(Q34196216)

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Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Akt activation is a common event in pediatric malignant gliomas and a potential adverse prognostic marker: a report from the Children's Oncology Group (English)

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Peter C. Burger

3

object named as

Peter C Burger

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Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Ian F Pollack

1

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31 July 2017

Ronald L Hamilton

2

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31 July 2017

Daniel J Brat

4

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31 July 2017

Marc K Rosenblum

5

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31 July 2017

Geoffrey H Murdoch

6

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31 July 2017

Marina N Nikiforova

7

1 reference

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31 July 2017

Emiko J Holmes

8

1 reference

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31 July 2017

Tianni Zhou

9

1 reference

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31 July 2017

Kenneth J Cohen

10

1 reference

Europe PubMed Central

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31 July 2017

Regina I Jakacki

11

1 reference

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31 July 2017

Children's Oncology Group

12

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31 July 2017

publication date

4 July 2010

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Europe PubMed Central

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31 July 2017

Journal of Neuro-Oncology

1 reference

Europe PubMed Central

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31 July 2017

99

1 reference

Europe PubMed Central

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31 July 2017

2

1 reference

Europe PubMed Central

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31 July 2017

155-163

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Molecularly targeted therapies for malignant glioma: rationale for combinatorial strategies

1 reference

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5 July 2018

NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

1 reference

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5 July 2018

Take your PIK: phosphatidylinositol 3-kinase inhibitors race through the clinic and toward cancer therapy

1 reference

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5 July 2018

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

1 reference

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5 July 2018

An integrated genomic analysis of human glioblastoma multiforme

1 reference

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5 July 2018

Class I PI3 kinase inhibition by the pyridinylfuranopyrimidine inhibitor PI-103 enhances tumor radiosensitivity.

1 reference

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5 July 2018

Protein expression of platelet-derived growth factor receptor correlates with malignant histology and PTEN with survival in childhood gliomas

1 reference

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5 July 2018

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1 reference

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5 July 2018

A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma

1 reference

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5 July 2018

Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma

1 reference

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5 July 2018

Activation of Akt predicts poor outcome in neuroblastoma

1 reference

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5 July 2018

Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells

1 reference

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5 July 2018

Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma

1 reference

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5 July 2018

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

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5 July 2018

Determinants of rapamycin sensitivity in breast cancer cells

1 reference

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5 July 2018

Incidence, mechanism and prognostic value of activated AKT in pancreas cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

The influence of central review on outcome associations in childhood malignant gliomas: results from the CCG-945 experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Impact of proliferation index on outcome in childhood malignant gliomas: results in a multi-institutional cohort

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Local recurrence in head and neck cancer: relationship to radiation resistance and signal transduction.

1 reference

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5 July 2018

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Age and TP53 mutation frequency in childhood malignant gliomas: results in a multi-institutional cohort.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Preferential inactivation of the p53 tumor suppressor pathway and lack of EGFR amplification distinguish de novo high grade pediatric astrocytomas from de novo adult astrocytomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Progression as exemplified by human astrocytic tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Determination of p53 mutations, EGFR overexpression, and loss of p16 expression in pediatric glioblastomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

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PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2954435

5 July 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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Antigen retrieval in formalin-fixed, paraffin-embedded tissues: an enhancement method for immunohistochemical staining based on microwave oven heating of tissue sections

1 reference

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5 July 2018

Deregulation of the p14ARF/MDM2/p53 pathway is a prerequisite for human astrocytic gliomas with G1-S transition control gene abnormalities.

1 reference

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28 July 2018

Analysis of oncogene and tumor suppressor gene alterations in pediatric malignant astrocytomas reveals reduced survival for patients with PTEN mutations.

1 reference

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28 July 2018

Genetic alterations in pediatric high-grade astrocytomas.

1 reference

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1 reference

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Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity

1 reference

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Tyrosine kinase expression in pediatric high grade astrocytoma

1 reference

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1 reference

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PIK3CA gene mutations in pediatric and adult glioblastoma multiforme.

1 reference

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1 reference

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1 reference

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An immunochemical analysis of the human nuclear phosphoprotein p53. New monoclonal antibodies and epitope mapping using recombinant p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain tumors in children

1 reference

https://pubmed.ncbi.nlm.nih.gov/20607350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1007/S11060-010-0297-3

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Europe PubMed Central

PubMed publication ID

31 July 2017

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24 November 2022

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PMC publication ID

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Europe PubMed Central

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31 July 2017

PubMed publication ID

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Europe PubMed Central

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31 July 2017

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