(Q34269646)

1 August 2017

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title

Molecular therapeutics of liver disease (English)

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1 August 2017

Davern TJ

1

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1 August 2017

publication date

1 May 2001

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1 August 2017

published in

Clinics in liver disease

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1 August 2017

volume

5

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1 August 2017

issue

2

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1 August 2017

page(s)

381-414, vi

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Immunology: improving on nature in the twenty-first century

1 August 2017

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Gene therapy strategies to facilitate organ transplantation

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Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

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7 January 2021

Treatment of murine lupus with CTLA4Ig

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7 January 2021

Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis

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7 January 2021

Gene transfer by lentiviral vectors is limited by nuclear translocation and rescued by HIV-1 pol sequences

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7 January 2021

Treatment of the Crigler-Najjar syndrome type I with hepatocyte transplantation

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7 January 2021

Mechanisms and therapy of hepatic fibrosis: report of the AASLD Single Topic Basic Research Conference

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7 January 2021

Nucleocytoplasmic transport

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7 January 2021

TRAIL: a molecule with multiple receptors and control mechanisms

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7 January 2021

Principles of therapeutic liver repopulation.

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7 January 2021

A pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia

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7 January 2021

Successful ex vivo gene therapy directed to liver in a patient with familial hypercholesterolaemia

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7 January 2021

Transplantation of anergic histoincompatible bone marrow allografts

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7 January 2021

Mechanisms of cell engraftment during liver repopulation with hepatocyte transplantation

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

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7 January 2021

The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells

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7 January 2021

Molecular genetics of the LDL receptor gene in familial hypercholesterolemia

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7 January 2021

Induction of central tolerance by intrathymic inoculation of adenoviral antigens into the host thymus permits long-term gene therapy in Gunn rats

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7 January 2021

Insertion of the adenoviral E3 region into a recombinant viral vector prevents antiviral humoral and cellular immune responses and permits long-term gene expression

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7 January 2021

Oral tolerization to adenoviral antigens permits long-term gene expression using recombinant adenoviral vectors

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7 January 2021

Adenovirus-mediated gene therapy of liver diseases

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7 January 2021

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

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7 January 2021

In vivo selection using a cell-growth switch

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7 January 2021

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

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7 January 2021

Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors

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7 January 2021

Cellular immune response to adenoviral vector infected cells does not require de novo viral gene expression: implications for gene therapy.

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7 January 2021

Retroviral vectors for liver-directed gene therapy

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7 January 2021

Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand

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7 January 2021

Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administration

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7 January 2021

Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector.

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7 January 2021

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver

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7 January 2021

A "distant" bystander effect of suicide gene therapy: regression of nontransduced tumors together with a distant transduced tumor

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7 January 2021

A stable system for the high-titer production of multiply attenuated lentiviral vectors

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7 January 2021

Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes.

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7 January 2021

Adenoviral vectors for gene transfer

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7 January 2021

Genetic targeting of adenoviral vectors

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7 January 2021

Generation of recombinant adenovirus vectors with modified fibers for altering viral tropism.

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7 January 2021

Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide

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7 January 2021

Gene repair using chimeric RNA/DNA oligonucleotides

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7 January 2021

Correction of the UDP-glucuronosyltransferase gene defect in the gunn rat model of crigler-najjar syndrome type I with a chimeric oligonucleotide

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7 January 2021

Minding the Cs and Gs

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7 January 2021

Advances in gene targeting methods

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7 January 2021

Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine

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7 January 2021

Purified hematopoietic stem cells can differentiate into hepatocytes in vivo.

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7 January 2021

Hepatocyte transplantation

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7 January 2021

The CD40 pathway in allograft rejection, acceptance, and tolerance

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7 January 2021

Human immunodeficiency virus infection of cells arrested in the cell cycle

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7 January 2021

Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virus

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7 January 2021

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

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7 January 2021

Regulation of self-tolerance by CD80/CD86 interactions

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7 January 2021

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.

