(Q40479387)

English

A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer.

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Europe PubMed Central

PubMed publication ID

20 September 2017

A phase I trial of intravenous CG7870, a replication-selective, prostate-specific antigen-targeted oncolytic adenovirus, for the treatment of hormone-refractory, metastatic prostate cancer. (English)

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Europe PubMed Central

PubMed publication ID

20 September 2017

phase I clinical trial

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oncolytic virus

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based on heuristic

inferred from title

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based on heuristic

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12

object named as

George Wilding

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Europe PubMed Central

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20 September 2017

1

object named as

Eric J Small

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20 September 2017

Michael A. Carducci

2

object named as

Michael A Carducci

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20 September 2017

author name string

James M Burke

3

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20 September 2017

Ron Rodriguez

4

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20 September 2017

Lawrence Fong

5

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

Lynn van Ummersen

6

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20 September 2017

D C Yu

7

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20 September 2017

Junko Aimi

8

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20 September 2017

Dale Ando

9

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20 September 2017

Peter Working

10

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20 September 2017

David Kirn

11

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20 September 2017

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publication date

9 May 2006

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20 September 2017

Molecular Therapy

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20 September 2017

14

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20 September 2017

1

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20 September 2017

107-117

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20 September 2017

Replication-selective virotherapy for cancer: Biological principles, risk management and future directions

1 reference

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7 January 2021

Replication-selective oncolytic adenoviruses: virotherapy aimed at genetic targets in cancer

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ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

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Clinical research results with dl1520 (Onyx-015), a replication-selective adenovirus for the treatment of cancer: what have we learned?

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a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

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Intra-arterial administration of a replication-selective adenovirus (dl1520) in patients with colorectal carcinoma metastatic to the liver: a phase I trial

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Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity

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Phase II Trial of Intravenous CI-1042 in Patients With Metastatic Colorectal Cancer

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Intravascular adenoviral agents in cancer patients: lessons from clinical trials

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Chemotherapy with mitoxantrone plus prednisone or prednisone alone for symptomatic hormone-resistant prostate cancer: a Canadian randomized trial with palliative end points.

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A novel three-pronged approach to kill cancer cells selectively: concomitant viral, double suicide gene, and radiotherapy

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Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer

1 reference

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TNFerade biologic, an adenovector with a radiation-inducible promoter, carrying the human tumor necrosis factor alpha gene: a phase I study in patients with solid tumors

1 reference

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Prostate cancer update

1 reference

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Molecular-genetic imaging: current and future perspectives

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Cytokines in adenoviral disease in children: association of interleukin-6, interleukin-8, and tumor necrosis factor alpha levels with clinical outcome

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Tumour necrosis factor in man: clinical and biological observations

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Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

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A pilot study of in vivo liver-directed gene transfer with an adenoviral vector in partial ornithine transcarbamylase deficiency

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Replication-selective adenoviruses as oncolytic agents

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HCAR and MCAR: the human and mouse cellular receptors for subgroup C adenoviruses and group B coxsackieviruses

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Ablating CAR and integrin binding in adenovirus vectors reduces nontarget organ transduction and permits sustained bloodstream persistence following intraperitoneal administration

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Polymer-coated adenovirus permits efficient retargeting and evades neutralising antibodies.

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Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer

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Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancer

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An adenovirus E1A mutant that demonstrates potent and selective systemic anti-tumoral efficacy

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7 January 2021

Pre-existent adenovirus antibody inhibits systemic toxicity and antitumor activity of CN706 in the nude mouse LNCaP xenograft model: implications and proposals for human therapy

1 reference

https://api.crossref.org/works/10.1016%2FJ.YMTHE.2006.02.011

7 January 2021

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10.1016/J.YMTHE.2006.02.011

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 September 2017

ResearchGate publication ID

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