(Q34282044)

1 August 2017

title

Overexpression of MEKK3 confers resistance to apoptosis through activation of NFkappaB. (English)

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1 August 2017

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Ajoy K Samanta

1

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1 August 2017

Helen J Huang

series ordinal

2

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1 August 2017

Robert C Bast

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3

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1 August 2017

Warren S-L Liao

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4

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1 August 2017

language of work or name

English

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publication date

8 December 2003

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Journal of Biological Chemistry

1 August 2017

published in

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1 August 2017

volume

279

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1 August 2017

issue

9

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1 August 2017

page(s)

7576-7583

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Mammalian MAP kinase signalling cascades

1 August 2017

cites work

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https://api.crossref.org/works/10.1074%2FJBC.M311659200

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Role of MAP kinase in tumor progression and invasion

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Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

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NAK is an IkappaB kinase-activating kinase

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Mekk3 is essential for early embryonic cardiovascular development

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The essential role of MEKK3 in TNF-induced NF-kappaB activation

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NF-kappaB in cancer: a marked target

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NF-kappaB at the crossroads of life and death

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The IKK/NF-kappa B pathway

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Activators and target genes of Rel/NF-kappaB transcription factors

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Inhibition of NF-kappaB activity decreases the VEGF mRNA expression in MDA-MB-231 breast cancer cells

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Apoptosis and nuclear factor-kappa B: a tale of association and dissociation

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NF-kappaB in cancer: from innocent bystander to major culprit

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Mechanisms of NF-kappaB activation by the HTLV type 1 tax protein

21 January 2018

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Persistent activation of NF-kappa B by the tax transforming protein involves chronic phosphorylation of IkappaB kinase subunits IKKbeta and IKKgamma

21 January 2018

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Oncoprotein suppression of tumor necrosis factor-induced NF kappa B activation is independent of Raf-controlled pathways

21 January 2018

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Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptors

21 January 2018

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21 January 2018

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Up-regulation of vascular endothelial growth factor C in breast cancer cells by heregulin-beta 1. A critical role of p38/nuclear factor-kappa B signaling pathway

21 January 2018

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Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells

21 January 2018

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GRP94/gp96 elicits ERK activation in murine macrophages. A role for endotoxin contamination in NF-kappa B activation and nitric oxide production

21 January 2018

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Interleukin-4 down-regulates both forms of tumor necrosis factor receptor and receptor-mediated apoptosis, NF-kappaB, AP-1, and c-Jun N-terminal kinase. Comparison with interleukin-13.

21 January 2018

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PARP is important for genomic stability but dispensable in apoptosis

21 January 2018

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Role of poly(ADP-ribose) polymerase (PARP) cleavage in apoptosis. Caspase 3-resistant PARP mutant increases rates of apoptosis in transfected cells.

21 January 2018

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BCL-2 in prostate cancer: a minireview

21 January 2018

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Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

21 January 2018

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Akt stimulates the transactivation potential of the RelA/p65 Subunit of NF-kappa B through utilization of the Ikappa B kinase and activation of the mitogen-activated protein kinase p38.

21 January 2018

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Akt is a major downstream target of PI3-kinase involved in angiotensin II-induced proliferation

21 January 2018

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Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

21 January 2018

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Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling

21 January 2018

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Map kinase signaling pathways and hematologic malignancies

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311659200

Combined action of ERK and NF kappa B mediates the protective effect of phorbol ester on Fas-induced apoptosis in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M311659200

Synthetic inhibitor of matrix metalloproteases decreases tumor growth and metastases in a syngeneic model of rat prostate cancer in vivo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311659200

NIK is a component of the EGF/heregulin receptor signaling complexes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M311659200

Chemotherapeutic drugs--more really is not better

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M311659200

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1 August 2017

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