(Q34237789)

English

Abundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogen

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scholarly article

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Europe PubMed Central

PubMed publication ID

31 July 2017

Abundant and diverse clustered regularly interspaced short palindromic repeat spacers in Clostridium difficile strains and prophages target multiple phage types within this pathogen (English)

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Europe PubMed Central

PubMed publication ID

31 July 2017

Clostridium difficile

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4

object named as

Martha R J Clokie

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Europe PubMed Central

PubMed publication ID

31 July 2017

3

object named as

Trevor D Lawley

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

author name string

Katherine R Hargreaves

1

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Cesar O Flores

2

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

publication date

26 August 2014

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Europe PubMed Central

PubMed publication ID

31 July 2017

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

e01045-13

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

Clostridium difficile phages: still difficult?

1 reference

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Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins.

1 reference

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Phage ϕC2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains

1 reference

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6 July 2018

MEGA6: Molecular Evolutionary Genetics Analysis version 6.0

1 reference

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Dealing with the evolutionary downside of CRISPR immunity: bacteria and beneficial plasmids

1 reference

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Type I-E CRISPR-cas systems discriminate target from non-target DNA through base pairing-independent PAM recognition

1 reference

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6 July 2018

Genetically diverse Clostridium difficile strains harboring abundant prophages in an estuarine environment

1 reference

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6 July 2018

Rapid evolution of the human gut virome

1 reference

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6 July 2018

Genome-wide identification of regulatory RNAs in the human pathogen Clostridium difficile.

1 reference

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6 July 2018

The susceptibility of Pseudomonas aeruginosa strains from cystic fibrosis patients to bacteriophages.

1 reference

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6 July 2018

Cytotoxic chromosomal targeting by CRISPR/Cas systems can reshape bacterial genomes and expel or remodel pathogenicity islands

1 reference

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6 July 2018

CRISPRTarget: bioinformatic prediction and analysis of crRNA targets.

1 reference

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6 July 2018

A bacteriophage encodes its own CRISPR/Cas adaptive response to evade host innate immunity

1 reference

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6 July 2018

Protospacer recognition motifs: mixed identities and functional diversity

1 reference

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6 July 2018

Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system.

1 reference

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6 July 2018

Emergence and global spread of epidemic healthcare-associated Clostridium difficile

1 reference

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6 July 2018

Consequences of Clostridium difficile infection: understanding the healthcare burden

1 reference

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6 July 2018

The CRISPR/Cas adaptive immune system of Pseudomonas aeruginosa mediates resistance to naturally occurring and engineered phages

1 reference

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Selective and hyperactive uptake of foreign DNA by adaptive immune systems of an archaeon via two distinct mechanisms.

1 reference

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6 July 2018

Multiscale model of CRISPR-induced coevolutionary dynamics: diversification at the interface of Lamarck and Darwin

1 reference

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6 July 2018

CRISPR targeting reveals a reservoir of common phages associated with the human gut microbiome

1 reference

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6 July 2018

Prophage carriage and diversity within clinically relevant strains of Clostridium difficile

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Intricate interactions between the bloom-forming cyanobacterium Microcystis aeruginosa and foreign genetic elements, revealed by diversified clustered regularly interspaced short palindromic repeat (CRISPR) signatures

1 reference

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6 July 2018

Ultrafast evolution and loss of CRISPRs following a host shift in a novel wildlife pathogen, Mycoplasma gallisepticum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

CRISPR: new horizons in phage resistance and strain identification

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

The Pfam protein families database

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

The human gut virome: inter-individual variation and dynamic response to diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Structure-Based Modification of a Clostridium difficile-Targeting Endolysin Affects Activity and Host Range

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

PHAST: a fast phage search tool

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence

1 reference

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CRISPR inhibition of prophage acquisition in Streptococcus pyogenes

1 reference

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6 July 2018

Evolution and classification of the CRISPR-Cas systems

1 reference

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6 July 2018

CRISPR distribution within the Escherichia coli species is not suggestive of immunity-associated diversifying selection.

1 reference

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6 July 2018

The Escherichia coli CRISPR system protects from λ lysogenization, lysogens, and prophage induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Bacteriophage treatment significantly reduces viable Clostridium difficile and prevents toxin production in an in vitro model system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

progressiveMauve: multiple genome alignment with gene gain, loss and rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

The small, slow and specialized CRISPR and anti-CRISPR of Escherichia and Salmonella

1 reference

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6 July 2018

Genome analysis of the Clostridium difficile phage PhiCD6356, a temperate phage of the Siphoviridae family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Diversity of CRISPR loci in Escherichia coli

1 reference

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6 July 2018

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1 reference

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6 July 2018

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1 reference

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6 July 2018

Analysis of CRISPR in Streptococcus mutans suggests frequent occurrence of acquired immunity against infection by M102-like bacteriophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Defining the mobilome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

CRISPR families of the crenarchaeal genus Sulfolobus: bidirectional transcription and dynamic properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Molecular characterization of a Clostridium difficile bacteriophage and its cloned biologically active endolysin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

CRISPRcompar: a website to compare clustered regularly interspaced short palindromic repeats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

MEGA: a biologist-centric software for evolutionary analysis of DNA and protein sequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

CRISPR--a widespread system that provides acquired resistance against phages in bacteria and archaea

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

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Diversity, activity, and evolution of CRISPR loci in Streptococcus thermophilus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

CRISPRFinder: a web tool to identify clustered regularly interspaced short palindromic repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

The CRISPRdb database and tools to display CRISPRs and to generate dictionaries of spacers and repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Evolutionary conservation of sequence and secondary structures in CRISPR repeats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

The complete genome sequence of Clostridium difficile phage phiC2 and comparisons to phiCD119 and inducible prophages of CD630.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Genomic organization and molecular characterization of Clostridium difficile bacteriophage PhiCD119.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Clustered regularly interspaced short palindrome repeats (CRISPRs) have spacers of extrachromosomal origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

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CRISPR elements in Yersinia pestis acquire new repeats by preferential uptake of bacteriophage DNA, and provide additional tools for evolutionary studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Isolation and characterization of temperate bacteriophages of Clostridium difficile.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Mauve: multiple alignment of conserved genomic sequence with rearrangements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

WebLogo: A Sequence Logo Generator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Identification of genes that are associated with DNA repeats in prokaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

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1 reference

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Evidence for nucleic acid binding ability and nucleosome association of Bombyx mori nucleopolyhedrovirus BRO proteins

1 reference

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Primer3 on the WWW for general users and for biologist programmers

1 reference

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6 July 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

6 July 2018

Sequence logos: a new way to display consensus sequences

1 reference

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6 July 2018

Evaluation of bacteriophage therapy to control Clostridium difficile and toxin production in an in vitro human colon model system.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

28 October 2018

Evidence of in vivo prophage induction during Clostridium difficile infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

28 October 2018

Prophage-stimulated toxin production in Clostridium difficile NAP1/027 lysogens.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

28 October 2018

Comparative analysis of CRISPR loci in lactic acid bacteria genomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4173771

28 October 2018

Effect of phage infection on toxin production by Clostridium difficile

1 reference

https://pubmed.ncbi.nlm.nih.gov/25161187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The distribution of Clostridium difficile in the environment of South Wales.

1 reference

https://pubmed.ncbi.nlm.nih.gov/25161187

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MBIO.01045-13

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

31 July 2017

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