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7 January 2021

Transient immunosuppression allows transgene expression following readministration of adeno-associated viral vectors

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7 January 2021

Nonrandom transduction of recombinant adeno-associated virus vectors in mouse hepatocytes in vivo: cell cycling does not influence hepatocyte transduction

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7 January 2021

The kinetics of rAAV integration in the liver

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7 January 2021

Selective repopulation of normal mouse liver by Fas/CD95-resistant hepatocytes

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7 January 2021

Gene transfer by retrovirus vectors occurs only in cells that are actively replicating at the time of infection

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7 January 2021

Protein evolution by molecular breeding

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7 January 2021

Rescue, propagation, and partial purification of a helper virus-dependent adenovirus vector

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7 January 2021

Expanded-capacity adenoviral vectors--the helper-dependent vectors

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7 January 2021

Increasing the size of rAAV-mediated expression cassettes in vivo by intermolecular joining of two complementary vectors

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7 January 2021

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

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7 January 2021

Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.

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7 January 2021

Efficient lentiviral transduction of liver requires cell cycling in vivo

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7 January 2021

A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signal

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7 January 2021

Hepatic gene therapy using adeno-associated virus vectors

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7 January 2021

Applications of DNA shuffling to pharmaceuticals and vaccines

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7 January 2021

Inhibition of tumor necrosis factor alpha by an adenovirus-encoded soluble fusion protein extends transgene expression in the liver and lung

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7 January 2021

Bone marrow as a potential source of hepatic oval cells

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7 January 2021

Immune tolerance and gene therapy in transplantation

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Adeno-associated virus 2-mediated gene transfer in vivo: organ-tropism and expression of transduced sequences in mice

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7 January 2021

Adeno-associated virus type 2-mediated gene transfer: correlation of tyrosine phosphorylation of the cellular single-stranded D sequence-binding protein with transgene expression in human cells in vitro and murine tissues in vivo

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7 January 2021

Costimulatory B7 molecules in the pathogenesis of infectious and autoimmune diseases

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7 January 2021

Replacement of diseased mouse liver by hepatic cell transplantation

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

A novel mechanism of retrovirus inactivation in human serum mediated by anti-alpha-galactosyl natural antibody

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7 January 2021

Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery

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7 January 2021

Gene therapy of viral hepatitis and hepatocellular carcinoma.

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7 January 2021

Human gene targeting by viral vectors

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7 January 2021

Inducible gene expression in mammalian cells and transgenic mice

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7 January 2021

Targeted integration of adeno-associated virus (AAV) into human chromosome 19

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

The role of T-cell costimulatory activation pathways in transplant rejection

1 reference

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity.

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Molecular breeding of viruses

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Hepatocyte transplantation for the treatment of human disease

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Overcoming adeno-associated virus vector size limitation through viral DNA heterodimerization

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Long term correction of bilirubin-UDP-glucuronosyltransferase deficiency in Gunn rats by administration of a recombinant adenovirus during the neonatal period

1 reference

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Expression and antitumor effects of TRAIL in human cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

US gene therapy in crisis

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Derivation of hepatocytes from bone marrow cells in mice after radiation-induced myeloablation

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Cytokines in alcoholic and nonalcoholic steatohepatitis

1 reference

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Inhibition of TNF-induced apoptosis by NF-kappa B.

1 reference

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Immune responses to adenoviruses: viral evasion mechanisms and their implications for the clinic.

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Gene therapy and allotransplantation

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Chemotherapeutic agents augment TRAIL-induced apoptosis in human hepatocellular carcinoma cell lines

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Targeted gene correction: a new strategy for molecular medicine

1 reference

https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Reduced inflammatory response to plasmid DNA vectors by elimination and inhibition of immunostimulatory CpG motifs

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

Biomedical discovery with DNA arrays

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

The physician-scientist: career issues and challenges at the year 2000

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

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https://api.crossref.org/works/10.1016%2FS1089-3261%2805%2970171-9

7 January 2021

From expressed sequence tags to 'epigenomics': an understanding of disease processes

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7 January 2021

10.1016/S1089-3261(05)70171-9

Identifiers

DOI

1 reference

1 August 2017

1 reference