(Q34272586)

1 August 2017

Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea (English)

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1 August 2017

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S Seino

1

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1 August 2017

4 May 2012

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1 August 2017

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1 August 2017

55

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1 August 2017

8

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1 August 2017

2096-2108

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https://scigraph.springernature.com/pub.10.1007/s00125-012-2562-9

1 August 2017

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cites work

Quantitative aspects of the reaction between insulin and insulin-binding antibody

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https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The role of cyclic AMP in insulin release

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

An in Vitro system for studying insulin release caused by secretory granules-plasma membrane interaction: definition of the system

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Regulation of insulin secretion studied with pieces of rabbit pancreas incubated in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

ATP-regulated K+ channels in cardiac muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Glucose dependent K+-channels in pancreatic beta-cells are regulated by intracellular ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Electrophysiology of the pancreatic beta-cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Regulation of insulin secretion: a matter of phase control and amplitude modulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Two sites of glucose control of insulin release with distinct dependence on the energy state in pancreatic B-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Post-priming actions of ATP on Ca2+-dependent exocytosis in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Fatty acid signaling in the beta-cell and insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Dynamics of Insulin Secretion by the Perfused Rat Pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Insulin granule dynamics in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Synaptic vesicle exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Novel aspects of the molecular mechanisms controlling insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Stimulation of insulin release by glucose is associated with an increase in the number of docked granules in the beta-cells of rat pancreatic islets

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Simultaneous evanescent wave imaging of insulin vesicle membrane and cargo during a single exocytotic event

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Imaging exocytosis of single insulin secretory granules with evanescent wave microscopy: distinct behavior of granule motion in biphasic insulin release

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Docking is not a prerequisite but a temporal constraint for fusion of secretory granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Cell-substrate contacts illuminated by total internal reflection fluorescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

SNARE conformational changes that prepare vesicles for exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Dynamics of insulin secretion and the clinical implications for obesity and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Roles of cAMP signalling in insulin granule exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Distinct Rab binding specificity of Rim1, Rim2, rabphilin, and Noc2. Identification of a critical determinant of Rab3A/Rab27A recognition by Rim2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

ELKS, a protein structurally related to the active zone-associated protein CAST, is expressed in pancreatic beta cells and functions in insulin exocytosis: interaction of ELKS with exocytotic machinery analyzed by total internal reflection fluoresce

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Impaired insulin secretion and glucose intolerance in synaptotagmin-7 null mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Synaptotagmin V and IX isoforms control Ca2+ -dependent insulin exocytosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Rim2alpha determines docking and priming states in insulin granule exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The exocyst complex in polarized exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Distinct effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 on insulin secretion and gut motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Niflumic acid-sensitive ion channels play an important role in the induction of glucose-stimulated insulin secretion by cyclic AMP in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The sulphonylurea receptor may be an ATP-sensitive potassium channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Reconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Molecular biology of adenosine triphosphate-sensitive potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Physiological and pathophysiological roles of ATP-sensitive K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Sulphonylurea action revisited: the post-cloning era.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Testing the bipartite model of the sulfonylurea receptor binding site: binding of A-, B-, and A + B-site ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Modeling K(ATP) channel gating and its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Abnormalities of pancreatic islets by targeted expression of a dominant-negative KATP channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Sur1 knockout mice. A model for K(ATP) channel-independent regulation of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Glucose controls cytosolic Ca2+ and insulin secretion in mouse islets lacking adenosine triphosphate-sensitive K+ channels owing to a knockout of the pore-forming subunit Kir6.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Activating mutations in the gene encoding the ATP-sensitive potassium-channel subunit Kir6.2 and permanent neonatal diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Hyperinsulinism and diabetes: genetic dissection of beta cell metabolism-excitation coupling in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

New uses for old drugs: neonatal diabetes and sulphonylureas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

A K ATP channel-dependent pathway within alpha cells regulates glucagon release from both rodent and human islets of Langerhans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Coordinate regulation of glucose transporter function, number, and gene expression by insulin and sulfonylureas in L6 rat skeletal muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

ATP-sensitive K+ channel-mediated glucose uptake is independent of IRS-1/phosphatidylinositol 3-kinase signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Disruption of Sur2-containing K(ATP) channels enhances insulin-stimulated glucose uptake in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Roles of ATP-sensitive K+ channels as metabolic sensors: studies of Kir6.x null mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The biology of incretin hormones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The Physiology of Glucagon-like Peptide 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Unraveling the science of incretin biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Role of VIP and PACAP in islet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Type VIII adenylyl cyclase in rat beta cells: coincidence signal detector/generator for glucose and GLP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

A family of cAMP-binding proteins that directly activate Rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Epac: defining a new mechanism for cAMP action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Characterization of the gene EPAC2: structure, chromosomal localization, tissue expression, and identification of the liver-specific isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Direct spatial control of Epac1 by cyclic AMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Functional localization of cAMP signalling in cardiac myocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

SUR1 regulates PKA-independent cAMP-induced granule priming in mouse pancreatic B-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Monitoring protein conformations and interactions by fluorescence resonance energy transfer between mutants of green fluorescent protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Sulfonylurea action re-revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Insulin biosynthesis and secretion--a still unsettled topic

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Intracellular ATP directly blocks K+ channels in pancreatic B-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00125-012-2562-9

Rapid ATP-Dependent Priming of Secretory Granules Precedes Ca2+-Induced Exocytosis in Mouse Pancreatic B-Cells

21 January 2018

1 reference

12 December 2020

cAMP-dependent phosphorylation of the cardiac-type alpha 1 subunit of the voltage-dependent Ca2+ channel in a murine pancreatic beta-cell line

1 reference

12 December 2020

ELKS, a protein structurally related to the active zone protein CAST, is involved in Ca2+-dependent exocytosis from PC12 cells

1 reference

12 December 2020

Protein kinase A-dependent phosphorylation of GLUT2 in pancreatic beta cells

1 reference

12 December 2020

PKC-Dependent Stimulation of Exocytosis by Sulfonylureas in Pancreatic beta Cells

1 reference

12 December 2020

ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis.

1 reference

12 December 2020

L-type calcium channels in insulin-secreting cells: biochemical characterization and phosphorylation in RINm5F cells.

1 reference

12 December 2020

Banting lecture 1990. Beta-cells in type II diabetes mellitus

1 reference

12 December 2020

Glucagonlike peptide I (7-37) actions on endocrine pancreas

1 reference

12 December 2020

EFFECTS OF CARBOHYDRATES ON SECRETION OF INSULIN FROM ISOLATED RAT PANCREAS

1 reference

12 December 2020

Regulation of insulin release by calcium

1 reference

12 December 2020

Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion

1 reference

12 December 2020

Sulphonylurea stimulates glucose uptake in rats through an ATP-sensitive K+ channel dependent mechanism

1 reference

12 December 2020

Intracellular localization and molecular heterogeneity of the sulphonylurea receptor in insulin-secreting cells

1 reference

12 December 2020

Mechanism of glucose-induced insulin secretion

1 reference

12 December 2020

Adenylyl cyclase isoform expression in non-diabetic and diabetic Goto-Kakizaki (GK) rat pancreas. Evidence for distinct overexpression of type-8 adenylyl cyclase in diabetic GK rat islets

1 reference

12 December 2020

10.1007/S00125-012-2562-9

Identifiers

DOI

1 reference

PubMed ID

22555472

Dimensions Publication ID

1 August 2017

0 references

1 reference

PubMed ID

22555472