(Q44419375)

2 December 2017

title

Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells (English)

1 reference

2 December 2017

main subject

hepatocellular carcinoma

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717389

28 December 2023

3

Motoaki Ohtsubo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A12717389

28 December 2023

author name string

Hironori Koga

1

1 reference

2 December 2017

Masaru Harada

2

1 reference

2 December 2017

Shoichiro Shishido

4

1 reference

2 December 2017

Hiroto Kumemura

5

1 reference

2 December 2017

Shinichiro Hanada

6

1 reference

2 December 2017

Eitaro Taniguchi

7

1 reference

2 December 2017

Katsumi Yamashita

8

1 reference

2 December 2017

Ryukichi Kumashiro

9

1 reference

2 December 2017

Takato Ueno

10

1 reference

2 December 2017

Michio Sata

11

1 reference

2 December 2017

language of work or name

English

0 references

publication date

1 May 2003

1 reference

full work available at URL

2 December 2017

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1053%2Fjhep.2003.50186

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

https://onlinelibrary.wiley.com/doi/full/10.1053/jhep.2003.50186

28 December 2023

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

28 December 2023

1 reference

2 December 2017

volume

37

1 reference

2 December 2017

issue

5

1 reference

2 December 2017

page(s)

1086-1096

1 reference

Peroxisome proliferator-activated receptors, coactivators, and downstream targets

2 December 2017

cites work

1

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

New drug targets for type 2 diabetes and the metabolic syndrome

28 December 2023

2

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

28 December 2023

3

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Induction of solid tumor differentiation by the peroxisome proliferator-activated receptor-gamma ligand troglitazone in patients with liposarcoma

28 December 2023

4

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Ligands for peroxisome proliferator-activated receptorgamma and retinoic acid receptor inhibit growth and induce apoptosis of human breast cancer cells in vitro and in BNX mice

28 December 2023

5

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

28 December 2023

8

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Cyclin-dependent regulation of G1 in mammalian fibroblasts.

28 December 2023

9

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Cyclin dependent kinase regulation

28 December 2023

10

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Inhibitors of mammalian G1 cyclin-dependent kinases

28 December 2023

11

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Role of PPARgamma in regulating a cascade expression of cyclin-dependent kinase inhibitors, p18(INK4c) and p21(Waf1/Cip1), during adipogenesis

28 December 2023

12

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines

28 December 2023

13

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

New insights into the tumor suppression function of P27(kip1)

28 December 2023

14

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

High level expression of p27(kip1) and cyclin D1 in some human breast cancer cells: inverse correlation between the expression of p27(kip1) and degree of malignancy in human breast and colorectal cancers

28 December 2023

15

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas.

28 December 2023

16

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

The murine gene p27Kip1 is haplo-insufficient for tumour suppression

28 December 2023

17

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

28 December 2023

18

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

28 December 2023

19

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

28 December 2023

20

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

28 December 2023

21

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

28 December 2023

22

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

28 December 2023

23

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Establishment of two distinct human hepatocellular carcinoma cell lines from a single nodule showing clonal dedifferentiation of cancer cells

28 December 2023

24

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

A novel method for real time quantitative RT-PCR.

28 December 2023

26

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Real-time quantitative RT-PCR after laser-assisted cell picking

28 December 2023

27

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2

28 December 2023

28

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.

28 December 2023

29

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Efficient selection for high-expression transfectants with a novel eukaryotic vector

28 December 2023

30

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Ubiquitination and degradation of the substrate recognition subunits of SCF ubiquitin-protein ligases

28 December 2023

31

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Growth inhibition and differentiation of pancreatic cancer cell lines by PPAR gamma ligand troglitazone

28 December 2023

32

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

PPARgamma ligands suppress proliferation of human urothelial basal cells in vitro

28 December 2023

33

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

28 December 2023

34

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

28 December 2023

35

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Retinoic acid-mediated growth arrest requires ubiquitylation and degradation of the F-box protein Skp2.

28 December 2023

36

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

28 December 2023

37

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Skp2 is oncogenic and overexpressed in human cancers

28 December 2023

38

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Role of the F-box protein Skp2 in lymphomagenesis

28 December 2023

39

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Adenomatous hyperplasia in the vicinity of small hepatocellular carcinoma

28 December 2023

40

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation

28 December 2023

41

1 reference

https://api.crossref.org/works/10.1053/JHEP.2003.50186

28 December 2023

Identifiers

1 reference

2 December 2017

1 reference