(Q34190610)

31 July 2017

title

Identification of essential residues involved in the allosteric modulation of the human A(3) adenosine receptor (English)

1 reference

31 July 2017

Identification of Essential Residues Involved in the Allosteric Modulation of the Human A3Adenosine Receptor (English)

1 reference

Crossref

https://api.crossref.org/works/10.1124/MOL.63.5.1021

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/MOL.63.5.1021

24 December 2023

1 reference

https://api.crossref.org/works/10.1124/MOL.63.5.1021

24 December 2023

6

Kenneth A. Jacobson

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695530

24 December 2023

author name string

Zhan-Guo Gao

1

1 reference

31 July 2017

Soo-Kyung Kim

2

1 reference

31 July 2017

Aishe Chen

4

1 reference

31 July 2017

Ariel S. Gross

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695530

24 December 2023

Joshua B. Blaustein

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695530

24 December 2023

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12695530

24 December 2023

publication date

1 May 2003

1 reference

full work available at URL

31 July 2017

https://europepmc.org/articles/pmc4367541?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695530

https://europepmc.org/articles/PMC4367541

24 December 2023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695530

https://europepmc.org/articles/PMC4367541?pdf=render

24 December 2023

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12695530

https://syndication.highwire.org/content/doi/10.1124/mol.63.5.1021

24 December 2023

1 reference

Crossref

https://api.crossref.org/works/10.1124/MOL.63.5.1021

24 December 2023

published in

Molecular Pharmacology

1 reference

31 July 2017

volume

63

1 reference

31 July 2017

issue

5

1 reference

31 July 2017

page(s)

1021-1031

1 reference

Molecular Architecture of G Protein-Coupled Receptors.

31 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Allosteric binding sites on cell-surface receptors: novel targets for drug discovery

5 July 2018

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Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives

5 July 2018

1 reference

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G protein-coupled receptor allosterism and complexing

5 July 2018

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Identification by site-directed mutagenesis of residues involved in ligand recognition and activation of the human A3 adenosine receptor

5 July 2018

1 reference

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[(3)H]8-Ethyl-4-methyl-2-phenyl-(8R)-4,5,7,8-tetrahydro-1H-imidazo[2,1-i]-purin-5-one ([(3)H]PSB-11), a novel high-affinity antagonist radioligand for human A(3) adenosine receptors

5 July 2018

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Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides

5 July 2018

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Allosteric modulation of A(3) adenosine receptors by a series of 3-(2-pyridinyl)isoquinoline derivatives

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Multiple allosteric sites on muscarinic receptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Differential effects of the allosteric enhancer (2-amino-4,5-dimethyl-trienyl)[3-trifluoromethyl) phenyl]methanone (PD81,723) on agonist and antagonist binding and function at the human wild-type and a mutant (T277A) adenosine A1 receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

The binding-site crevice of the D4 dopamine receptor is coupled to three distinct sites of allosteric modulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Cooperative multi-modal sensing and therapeutic implications of the extracellular Ca(2+) sensing receptor

5 July 2018

1 reference

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Crystal structure of rhodopsin: A G protein-coupled receptor

5 July 2018

1 reference

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TinyGRAP database: a bioinformatics tool to mine G-protein-coupled receptor mutant data.

5 July 2018

1 reference

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Allosteric interactions at muscarinic cholinoceptors

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Site-directed mutagenesis of the human A1 adenosine receptor: influences of acidic and hydroxy residues in the first four transmembrane domains on ligand binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Mutational analysis of muscarinic acetylcholine receptors: structural basis of ligand/receptor/G protein interactions

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Role of acidic amino acids in the allosteric modulation by gallamine of antagonist binding at the m2 muscarinic acetylcholine receptor

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

5 July 2018

GABAA receptor channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Use of eukaryotic expression technology in the functional analysis of cloned genes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes.

5 July 2018

1 reference

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4367541

Differential allosteric modulation by amiloride analogues of agonist and antagonist binding at A(1) and A(3) adenosine receptors

5 July 2018

1 reference

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Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary

28 October 2018

1 reference

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Galantamine for Alzheimer's disease.

28 October 2018

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Deoxamuscaroneoxime derivatives as useful muscarinic agonists to explore the muscarinic subsite: demox, a modulator of orthosteric and allosteric sites at cardiac muscarinic M2 receptors

28 October 2018

1 reference

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Allosteric site on muscarinic acetylcholine receptors: a single amino acid in transmembrane region 7 is critical to the subtype selectivities of caracurine V derivatives and alkane-bisammonium ligands

28 October 2018

1 reference

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Modeling and mutational analysis of a putative sodium-binding pocket on the dopamine D2 receptor

28 October 2018

1 reference

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Agonist binding and function at the human alpha(2A)-adrenoceptor: allosteric modulation by amilorides.

28 October 2018

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A fast new approach to pharmacophore mapping and its application to dopaminergic and benzodiazepine agonists.

28 October 2018

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Site-directed mutagenesis reveals two epitopes involved in the subtype selectivity of the allosteric interactions of gallamine at muscarinic acetylcholine receptors

28 October 2018

1 reference

12 December 2020

Probing of the location of the allosteric site on m1 muscarinic receptors by site-directed mutagenesis

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12 December 2020

Homology modeling of the dopamine D2 receptor and its testing by docking of agonists and tricyclic antagonists

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12 December 2020

Pivotal role of an aspartate residue in sodium sensitivity and coupling to G proteins of neurotensin receptors

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12 December 2020

Allosteric modulation of A2A adenosine receptors by amiloride analogues and sodium ions

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12 December 2020

An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium

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12 December 2020

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

36

1 reference

Crossref

https://api.crossref.org/works/10.1124/MOL.63.5.1021

24 December 2023

Identifiers

1 reference

31 July 2017

1 reference

31 July 2017

1 reference