(Q34196262)

31 July 2017

title

PTEN action in leukaemia dictated by the tissue microenvironment (English)

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31 July 2017

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14

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31 July 2017

Julie Teruya-Feldstein

11

object named as

Julie Teruya-Feldstein

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Cornelius Miething

1

object named as

Cornelius Miething

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author name string

Cornelius Miething

1

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31 July 2017

Claudio Scuoppo

2

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31 July 2017

Benedikt Bosbach

3

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31 July 2017

Iris Appelmann

4

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31 July 2017

Joy Nakitandwe

5

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31 July 2017

Jing Ma

6

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31 July 2017

Gang Wu

7

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31 July 2017

Laura Lintault

8

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31 July 2017

Martina Auer

9

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31 July 2017

Prem K Premsrirut

10

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31 July 2017

James Hicks

12

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31 July 2017

Helene Benveniste

13

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31 July 2017

James R Downing

15

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31 July 2017

Scott W Lowe

16

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31 July 2017

language of work or name

English

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publication date

4 May 2014

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31 July 2017

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31 July 2017

volume

510

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31 July 2017

issue

7505

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31 July 2017

page(s)

402-406

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Differential analysis of gene regulation at transcript resolution with RNA-seq

31 July 2017

cites work

1 reference

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28 July 2018

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28 July 2018

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Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence

28 July 2018

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A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.

28 July 2018

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PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis

28 July 2018

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28 July 2018

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PTEN loss in the continuum of common cancers, rare syndromes and mouse models.

28 July 2018

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Characterization of CCX282-B, an orally bioavailable antagonist of the CCR9 chemokine receptor, for treatment of inflammatory bowel disease

28 July 2018

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p53 loss promotes acute myeloid leukemia by enabling aberrant self-renewal

28 July 2018

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CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia

28 July 2018

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High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

28 July 2018

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Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

28 July 2018

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Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

Tenets of PTEN tumor suppression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

Molecular pathogenesis of T-cell leukaemia and lymphoma

28 July 2018

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Tissue-specific and reversible RNA interference in transgenic mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

The evolution of phosphatidylinositol 3-kinases as regulators of growth and metabolism

28 July 2018

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Mouse genomic representational oligonucleotide microarray analysis: detection of copy number variations in normal and tumor specimens

28 July 2018

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

28 July 2018

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Probing tumor phenotypes using stable and regulated synthetic microRNA precursors

28 July 2018

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

Design of a genome-wide siRNA library using an artificial neural network

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

TECK, an efficacious chemoattractant for human thymocytes, uses GPR-9-6/CCR9 as a specific receptor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

Pten is essential for embryonic development and tumour suppression

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

Doxycycline-mediated quantitative and tissue-specific control of gene expression in transgenic mice

28 July 2018

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More powerful procedures for multiple significance testing

28 July 2018

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Vav promoter-tTA conditional transgene expression system for hematopoietic cells drives high level expression in developing B and T cells.

28 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13239

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13239

The genetic basis of early T-cell precursor acute lymphoblastic leukaemia

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13239

Two genetically separable steps in the differentiation of thymic epithelium.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13239

A role for CCR9 in T lymphocyte development and migration.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13239

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

21 January 2018

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Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells

21 January 2018

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A systemically-administered small molecule antagonist of CCR9 acts as a tissue-selective inhibitor of lymphocyte trafficking

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE13239

Activating Notch1 mutations in mouse models of T-ALL.

21 January 2018

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GSEA-P: a desktop application for Gene Set Enrichment Analysis.

21 January 2018

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GSK-1605786, a selective small-molecule antagonist of the CCR9 chemokine receptor for the treatment of Crohn's disease.

21 January 2018

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Intestinal attraction: CCL25 functions in effector lymphocyte recruitment to the small intestine

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/- mice

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4165899

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

28 October 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE13239

Immature thymocytes employ distinct signaling pathways for allelic exclusion versus differentiation and expansion

21 January 2018

1 reference

12 December 2020

Chemokines define distinct microenvironments in the developing thymus

1 reference

12 December 2020

Deregulation of c-myc by translocation of the alpha-locus of the T-cell receptor in T-cell leukemias

1 reference

12 December 2020

Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia

1 reference

12 December 2020

Identifiers

DOI

10.1038/NATURE13239

1 reference

Dimensions Publication ID

31 July 2017

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31 July 2017

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