(Q34235817)

31 July 2017

title

Gene Expression Changes Induced by PPAR Gamma Agonists in Animal and Human Liver (English)

1 reference

31 July 2017

Alexandra Rogue

1

1 reference

31 July 2017

Catherine Spire

2

1 reference

31 July 2017

Manuel Brun

3

1 reference

31 July 2017

Nancy Claude

4

1 reference

31 July 2017

André Guillouzo

5

1 reference

31 July 2017

publication date

19 October 2010

1 reference

31 July 2017

1 reference

31 July 2017

volume

2010

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31 July 2017

page(s)

325183

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Creative Commons Attribution 3.0 Unported

31 July 2017

copyright license

start time

1 January 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Adipocyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Activation of peroxisome proliferator-activated receptor-gamma stimulates the growth arrest and DNA-damage inducible 153 gene in non-small cell lung carcinoma cells

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Diabetic KKAy mice exhibit increased hepatic PPARgamma1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones

6 July 2018

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Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Down-regulation by troglitazone of hepatic tumor necrosis factor-alpha and interleukin-6 mRNA expression in a murine model of non-insulin-dependent diabetes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Troglitazone induces expression of PPARgamma in liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Clinical pharmacokinetics of troglitazone

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Rosiglitazone (BRL49653), a PPARgamma-selective agonist, causes peroxisome proliferator-like liver effects in obese mice

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Liver cell models in in vitro toxicology

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

The peroxisome proliferator-activated receptor-gamma is a negative regulator of macrophage activation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Troglitazone action is independent of adipose tissue

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Tissue distribution and quantification of the expression of mRNAs of peroxisome proliferator-activated receptors and liver X receptor-alpha in humans: no alteration in adipose tissue of obese and NIDDM patients

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

The organization, promoter analysis, and expression of the human PPARgamma gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Regulation of PPAR gamma gene expression by nutrition and obesity in rodents.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Differential activation of adipogenesis by multiple PPAR isoforms.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells.

6 July 2018

1 reference

https://api.crossref.org/works/10.1155%2F2010%2F325183

Identification of promethin and PGLP as two novel up-regulated genes in PPARgamma1-induced adipogenic mouse liver

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Liver peroxisome proliferator-activated receptor gamma contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass.

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Species-specific toxicity of diclofenac and troglitazone in primary human and rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Troglitazone enhances the hepatotoxicity of acetaminophen by inducing CYP3A in rats

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Distribution of peroxisome proliferator-activated receptors (PPARs) in human skeletal muscle and adipose tissue: relation to insulin action

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Selective activation of PPARgamma in skeletal muscle induces endogenous production of adiponectin and protects mice from diet-induced insulin resistance

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Troglitazone but not rosiglitazone induces G1 cell cycle arrest and apoptosis in human and rat hepatoma cell lines

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Applications of microarrays with toxicologically relevant genes (tox genes) for the evaluation of chemical toxicants in Sprague Dawley rats in vivo and human hepatocytes in vitro

21 January 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2963138

Effects of Chronic Rosiglitazone Therapy on Gene Expression in Human Adipose Tissuein Vivoin Patients with Type 2 Diabetes

28 October 2018

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https://api.crossref.org/works/10.1155%2F2010%2F325183

Hepatic dysfunction associated with troglitazone

21 January 2018

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12 December 2020

Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones

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12 December 2020

Evolving concepts in liver tissue modeling and implications for in vitro toxicology

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12 December 2020

Insulin sensitization in diabetic rat liver by an antihyperglycemic agent

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12 December 2020

Troglitazone increases cytochrome P-450 3A protein and activity in primary cultures of human hepatocytes

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12 December 2020

Up-regulation of peroxisome proliferator-activated receptors (PPAR-alpha) and PPAR-gamma messenger ribonucleic acid expression in the liver in murine obesity: troglitazone induces expression of PPAR-gamma-responsive adipose tissue-specific genes in

1 reference

12 December 2020

Evidence for peroxisome proliferator-activated receptor (PPAR)alpha-independent peroxisome proliferation: effects of PPARgamma/delta-specific agonists in PPARalpha-null mice

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12 December 2020

The role of conjugation in hepatotoxicity of troglitazone in human and porcine hepatocyte cultures

1 reference

12 December 2020

Gene expression analysis reveals chemical-specific profiles

1 reference

12 December 2020

Alteration in expression profiles of a series of diabetes-related genes in db/db mice following treatment with thiazolidinediones

1 reference

12 December 2020

Identifiers

DOI

10.1155/2010/325183

1 reference

31 July 2017

1 reference

31 July 2017

1 reference