(Q34224255)

31 July 2017

1 reference

title

Tissue-specific insulin resistance in type 2 diabetes: lessons from gene-targeted mice (English)

1 reference

31 July 2017

0 references

1 reference

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Nakae J

1

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31 July 2017

Kido Y

series ordinal

2

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31 July 2017

Accili D

series ordinal

3

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31 July 2017

language of work or name

English

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publication date

1 February 2001

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31 July 2017

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31 July 2017

volume

33

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31 July 2017

issue

1

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31 July 2017

page(s)

22-27

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Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes

31 July 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Genetics of non-insulin-dependent (type-II) diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Genetic dissection of complex traits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

The IRS-signalling system in insulin and cytokine action

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

The IRS-signalling system: a network of docking proteins that mediate insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Differential regulation of gene expression by insulin and IGF-1 receptors correlates with phosphorylation of a single amino acid residue in the forkhead transcription factor FKHR

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

The differential effects of pp120 (Ceacam 1) on the mitogenic action of insulin and insulin-like growth factor 1 are regulated by the nonconserved tyrosine 1316 in the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

CAP defines a second signalling pathway required for insulin-stimulated glucose transport

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Genetic modifiers of the insulin resistance phenotype in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Disruption of IRS-2 causes type 2 diabetes in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Contrasting effects of IRS-1 versus IRS-2 gene disruption on carbohydrate and lipid metabolism in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Insulin receptor substrate-2 amino acid polymorphisms are not associated with random type 2 diabetes among Caucasians

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Interaction of insulin receptor substrate 3 with insulin receptor, insulin receptor-related receptor, insulin-like growth factor-1 receptor, and downstream signaling proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Insulin receptor substrate 3 is not essential for growth or glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Deconstructing type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Type 2 diabetes--who is conducting the orchestra?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Type 2 diabetes: when insulin secretion fails to compensate for insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Insights into insulin resistance and type 2 diabetes from knockout mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Central role of the adipocyte in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Banting Lecture 1997. Control of glucose uptake and release by the liver in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Free fatty acids and pathogenesis of type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Obesity, diabetes and the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Role of brain insulin receptor in control of body weight and reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

Evidence that IRS-2 phosphorylation is required for insulin action in hepatocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F07853890109002056

10.3109/07853890109002056

21 January 2018

Identifiers

DOI

1 reference

release_qggoqpuzeverdp5oib7crptjyi

31 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/qggoqpuzeverdp5oib7crptjyi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference