(Q34221738)

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Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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based on heuristic

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based on heuristic

lymphoblastic leukemia

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based on heuristic

pharmacokinetics

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based on heuristic

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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28 January 2020

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28 January 2020

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ORCID Public Data File 2021

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Ingrid Boehm

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28 January 2020

Clinton F Stewart

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Clinton F Stewart

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28 January 2020

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Hernan Carol

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28 January 2020

Barbara Szymanska

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Barbara Szymanska

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28 January 2020

Urszula Wilczynska-Kalak

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Urszula Wilczynska-Kalak

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28 January 2020

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Natalia L M Liem

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28 January 2020

Daniel Groepper

7

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28 January 2020

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29 March 2012

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28 January 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

7

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

e33894

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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Creative Commons Attribution 4.0 International

29 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Biology, risk stratification, and therapy of pediatric acute leukemias: an update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Recent research advances in childhood acute lymphoblastic leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

The Bcl-2 homology domain 3 mimetic ABT-737 targets the apoptotic machinery in acute lymphoblastic leukemia resulting in synergistic in vitro and in vivo interactions with established drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Bcl-2 inhibitors: targeting mitochondrial apoptotic pathways in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Bcl-2 inhibitors: small molecules with a big impact on cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Initial testing (stage 1) of the BH3 mimetic ABT-263 by the pediatric preclinical testing program

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

BCL-2 dependence and ABT-737 sensitivity in acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Credentialing preclinical pediatric xenograft models using gene expression and tissue microarray analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Pharmacological and clinical evaluation of L-asparaginase in the treatment of leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Long-term follow-up of people who have survived cancer during childhood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Childhood acute lymphoblastic leukaemia and relapse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

DIMSCAN: a microcomputer fluorescence-based cytotoxicity assay for preclinical testing of combination chemotherapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Pharmacokinetic/pharmacodynamic relationships of asparaginase formulations: the past, the present and recommendations for the future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Therapeutic synergy of oral taxane BMS-275183 and cetuximab versus human tumor xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Can the pharmaceutical industry reduce attrition rates?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Integrating pharmacology and in vivo cancer models in preclinical and clinical drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Microtubules as a target for anticancer drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Monitoring of Erwinia asparaginase therapy in childhood ALL in the Nordic countries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Pharmacokinetic approach to rational therapeutic doses for human tumor-bearing nude mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3315513

28 July 2018

Outcome of patients treated for relapsed or refractory acute lymphoblastic leukemia: a Therapeutic Advances in Childhood Leukemia Consortium study

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Childhood all blasts retain phenotypic and genotypic characteristics upon long-term serial passage in NOD/SCID mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Characterization of childhood acute lymphoblastic leukemia xenograft models for the preclinical evaluation of new therapies

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Activity of vincristine, L-ASP, and dexamethasone against acute lymphoblastic leukemia is enhanced by the BH3-mimetic ABT-737 in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

The pharmacokinetic profiles of dexamethasone and methylprednisolone concentration in perilymph and plasma following systemic and local administration

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Asparaginase may influence dexamethasone pharmacokinetics in acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Divergent mechanisms of glucocorticoid resistance in experimental models of pediatric acute lymphoblastic leukemia.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Vincristine pharmacokinetics is related to clinical outcome in children with standard risk acute lymphoblastic leukemia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Dexamethasone as a probe for vinorelbine clearance

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Pharmacokinetics, pharmacodynamics, efficacy, and safety of a new recombinant asparaginase preparation in children with previously untreated acute lymphoblastic leukemia: a randomized phase 2 clinical trial

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0033894

21 January 2018

Bim and Bad mediate imatinib-induced killing of Bcr/Abl+ leukemic cells, and resistance due to their loss is overcome by a BH3 mimetic.

1 reference

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21 January 2018

Nonparametric Estimation from Incomplete Observations

1 reference

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21 January 2018

Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference

1 reference

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A phase II trial of arsenic trioxide for relapsed and refractory acute lymphoblastic leukemia.

1 reference

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1 reference

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28 October 2018

Growth of human T-cell lineage acute leukemia in severe combined immunodeficiency (SCID) mice and non-obese diabetic SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Good engraftment of B-cell precursor ALL in NOD-SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between topotecan systemic exposure and tumor response in human neuroblastoma xenografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of human B-cell precursor leukemia in SCID mice by using a combination of the anti-CD19 immunotoxin B43-PAP with the standard chemotherapeutic drugs vincristine, methylprednisolone, and L-asparaginase

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monitoring of engraftment and progression of acute lymphoblastic leukemia in individual NOD/SCID mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transition of pemphigus vulgaris into pemphigus foliaceus confirmed by antidesmoglein ELISA profile

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vincristine in childhood leukaemia: no pharmacokinetic rationale for dose reduction in adolescents

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term follow-up of relapsed childhood acute lymphoblastic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22479469

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0033894

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

2012PLoSO...733894S

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22479469%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

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