cell receptor-dependent and -independent mechanisms.

5 July 2018

1 reference

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Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Notch1 mutations are important for leukemic transformation in murine models of precursor-T leukemia/lymphoma

5 July 2018

1 reference

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Activating Notch1 mutations in mouse models of T-ALL.

5 July 2018

1 reference

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5 July 2018

1 reference

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Hyperresponse to T-cell receptor signaling and apoptosis of Id1 transgenic thymocytes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Notch signaling controls multiple steps of pancreatic differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

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5 July 2018

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Massive apoptosis of thymocytes in T-cell-deficient Id1 transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Overexpression of the Helix-Loop-Helix protein Id2 blocks T cell development at multiple stages.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

The Tal1 oncoprotein inhibits E47-mediated transcription. Mechanism of inhibition

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

TAL1, TAL2 and LYL1: a family of basic helix-loop-helix proteins implicated in T cell acute leukaemia

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Positive and negative transcriptional control by the TAL1 helix-loop-helix protein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951.

5 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032944

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0032944

NF-kappaB activation in premalignant mouse tal-1/scl thymocytes and tumors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3290631

A reassessment of the effect of activated Notch1 on CD4 and CD8 T cell development

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22393458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Helix-loop-helix proteins regulate pre-TCR and TCR signaling through modulation of Rel/NF-kappaB activities

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22393458

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0032944

1 reference

31 July 2017

0 references

1 reference

31 July 2017

1 reference