(Q34199692)

31 July 2017

1 reference

title

The impact of acetylation and deacetylation on the p53 pathway (English)

1 reference

31 July 2017

Christopher L Brooks

1

1 reference

31 July 2017

Wei Gu

series ordinal

2

1 reference

31 July 2017

publication date

1 June 2011

1 reference

31 July 2017

1 reference

31 July 2017

volume

2

1 reference

31 July 2017

issue

6

1 reference

31 July 2017

page(s)

456-462

1 reference

https://scigraph.springernature.com/pub.10.1007/s13238-011-1063-9

31 July 2017

exact match

0 references

cites work

SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

The first 30 years of p53: growing ever more complex

28 July 2018

1 reference

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

28 July 2018

Modes of p53 regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

MSL2 promotes Mdm2-independent cytoplasmic localization of p53

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Combinatorial patterns of histone acetylations and methylations in the human genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Acetylation is indispensable for p53 activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Negative regulation of the deacetylase SIRT1 by DBC1

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

An acetylation switch in p53 mediates holo-TFIID recruitment

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

SIRT1 regulates the function of the Nijmegen breakage syndrome protein

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

ASPP: a new family of oncogenes and tumour suppressor genes

28 July 2018

1 reference

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Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1).

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

p53 ubiquitination: Mdm2 and beyond

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Calorie restriction, SIRT1 and metabolism: understanding longevity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Transcriptional regulatory code of a eukaryotic genome

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Inhibition of p53 degradation by Mdm2 acetylation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Telomeres, stem cells, senescence, and cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Polyubiquitination of p53 by a ubiquitin ligase activity of p300.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Histone deacetylases (HDACs): characterization of the classical HDAC family

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

p53 mutant mice that display early ageing-associated phenotypes

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Negative control of p53 by Sir2alpha promotes cell survival under stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Deacetylation of p53 modulates its effect on cell growth and apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

CBP/p300 in cell growth, transformation, and development

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

DNA damage activates p53 through a phosphorylation-acetylation cascade

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3690542

Post-translational modifications and activation of p53 by genotoxic stresses

28 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Lessons from interconnected ubiquitylation and acetylation of p53: think metastable networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

The ubiquitin ligase COP1 is a critical negative regulator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

DBC1 is a negative regulator of SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Acetylation of p53 inhibits its ubiquitination by Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Histone acetylation: where to go and how to get there

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

The INK4a/ARF network in tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Acetylation of the p53 DNA-binding domain regulates apoptosis induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13238-011-1063-9

Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21748595

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S13238-011-1063-9

1 reference

Dimensions Publication ID

31 July 2017

0 references

1 reference

31 July 2017

1 reference