(Q24337209)

5

object named as

Margaret Shipp

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author name string

Jing Deng

1

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Nicole Carlson

2

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Kunihiko Takeyama

3

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Paola Dal Cin

Antiapoptotic BCL-2 is required for maintenance of a model leukemia

4

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language of work or name

English

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publication date

August 2007

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published in

Cancer Cell

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volume

12

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page(s)

171-85

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issue

2

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cites work

1 reference

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7 January 2021

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

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7 January 2021

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

1 reference

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7 January 2021

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

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7 January 2021

An Mll-dependent Hox program drives hematopoietic progenitor expansion

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7 January 2021

The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA.

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7 January 2021

Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function

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7 January 2021

BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly

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7 January 2021

BH3-Only proteins-essential initiators of apoptotic cell death

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7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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7 January 2021

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

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7 January 2021

Cell death: critical control points

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7 January 2021

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

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Bcl-2-family proteins: the role of the BH3 domain in apoptosis.

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7 January 2021

BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis

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7 January 2021

A matter of life and death

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7 January 2021

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

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7 January 2021

Bax-independent inhibition of apoptosis by Bcl-XL.

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7 January 2021

X-ray and NMR structure of human Bcl-xL, an inhibitor of programmed cell death

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7 January 2021

Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.

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7 January 2021

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

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7 January 2021

Role of Bax and Bak in mitochondrial morphogenesis

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7 January 2021

Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies

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7 January 2021

Modelling the molecular circuitry of cancer

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7 January 2021

The Bcl2 family: regulators of the cellular life-or-death switch

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7 January 2021

'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.

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7 January 2021

miR-15 and miR-16 induce apoptosis by targeting BCL2

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7 January 2021

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1 reference

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7 January 2021

Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis

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7 January 2021

Nonionic detergents induce dimerization among members of the Bcl-2 family

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7 January 2021

Abrogation of mitochondrial cytochrome c release and caspase-3 activation in acquired multidrug resistance.

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7 January 2021

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

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7 January 2021

Alkylating DNA damage stimulates a regulated form of necrotic cell death

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https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

BCL-2 family members and the mitochondria in apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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7 January 2021

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

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https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

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https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

The pathophysiology of mitochondrial cell death

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Involvement of the bcl-2 gene in human follicular lymphoma

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7 January 2021

Bad is a BH3 domain-containing protein that forms an inactivating dimer with Bcl-XL.

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https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

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7 January 2021

Pharmacological manipulation of Bcl-2 family members to control cell death

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https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

Clinical significance of bcl2 and p53 protein expression in diffuse large B-cell lymphoma: a population-based study.

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

BCL2 expression is a prognostic marker for the activated B-cell-like type of diffuse large B-cell lymphoma

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021

BH3 domains as BCL-2 inhibitors: prototype cancer therapeutics

1 reference

https://api.crossref.org/works/10.1016%2FJ.CCR.2007.07.001

7 January 2021