(Q34278668)

1 August 2017

title

Intronic RNAs mediate EZH2 regulation of epigenetic targets (English)

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8

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Antonio Gómez

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Anna Portela

object named as

Anna Portela

3

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author name string

Sònia Guil

1

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Marta Soler

2

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Jordi Carrère

4

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Elena Fonalleras

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Alberto Villanueva

7

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1 August 2017

publication date

3 June 2012

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Nature Structural & Molecular Biology

1 August 2017

published in

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volume

19

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issue

7

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1 August 2017

page(s)

664-670

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Polycomb silencers control cell fate, development and cancer

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cites work

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Structure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1b

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A phosphorylated form of Mel-18 targets the Ring1B histone H2A ubiquitin ligase to chromatin

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Genome regulation by polycomb and trithorax proteins

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Polycomb group proteins: navigators of lineage pathways led astray in cancer

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Roles of the EZH2 histone methyltransferase in cancer epigenetics

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Integrative genomics analysis reveals silencing of beta-adrenergic signaling by polycomb in prostate cancer

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Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer.

21 January 2018

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Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells

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Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells

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Jarid2 and PRC2, partners in regulating gene expression

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JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells

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Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.

21 January 2018

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Role for the MOV10 RNA helicase in polycomb-mediated repression of the INK4a tumor suppressor.

21 January 2018

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Role of histone H3 lysine 27 methylation in X inactivation

21 January 2018

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Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs

21 January 2018

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Polycomb proteins targeted by a short repeat RNA to the mouse X chromosome

21 January 2018

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Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

21 January 2018

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Short RNAs are transcribed from repressed polycomb target genes and interact with polycomb repressive complex-2.

21 January 2018

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Long noncoding RNA as modular scaffold of histone modification complexes

21 January 2018

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Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses

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Molecular mechanisms of long noncoding RNAs

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Long non-coding RNAs: insights into functions

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Non-coding RNAs in human disease

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Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis

21 January 2018

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Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers.

21 January 2018

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Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

21 January 2018

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Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA

21 January 2018

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Molecular interplay of the noncoding RNA ANRIL and methylated histone H3 lysine 27 by polycomb CBX7 in transcriptional silencing of INK4a

21 January 2018

1 reference

Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

21 January 2018

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Regulation of X-chromosome inactivation by the X-inactivation centre.

21 January 2018

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Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

21 January 2018

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CLIP: a method for identifying protein-RNA interaction sites in living cells

21 January 2018

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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution

21 January 2018

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Long non-coding RNA ANRIL is required for the PRC2 recruitment to and silencing of p15(INK4B) tumor suppressor gene

21 January 2018

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Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27.

21 January 2018

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Genome-wide identification of polycomb-associated RNAs by RIP-seq

21 January 2018

1 reference

Conserved non-genic sequences - an unexpected feature of mammalian genomes

21 January 2018

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Critical association of ncRNA with introns

21 January 2018

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Conserved tissue expression signatures of intronic noncoding RNAs transcribed from human and mouse loci

21 January 2018

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Genome mapping and expression analyses of human intronic noncoding RNAs reveal tissue-specific patterns and enrichment in genes related to regulation of transcription

21 January 2018

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Micro-RNA-like effects of complete intronic sequences

21 January 2018

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Vernalization-mediated epigenetic silencing by a long intronic noncoding RNA.

21 January 2018

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Epigenetics in alternative pre-mRNA splicing

21 January 2018

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CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

21 January 2018

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

21 January 2018

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Polycomb complexes repress developmental regulators in murine embryonic stem cells

21 January 2018

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Control of developmental regulators by Polycomb in human embryonic stem cells

21 January 2018

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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

21 January 2018

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Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors.

21 January 2018

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SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells

21 January 2018

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Enhanced SMYD3 expression is essential for the growth of breast cancer cells

21 January 2018

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Aberrations of EZH2 in cancer

21 January 2018

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A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

21 January 2018

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Noncoding RNA gas5 is a growth arrest- and starvation-associated repressor of the glucocorticoid receptor

21 January 2018

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Induced ncRNAs allosterically modify RNA-binding proteins in cis to inhibit transcription

21 January 2018

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hnRNP A/B proteins are required for inhibition of HIV-1 pre-mRNA splicing

21 January 2018

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Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NSMB.2315

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1 August 2017

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