(Q34282191)

1 August 2017

title

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors (English)

1 reference

1 August 2017

1 reference

Lynda Coughlan

3

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Alan L Parker

Alan L Parker

9

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Stuart A Nicklin

Stuart A Nicklin

15

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John H. McVey

John H McVey

14

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Simon N. Waddington

Simon N Waddington

6

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Nico van Rooijen

13

Nico van Rooijen

1 reference

1 August 2017

Raul Alba

1

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1 August 2017

Angela C Bradshaw

2

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1 August 2017

Laura Denby

4

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1 August 2017

Robert A McDonald

5

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1 August 2017

Suzanne M K Buckley

7

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1 August 2017

Jenny A Greig

8

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1 August 2017

Ashley M Miller

10

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1 August 2017

Hongjie Wang

11

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1 August 2017

Andre Lieber

12

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1 August 2017

Andrew H Baker

16

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1 August 2017

language of work or name

English

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publication date

7 July 2010

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1 August 2017

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1 August 2017

volume

116

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1 August 2017

issue

15

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1 August 2017

page(s)

2656-2664

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describes a project that uses

1 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2974579/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Influence of coagulation factor x on in vitro and in vivo gene delivery by adenovirus (Ad) 5, Ad35, and chimeric Ad5/Ad35 vectors

6 July 2018

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Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

6 July 2018

1 reference

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Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.

6 July 2018

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The Cell Adhesion Molecule “CAR” and Sialic Acid on Human Erythrocytes Influence Adenovirus In Vivo Biodistribution

6 July 2018

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Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement

6 July 2018

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In vitro and in vivo properties of adenovirus vectors with increased affinity to CD46

6 July 2018

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Substitution of hexon hypervariable region 5 of adenovirus serotype 5 abrogates blood factor binding and limits gene transfer to liver

6 July 2018

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Comparative seroprevalence and immunogenicity of six rare serotype recombinant adenovirus vaccine vectors from subgroups B and D

6 July 2018

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Cancer selective adenoviruses

6 July 2018

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Minimal hepatic toxicity of Onyx-015: spatial restriction of coxsackie-adenoviral receptor in normal liver

6 July 2018

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Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

6 July 2018

1 reference

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A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.

6 July 2018

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Neutrophils interact with adenovirus vectors via Fc receptors and complement receptor 1.

6 July 2018

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Structure and function of the spleen

6 July 2018

1 reference

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Adenovirus Binding to Blood Factors Results in Liver Cell Infection and Hepatotoxicity

6 July 2018

1 reference

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Effect of adenovirus serotype 5 fiber and penton modifications on in vivo tropism in rats

6 July 2018

1 reference

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CAR- or alphav integrin-binding ablated adenovirus vectors, but not fiber-modified vectors containing RGD peptide, do not change the systemic gene transfer properties in mice

6 July 2018

1 reference

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A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency

6 July 2018

1 reference

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Construction of a pseudoreceptor that mediates transduction by adenoviruses expressing a ligand in fiber or penton base.

6 July 2018

1 reference

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The coxsackievirus-adenovirus receptor protein can function as a cellular attachment protein for adenovirus serotypes from subgroups A, C, D, E, and F

6 July 2018

1 reference

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Complementation of a fibre mutant adenovirus by packaging cell lines stably expressing the adenovirus type 5 fibre protein

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Enhancement of in vivo adenovirus-mediated gene transfer and expression by prior depletion of tissue macrophages in the target organ

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Integrins alpha v beta 3 and alpha v beta 5 promote adenovirus internalization but not virus attachment

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Adenovirus-mediated in vivo gene transfer and expression in normal rat liver

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

International epidemiology of human pre-existing adenovirus (Ad) type-5, type-6, type-26 and type-36 neutralizing antibodies: Correlates of high Ad5 titers and implications for potential HIV vaccine trials

6 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Virus binding to a plasma membrane receptor triggers interleukin-1 alpha-mediated proinflammatory macrophage response in vivo

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Adenovirus serotype 5 hexon mediates liver gene transfer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Targeting of adenovirus serotype 5 (Ad5) and 5/47 pseudotyped vectors in vivo: fundamental involvement of coagulation factors and redundancy of CAR binding by Ad5.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Fiber-modified adenovirus vectors decrease liver toxicity through reduced IL-6 production

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Modified adenoviral vectors ablated for coxsackievirus-adenovirus receptor, alphav integrin, and heparan sulfate binding reduce in vivo tissue transduction and toxicity.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Neutralizing antibodies to adenovirus serotype 5 vaccine vectors are directed primarily against the adenovirus hexon protein

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Recombinant adenovirus vectors activate the alternative complement pathway, leading to the binding of human complement protein C3 independent of anti-ad antibodies

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Receptor interactions involved in adenoviral-mediated gene delivery after systemic administration in non-human primates

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Phase II Trial of Intravenous CI-1042 in Patients With Metastatic Colorectal Cancer

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophages

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Sequestration of adenoviral vector by Kupffer cells leads to a nonlinear dose response of transduction in liver

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974579

Macrophage subset repopulation in the spleen: differential kinetics after liposome-mediated elimination

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20610817

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1182/BLOOD-2009-12-260026

1 reference

1 August 2017

1 reference

1 August 2017

1 reference