(Q34273832)

1 August 2017

title

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells (English)

1 reference

1 August 2017

Brian Budke

1

1 reference

1 August 2017

Hillary L Logan

2

1 reference

1 August 2017

Jay H Kalin

3

1 reference

1 August 2017

Anna S Zelivianskaia

4

1 reference

1 August 2017

William Cameron McGuire

5

1 reference

1 August 2017

Luke L Miller

6

1 reference

1 August 2017

Jeremy M Stark

7

1 reference

1 August 2017

Alan P Kozikowski

8

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1 August 2017

Douglas K Bishop

9

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1 August 2017

Philip P Connell

10

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1 August 2017

language of work or name

English

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publication date

9 May 2012

1 reference

1 August 2017

published in

Nucleic Acids Research

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1 August 2017

volume

40

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1 August 2017

issue

15

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1 August 2017

page(s)

7347-7357

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Creative Commons Attribution-NonCommercial 3.0 Unported

1 August 2017

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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6 July 2018

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6 July 2018

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A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex

6 July 2018

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RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors

6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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Crystal structure of a Rad51 filament

6 July 2018

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A hot spot for RAD51C interactions revealed by a peptide that sensitizes cells to cisplatin

6 July 2018

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6 July 2018

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Role of RAD52 epistasis group genes in homologous recombination and double-strand break repair

6 July 2018

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Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

6 July 2018

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Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange

6 July 2018

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6 July 2018

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Homologous recombinational repair of DNA ensures mammalian chromosome stability

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs

6 July 2018

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Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells

6 July 2018

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Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

6 July 2018

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Molecular dissection of interactions between Rad51 and members of the recombination-repair group

6 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Over-expression of wild-type Rad51 correlates with histological grading of invasive ductal breast cancer

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Expression of BRC repeats in breast cancer cells disrupts the BRCA2-Rad51 complex and leads to radiation hypersensitivity and loss of G(2)/M checkpoint control

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

XRCC3 promotes homology-directed repair of DNA damage in mammalian cells

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Overexpression of Rad51 protein stimulates homologous recombination and increases resistance of mammalian cells to ionizing radiation

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

In vitro and in vivo potentiation of radiosensitivity of malignant gliomas by antisense inhibition of the RAD51 gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

RecA homologs Dmc1 and Rad51 interact to form multiple nuclear complexes prior to meiotic chromosome synapsis.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Cooperative and noncooperative binding of protein ligands to nucleic acid lattices: experimental approaches to the determination of thermodynamic parameters.

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3424541

Homologous recombinational repair vis-à-vis chlorambucil resistance in chronic lymphocytic leukemia

6 July 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

The role of RAD51 in etoposide (VP16) resistance in small cell lung cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Mutation of the RAD51C gene in a Fanconi anemia-like disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Tunable reagents for multi-functional bioconjugation: reversible or permanent chemical modification of proteins and peptides by control of maleimide hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Crystal structure of archaeal recombinase RADA: a snapshot of its extended conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Crystal structure of an ATPase-active form of Rad51 homolog from Methanococcus voltae. Insights into potassium dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Location of tyrosine 315, a target for phosphorylation by cAbl tyrosine kinase, at the edge of the subunit-subunit interface of the human Rad51 filament

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKS353

Combined evaluation of Rad51 and ERCC1 expressions for sensitivity to platinum agents in non-small cell lung cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22573178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKS353

1 reference

1 August 2017

1 reference

1 August 2017

1 reference