(Q34269340)

1 August 2017

title

Protective effect of metabotropic glutamate mGluR5 receptor elimination in a 6-hydroxydopamine model of Parkinson's disease (English)

1 reference

1 August 2017

1 reference

Michael A Schwarzschild

6

object named as

Michael A Schwarzschild

1 reference

1 August 2017

Danqing Xiao

2

1 reference

1 August 2017

Daniela Pellegrino

3

1 reference

1 August 2017

Anil Kachroo

4

1 reference

1 August 2017

Anna-Liisa Brownell

5

1 reference

1 August 2017

Yolanda D. Black

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

16 July 2024

language of work or name

English

0 references

publication date

18 September 2010

1 reference

full work available at URL

1 August 2017

https://europepmc.org/articles/pmc2970925?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20854878/?tool=EBI

16 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20854878/pdf/?tool=EBI

16 July 2024

file format

Portable Document Format

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

https://europepmc.org/articles/PMC2970925

16 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

https://europepmc.org/articles/PMC2970925?pdf=render

16 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

https://doi.org/10.1016/j.neulet.2010.09.043

16 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20854878

https://api.elsevier.com/content/article/PII:S0304394010012607?httpAccept=text/xml

16 July 2024

1 reference

10.1016/J.NEULET.2010.09.043

Crossref

DOI

https://api.crossref.org/works/10.1016/J.NEULET.2010.09.043

https://api.elsevier.com/content/article/PII:S0304394010012607?httpAccept=text/plain

16 July 2024

1 reference

10.1016/J.NEULET.2010.09.043

Crossref

DOI

https://api.crossref.org/works/10.1016/J.NEULET.2010.09.043

16 July 2024

1 reference

1 August 2017

volume

486

1 reference

1 August 2017

issue

3

1 reference

1 August 2017

page(s)

161-165

1 reference

A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys

1 August 2017

cites work

1 reference

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Effects of early and delayed treatment with an mGluR5 antagonist on motor impairment, nigrostriatal damage and neuroinflammation in a rodent model of Parkinson's disease

6 July 2018

1 reference

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Tests to assess motor phenotype in mice: a user's guide

6 July 2018

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Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease

6 July 2018

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Distinct roles of group I mGlu receptors in striatal function

6 July 2018

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Enhanced binding of metabotropic glutamate receptor type 5 (mGluR5) PET tracers in the brain of parkinsonian primates

6 July 2018

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Mood disorders: regulation by metabotropic glutamate receptors

6 July 2018

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Targeting adenosine A2A receptors in Parkinson's disease

6 July 2018

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Prolonged blockade of NMDA or mGluR5 glutamate receptors reduces nigrostriatal degeneration while inducing selective metabolic changes in the basal ganglia circuitry in a rodent model of Parkinson's disease

6 July 2018

1 reference

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Interactions between metabotropic glutamate 5 and adenosine A2A receptors in normal and parkinsonian mice

6 July 2018

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Neuroprotective activity of the mGluR5 antagonists MPEP and MTEP against acute excitotoxicity differs and does not reflect actions at mGluR5 receptors

6 July 2018

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Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP.

6 July 2018

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The adenosine A(2A) receptor as an attractive target for Parkinson's disease treatment

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Ionotropic and metabotropic GABA and glutamate receptors in primate basal ganglia.

6 July 2018

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Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.

6 July 2018

1 reference

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Subthalamic infusion of an NMDA antagonist prevents basal ganglia metabolic changes and nigral degeneration in a rodent model of Parkinson's disease

6 July 2018

1 reference

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Differential subcellular localization of mGluR1a and mGluR5 in the rat and monkey Substantia nigra.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

mGluR5 antagonists 2-methyl-6-(phenylethynyl)-pyridine and (E)-2-methyl-6-(2-phenylethenyl)-pyridine reduce traumatic neuronal injury in vitro and in vivo by antagonizing N-methyl-D-aspartate receptors

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Immunohistochemical localization of a metabotropic glutamate receptor, mGluR5, in the rat brain

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Retrograde degeneration of nigrostriatal neurons induced by intrastriatal 6-hydroxydopamine injection in rats

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Reduction of L-DOPA-induced dyskinesia by the selective metabotropic glutamate receptor 5 antagonist 3-[(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Effect of L-Dopa on metabotropic glutamate receptor 5 in the brain of parkinsonian monkeys

28 October 2018

1 reference

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Modulation of dopaminergic and glutamatergic brain function: PET studies on parkinsonian rats

28 October 2018

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Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Forebrain adenosine A2A receptors contribute to L-3,4-dihydroxyphenylalanine-induced dyskinesia in hemiparkinsonian mice.

28 October 2018

1 reference

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Pharmacological activation of mGlu4 metabotropic glutamate receptors reduces nigrostriatal degeneration in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.

28 October 2018

1 reference

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Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease

28 October 2018

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Neuroprotective effects of metabotropic glutamate receptor ligands in a 6-hydroxydopamine rodent model of Parkinson's disease.

28 October 2018

1 reference

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Neuroprotective effects of the mGlu5R antagonist MPEP towards quinolinic acid-induced striatal toxicity: involvement of pre- and post-synaptic mechanisms and lack of direct NMDA blocking activity

28 October 2018

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Simultaneous blockade of adenosine A2A and metabotropic glutamate mGlu5 receptors increase their efficacy in reversing Parkinsonian deficits in rats.

28 October 2018

1 reference

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Endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the development of nigro-striatal damage induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.

28 October 2018

1 reference

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Progressive and extensive dopaminergic degeneration induced by convection-enhanced delivery of 6-hydroxydopamine into the rat striatum: a novel rodent model of Parkinson disease.

28 October 2018

1 reference

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Chronic but not acute treatment with a metabotropic glutamate 5 receptor antagonist reverses the akinetic deficits in a rat model of parkinsonism.

28 October 2018

1 reference

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Persistent behavioral sensitization to chronic L-DOPA requires A2A adenosine receptors.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Progressive degeneration of nigrostriatal dopamine neurons following intrastriatal terminal lesions with 6-hydroxydopamine: a combined retrograde tracing and immunocytochemical study in the rat.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2970925

Differential expression of mGluR5 metabotropic glutamate receptor mRNA by rat striatal neurons

28 October 2018

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12 December 2020

Dose-dependent lesions of the dopaminergic nigrostriatal pathway induced by intrastriatal injection of 6-hydroxydopamine

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12 December 2020

Synthesis and preliminary biological evaluation of 3-[(18)F]fluoro-5-(2-pyridinylethynyl)benzonitrile as a PET radiotracer for imaging metabotropic glutamate receptor subtype 5

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12 December 2020

Subtype selective antagonism of substantia nigra pars compacta Group I metabotropic glutamate receptors protects the nigrostriatal system against 6-hydroxydopamine toxicity in vivo

1 reference

12 December 2020

10.1016/J.NEULET.2010.09.043

Identifiers

DOI

1 reference

1 August 2017

1 reference

1 August 2017

1 reference